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UniProtKB - P47929 (LEG7_HUMAN)

Entry version 199 (23 Feb 2022)
Sequence version 2 (23 Jan 2007)
Previous versions | rss
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Protein

Galectin-7

Gene

LGALS7

more
Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis
LigandLectin

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P47929

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P47929

Protein family/group databases

UniLectin database of carbohydrate-binding proteins

More...UniLectini		P47929

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Galectin-7
Short name:
Gal-7
Alternative name(s):
HKL-14
PI7
p53-induced gene 1 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LGALS7
Synonyms:PIG1
AND
Name:LGALS7B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:6568, LGALS7
HGNC:34447, LGALS7B

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		600615, gene
617139, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P47929

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000178934
HostDB:ENSG00000205076

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		3963
653499

Open Targets

More...OpenTargetsi		ENSG00000178934
ENSG00000205076

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162393892

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P47929, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL5008

Drug and drug target database

More...DrugBanki		DB02678, beta-D-Galactosamine
DB02379, Beta-D-Glucose

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LGALS7B

Domain mapping of disease mutations (DMDM)

More...DMDMi		1346431

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000769401 – 136Galectin-7Add BLAST136

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P47929

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P47929

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P47929

MaxQB - The MaxQuant DataBase

More...MaxQBi		P47929

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P47929

PeptideAtlas

More...PeptideAtlasi		P47929

PRoteomics IDEntifications database

More...PRIDEi		P47929

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		55824

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		P47929, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P47929

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P47929

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P47929

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mainly expressed in stratified squamous epithelium.

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By p53/TP53.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000178934, Expressed in skin of abdomen and 86 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P47929, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P47929, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000178934, Tissue enriched (skin)
ENSG00000205076, Tissue enhanced (esophagus, skin)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		110154, 120 interactors
575831, 89 interactors

Protein interaction database and analysis system

More...IntActi		P47929, 63 interactors

Molecular INTeraction database

More...MINTi		P47929

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000313571

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P47929

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P47929, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1136
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Biological Magnetic Resonance Data Bank

More...BMRBi		P47929

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P47929

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P47929

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 136GalectinPROSITE-ProRule annotationAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni70 – 76Beta-galactoside bindingSequence analysis7

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3587, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01040000240531

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_037794_3_3_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P47929

Identification of Orthologs from Complete Genome Data

More...OMAi		LPMGNVR

Database of Orthologous Groups

More...OrthoDBi		1486238at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P47929

TreeFam database of animal gene trees

More...TreeFami		TF315551

Family and domain databases

Conserved Domains Database

More...CDDi		cd00070, GLECT, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR044156, Galectin-like
IPR030640, Galectin_7
IPR001079, Galectin_CRD

The PANTHER Classification System

More...PANTHERi		PTHR11346, PTHR11346, 1 hit
PTHR11346:SF107, PTHR11346:SF107, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00337, Gal-bind_lectin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00908, Gal-bind_lectin, 1 hit
SM00276, GLECT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51304, GALECTIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P47929-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH 
        60         70         80         90        100
FNPRLDTSEV VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA 
       110        120        130 
VVGDAQYHHF RHRLPLARVR LVEVGGDVQL DSVRIF
Length:136
Mass (Da):15,075
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF613D3540331C13F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R281M0R281_HUMAN
Galectin-7
LGALS7
35Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L07769 mRNA Translation: AAA67899.1
U06643 mRNA Translation: AAA86820.1
CR456917 mRNA Translation: CAG33198.1
CH471126 Genomic DNA Translation: EAW56817.1
CH471126 Genomic DNA Translation: EAW56818.1
BC042911 mRNA Translation: AAH42911.2
BC061588 mRNA Translation: AAH61588.1
BC073743 mRNA Translation: AAH73743.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS42565.1

Protein sequence database of the Protein Information Resource

More...PIRi		I55469

NCBI Reference Sequences

More...RefSeqi		NP_001035972.1, NM_001042507.3
NP_002298.1, NM_002307.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000314980; ENSP00000313571; ENSG00000178934
ENST00000378626; ENSP00000367891; ENSG00000205076
ENST00000634448; ENSP00000489395; ENSG00000282902
ENST00000634800; ENSP00000489582; ENSG00000283082

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3963
653499

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:3963
hsa:653499

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000314980.5; ENSP00000313571.3; NM_001042507.4; NP_001035972.1
ENST00000378626.5; ENSP00000367891.3; NM_002307.4; NP_002298.1

UCSC genome browser

More...UCSCi		uc002oje.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Functional Glycomics Gateway - Glycan Binding

Galectin-7

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L07769 mRNA Translation: AAA67899.1
U06643 mRNA Translation: AAA86820.1
CR456917 mRNA Translation: CAG33198.1
CH471126 Genomic DNA Translation: EAW56817.1
CH471126 Genomic DNA Translation: EAW56818.1
BC042911 mRNA Translation: AAH42911.2
BC061588 mRNA Translation: AAH61588.1
BC073743 mRNA Translation: AAH73743.1
CCDSiCCDS42565.1
PIRiI55469
RefSeqiNP_001035972.1, NM_001042507.3
NP_002298.1, NM_002307.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BKZX-ray1.90A/B2-136[»]
2GALX-ray2.00A/B2-136[»]
3GALX-ray1.90A/B2-136[»]
3ZXEX-ray1.67A/B4-136[»]
3ZXFX-ray1.38A/B1-136[»]
4GALX-ray1.95A/B2-136[»]
4UW3X-ray1.48A/B1-136[»]
4UW4X-ray1.77A/B1-136[»]
4UW5X-ray2.04A/B/C/D/E/F1-136[»]
4UW6X-ray1.79A/B1-136[»]
4XBQX-ray2.23A/B1-136[»]
4Y26X-ray2.61A/B4-136[»]
5GALX-ray2.00A/B2-136[»]
5H9QX-ray1.93A/B1-136[»]
5H9SX-ray1.82A/B1-136[»]
6VTOX-ray1.69A/B2-136[»]
6VTPX-ray2.30A/B2-136[»]
6VTQX-ray1.95A/B2-136[»]
6VTRX-ray2.30A/B2-136[»]
6VTSX-ray1.90A/B2-136[»]
BMRBiP47929
SMRiP47929
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi110154, 120 interactors
575831, 89 interactors
IntActiP47929, 63 interactors
MINTiP47929
STRINGi9606.ENSP00000313571

Chemistry databases

BindingDBiP47929
ChEMBLiCHEMBL5008
DrugBankiDB02678, beta-D-Galactosamine
DB02379, Beta-D-Glucose

Protein family/group databases

UniLectiniP47929

PTM databases

GlyGeniP47929, 1 site, 1 O-linked glycan (1 site)
iPTMnetiP47929
PhosphoSitePlusiP47929
SwissPalmiP47929

Genetic variation databases

BioMutaiLGALS7B
DMDMi1346431

Proteomic databases

EPDiP47929
jPOSTiP47929
MassIVEiP47929
MaxQBiP47929
PaxDbiP47929
PeptideAtlasiP47929
PRIDEiP47929
ProteomicsDBi55824

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		16627, 310 antibodies from 20 providers
652, 168 antibodies from 26 providers

The DNASU plasmid repository

More...DNASUi		653499

Genome annotation databases

EnsembliENST00000314980; ENSP00000313571; ENSG00000178934
ENST00000378626; ENSP00000367891; ENSG00000205076
ENST00000634448; ENSP00000489395; ENSG00000282902
ENST00000634800; ENSP00000489582; ENSG00000283082
GeneIDi3963
653499
KEGGihsa:3963
hsa:653499
MANE-SelectiENST00000314980.5; ENSP00000313571.3; NM_001042507.4; NP_001035972.1
ENST00000378626.5; ENSP00000367891.3; NM_002307.4; NP_002298.1
UCSCiuc002oje.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		3963
653499
DisGeNETi3963
653499

GeneCards: human genes, protein and diseases

More...GeneCardsi		LGALS7
LGALS7B
HGNCiHGNC:6568, LGALS7
HGNC:34447, LGALS7B
HPAiENSG00000178934, Tissue enriched (skin)
ENSG00000205076, Tissue enhanced (esophagus, skin)
MIMi600615, gene
617139, gene
neXtProtiNX_P47929
OpenTargetsiENSG00000178934
ENSG00000205076
PharmGKBiPA162393892
VEuPathDBiHostDB:ENSG00000178934
HostDB:ENSG00000205076

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3587, Eukaryota
GeneTreeiENSGT01040000240531
HOGENOMiCLU_037794_3_3_1
InParanoidiP47929
OMAiLPMGNVR
OrthoDBi1486238at2759
PhylomeDBiP47929
TreeFamiTF315551

Enzyme and pathway databases

PathwayCommonsiP47929
SignaLinkiP47929

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		3963, 6 hits in 956 CRISPR screens
653499, 21 hits in 946 CRISPR screens
EvolutionaryTraceiP47929

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		LGALS7
PharosiP47929, Tbio

Protein Ontology

More...PROi		PR:P47929
RNActiP47929, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000178934, Expressed in skin of abdomen and 86 other tissues
ExpressionAtlasiP47929, baseline and differential
GenevisibleiP47929, HS

Family and domain databases

CDDicd00070, GLECT, 1 hit
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR044156, Galectin-like
IPR030640, Galectin_7
IPR001079, Galectin_CRD
PANTHERiPTHR11346, PTHR11346, 1 hit
PTHR11346:SF107, PTHR11346:SF107, 1 hit
PfamiView protein in Pfam
PF00337, Gal-bind_lectin, 1 hit
SMARTiView protein in SMART
SM00908, Gal-bind_lectin, 1 hit
SM00276, GLECT, 1 hit
SUPFAMiSSF49899, SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51304, GALECTIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLEG7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P47929
Secondary accession number(s): Q6IB87
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: February 23, 2022
This is version 199 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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