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Protein

60S acidic ribosomal protein P1

Gene

Rplp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays an important role in the elongation step of protein synthesis.

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: GO_Central
  • positive regulation of protein kinase activity Source: GO_Central
  • regulation of translation Source: MGI
  • translational elongation Source: InterPro

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P1
Gene namesi
Name:Rplp1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1927099 Rplp1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001576872 – 11460S acidic ribosomal protein P1Add BLAST113

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei101PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiP47955
PaxDbiP47955
PeptideAtlasiP47955
PRIDEiP47955
TopDownProteomicsiP47955

PTM databases

iPTMnetiP47955
PhosphoSitePlusiP47955
SwissPalmiP47955

Expressioni

Gene expression databases

BgeeiENSMUSG00000007892
CleanExiMM_RPLP1
ExpressionAtlasiP47955 baseline and differential
GenevisibleiP47955 MM

Interactioni

Subunit structurei

Heterodimer with RPLP2 at the lateral ribosomal stalk of the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi207787, 7 interactors
IntActiP47955, 7 interactors
MINTiP47955
STRINGi10090.ENSMUSP00000008036

Structurei

3D structure databases

ProteinModelPortaliP47955
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1762 Eukaryota
COG2058 LUCA
GeneTreeiENSGT00550000074698
HOGENOMiHOG000229898
HOVERGENiHBG002291
InParanoidiP47955
KOiK02942
OMAiQELLCTY
OrthoDBiEOG091G17EU
PhylomeDBiP47955
TreeFamiTF312932

Family and domain databases

Gene3Di1.10.10.1410, 1 hit
HAMAPiMF_01478 Ribosomal_L12_arch, 1 hit
InterProiView protein in InterPro
IPR038716 P1/P2_N_sf
IPR027534 Ribosomal_L12

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47955-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVSVE PFWPGLFAKA
60 70 80 90 100
LANVNIGSLI CNVGAGGPAP AAGAAPAGGA APSTAAAPAE EKKVEAKKEE
110
SEESEDDMGF GLFD
Length:114
Mass (Da):11,475
Last modified:February 1, 1996 - v1
Checksum:i63C344A2772350D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29402 mRNA Translation: AAA70106.1
AK007832 mRNA Translation: BAB25292.1
AK010656 mRNA Translation: BAB27095.1
AK088070 mRNA Translation: BAC40128.1
BC058685 mRNA Translation: AAH58685.1
CCDSiCCDS23260.1
RefSeqiNP_061341.1, NM_018853.3
UniGeneiMm.3158

Genome annotation databases

EnsembliENSMUST00000008036; ENSMUSP00000008036; ENSMUSG00000007892
GeneIDi56040
KEGGimmu:56040
UCSCiuc009pzt.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRLA1_MOUSE
AccessioniPrimary (citable) accession number: P47955
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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