UniProtKB - P47875 (CSRP1_RAT)
Protein
Cysteine and glycine-rich protein 1
Gene
Csrp1
Organism
Rattus norvegicus (Rat)
Status
Functioni
Could play a role in neuronal development.
GO - Molecular functioni
- actinin binding Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- structural constituent of muscle Source: GO_Central
GO - Biological processi
- actin cytoskeleton organization Source: GO_Central
- muscle tissue development Source: GO_Central
- nervous system development Source: RGD
- sarcomere organization Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Cysteine and glycine-rich protein 1Alternative name(s): Cysteine-rich protein 1 Short name: CRP Short name: CRP1 |
Gene namesi | Name:Csrp1 Synonyms:Csrp |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 62053, Csrp1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000075718 | 1 – 193 | Cysteine and glycine-rich protein 1Add BLAST | 193 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 81 | PhosphoserineCombined sources | 1 | |
Modified residuei | 84 | N6-acetyllysineBy similarity | 1 | |
Cross-linki | 91 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 112 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 131 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 137 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 161 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 192 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | P47875 |
PaxDbi | P47875 |
PRIDEi | P47875 |
PTM databases
iPTMneti | P47875 |
PhosphoSitePlusi | P47875 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000008937, Expressed in lung and 22 other tissues |
Genevisiblei | P47875, RN |
Interactioni
Subunit structurei
Interacts with ASCC1; ASCC2 AND TRIP4.
By similarityGO - Molecular functioni
- actinin binding Source: GO_Central
Protein-protein interaction databases
IntActi | P47875, 2 interactors |
STRINGi | 10116.ENSRNOP00000011991 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 61 | LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST | 52 | |
Domaini | 119 – 170 | LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST | 52 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 64 – 69 | Nuclear localization signalSequence analysis | 6 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 63 – 78 | Gly-richAdd BLAST | 16 | |
Compositional biasi | 176 – 187 | Gly-richAdd BLAST | 12 |
Keywords - Domaini
LIM domain, RepeatPhylogenomic databases
eggNOGi | KOG1700, Eukaryota |
GeneTreei | ENSGT00940000156777 |
HOGENOMi | CLU_054591_1_0_1 |
InParanoidi | P47875 |
OMAi | CEGHSFH |
OrthoDBi | 1214165at2759 |
PhylomeDBi | P47875 |
TreeFami | TF313758 |
Family and domain databases
InterProi | View protein in InterPro IPR001781, Znf_LIM |
Pfami | View protein in Pfam PF00412, LIM, 2 hits |
SMARTi | View protein in SMART SM00132, LIM, 2 hits |
PROSITEi | View protein in PROSITE PS00478, LIM_DOMAIN_1, 2 hits PS50023, LIM_DOMAIN_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P47875-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNWGGGKKC GVCQKTVYFA EEVQCEGNSF HKSCFLCMVC KKNLDSTTVA
60 70 80 90 100
VHGEEIYCKS CYGKKYGPKG YGYGQGAGTL SMDKGESLGI KHEEAPGHRP
110 120 130 140 150
TTNPNASKFA QKIGGSERCP RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG
160 170 180 190
KGLESTTLAD KDGEIYCKGC YAKNFGPKGF GFGQGAGALV HSE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U09567 mRNA Translation: AAC52157.1 BC062407 mRNA Translation: AAH62407.1 |
PIRi | S53580 |
RefSeqi | NP_058844.1, NM_017148.2 |
Genome annotation databases
Ensembli | ENSRNOT00000011991; ENSRNOP00000011991; ENSRNOG00000008937 |
GeneIDi | 29276 |
KEGGi | rno:29276 |
UCSCi | RGD:62053, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U09567 mRNA Translation: AAC52157.1 BC062407 mRNA Translation: AAH62407.1 |
PIRi | S53580 |
RefSeqi | NP_058844.1, NM_017148.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | P47875, 2 interactors |
STRINGi | 10116.ENSRNOP00000011991 |
PTM databases
iPTMneti | P47875 |
PhosphoSitePlusi | P47875 |
Proteomic databases
jPOSTi | P47875 |
PaxDbi | P47875 |
PRIDEi | P47875 |
Genome annotation databases
Ensembli | ENSRNOT00000011991; ENSRNOP00000011991; ENSRNOG00000008937 |
GeneIDi | 29276 |
KEGGi | rno:29276 |
UCSCi | RGD:62053, rat |
Organism-specific databases
CTDi | 1465 |
RGDi | 62053, Csrp1 |
Phylogenomic databases
eggNOGi | KOG1700, Eukaryota |
GeneTreei | ENSGT00940000156777 |
HOGENOMi | CLU_054591_1_0_1 |
InParanoidi | P47875 |
OMAi | CEGHSFH |
OrthoDBi | 1214165at2759 |
PhylomeDBi | P47875 |
TreeFami | TF313758 |
Miscellaneous databases
PROi | PR:P47875 |
Gene expression databases
Bgeei | ENSRNOG00000008937, Expressed in lung and 22 other tissues |
Genevisiblei | P47875, RN |
Family and domain databases
InterProi | View protein in InterPro IPR001781, Znf_LIM |
Pfami | View protein in Pfam PF00412, LIM, 2 hits |
SMARTi | View protein in SMART SM00132, LIM, 2 hits |
PROSITEi | View protein in PROSITE PS00478, LIM_DOMAIN_1, 2 hits PS50023, LIM_DOMAIN_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CSRP1_RAT | |
Accessioni | P47875Primary (citable) accession number: P47875 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1996 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 132 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |