UniProtKB - P47801 (EMP1_MOUSE)
Protein
Epithelial membrane protein 1
Gene
Emp1
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Epithelial membrane protein 1Short name: EMP-1 Alternative name(s): Tumor-associated membrane protein |
Gene namesi | Name:Emp1 Synonyms:Tmp |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:107941, Emp1 |
Subcellular locationi
Other locations
Plasma Membrane
- plasma membrane Source: MGI
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 1 – 21 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 67 – 87 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 95 – 115 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 137 – 157 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000164654 | 1 – 160 | Epithelial membrane protein 1Add BLAST | 160 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 35 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 43 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 128 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | P47801 |
PeptideAtlasi | P47801 |
PRIDEi | P47801 |
ProteomicsDBi | 277861 |
PTM databases
GlyGeni | P47801, 3 sites |
iPTMneti | P47801 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000030208, Expressed in conjunctival fornix and 259 other tissues |
ExpressionAtlasi | P47801, baseline and differential |
Genevisiblei | P47801, MM |
Interactioni
Protein-protein interaction databases
IntActi | P47801, 1 interactor |
STRINGi | 10090.ENSMUSP00000107538 |
Miscellaneous databases
RNActi | P47801, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the PMP-22/EMP/MP20 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502S028, Eukaryota |
GeneTreei | ENSGT00950000182696 |
HOGENOMi | CLU_138632_0_1_1 |
InParanoidi | P47801 |
OMAi | KSVQAFM |
OrthoDBi | 1218356at2759 |
PhylomeDBi | P47801 |
TreeFami | TF330414 |
Family and domain databases
InterProi | View protein in InterPro IPR003932, EMP_1 IPR004031, PMP22/EMP/MP20/Claudin IPR004032, PMP22_EMP_MP20 |
PANTHERi | PTHR10671:SF6, PTHR10671:SF6, 1 hit |
Pfami | View protein in Pfam PF00822, PMP22_Claudin, 1 hit |
PRINTSi | PR01453, EPMEMFAMILY PR01454, EPMEMPROT1 |
PROSITEi | View protein in PROSITE PS01221, PMP22_1, 1 hit PS01222, PMP22_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P47801-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLVLLAGLFV VHIATAIMLF VSTIANVWMV ADYANASVGL WKNCTGGNCD
60 70 80 90 100
GSLSYGNEDA IKAVQAFMIL SIIFSIISLV VFVFQLFTME KGNRFFLSGS
110 120 130 140 150
TMLVCWLCIL VGVSIYTHHY AHSEGNFNSS SHQGYCFILT WICFCFSFII
160
GILYMVLRKK
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketS4R2U4 | S4R2U4_MOUSE | Epithelial membrane protein 1 | Emp1 | 41 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U25633 mRNA Translation: AAC52968.1 X98403 mRNA Translation: CAA67053.1 X98471 Genomic DNA Translation: CAA67106.1 BC046299 mRNA Translation: AAH46299.1 BC050899 mRNA Translation: AAH50899.1 |
CCDSi | CCDS20647.1 |
PIRi | JC5730 |
RefSeqi | NP_001275556.1, NM_001288627.1 NP_001275557.1, NM_001288628.1 NP_034258.1, NM_010128.4 XP_006505565.1, XM_006505502.1 |
Genome annotation databases
Ensembli | ENSMUST00000032330; ENSMUSP00000032330; ENSMUSG00000030208 ENSMUST00000111907; ENSMUSP00000107538; ENSMUSG00000030208 ENSMUST00000205156; ENSMUSP00000145069; ENSMUSG00000030208 |
GeneIDi | 13730 |
KEGGi | mmu:13730 |
UCSCi | uc009elo.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U25633 mRNA Translation: AAC52968.1 X98403 mRNA Translation: CAA67053.1 X98471 Genomic DNA Translation: CAA67106.1 BC046299 mRNA Translation: AAH46299.1 BC050899 mRNA Translation: AAH50899.1 |
CCDSi | CCDS20647.1 |
PIRi | JC5730 |
RefSeqi | NP_001275556.1, NM_001288627.1 NP_001275557.1, NM_001288628.1 NP_034258.1, NM_010128.4 XP_006505565.1, XM_006505502.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | P47801, 1 interactor |
STRINGi | 10090.ENSMUSP00000107538 |
PTM databases
GlyGeni | P47801, 3 sites |
iPTMneti | P47801 |
Proteomic databases
PaxDbi | P47801 |
PeptideAtlasi | P47801 |
PRIDEi | P47801 |
ProteomicsDBi | 277861 |
Protocols and materials databases
Antibodypediai | 23604, 110 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000032330; ENSMUSP00000032330; ENSMUSG00000030208 ENSMUST00000111907; ENSMUSP00000107538; ENSMUSG00000030208 ENSMUST00000205156; ENSMUSP00000145069; ENSMUSG00000030208 |
GeneIDi | 13730 |
KEGGi | mmu:13730 |
UCSCi | uc009elo.1, mouse |
Organism-specific databases
CTDi | 2012 |
MGIi | MGI:107941, Emp1 |
Phylogenomic databases
eggNOGi | ENOG502S028, Eukaryota |
GeneTreei | ENSGT00950000182696 |
HOGENOMi | CLU_138632_0_1_1 |
InParanoidi | P47801 |
OMAi | KSVQAFM |
OrthoDBi | 1218356at2759 |
PhylomeDBi | P47801 |
TreeFami | TF330414 |
Miscellaneous databases
BioGRID-ORCSi | 13730, 1 hit in 52 CRISPR screens |
ChiTaRSi | Emp1, mouse |
PROi | PR:P47801 |
RNActi | P47801, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030208, Expressed in conjunctival fornix and 259 other tissues |
ExpressionAtlasi | P47801, baseline and differential |
Genevisiblei | P47801, MM |
Family and domain databases
InterProi | View protein in InterPro IPR003932, EMP_1 IPR004031, PMP22/EMP/MP20/Claudin IPR004032, PMP22_EMP_MP20 |
PANTHERi | PTHR10671:SF6, PTHR10671:SF6, 1 hit |
Pfami | View protein in Pfam PF00822, PMP22_Claudin, 1 hit |
PRINTSi | PR01453, EPMEMFAMILY PR01454, EPMEMPROT1 |
PROSITEi | View protein in PROSITE PS01221, PMP22_1, 1 hit PS01222, PMP22_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | EMP1_MOUSE | |
Accessioni | P47801Primary (citable) accession number: P47801 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1996 |
Last sequence update: | November 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 140 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families