UniProtKB - P47317 (ATCL_MYCGE)
Protein
Probable cation-transporting P-type ATPase
Gene
pacL
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Functioni
Could mediate calcium influx.
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 331 | 4-aspartylphosphate intermediateBy similarity | 1 | |
Metal bindingi | 589 | MagnesiumBy similarity | 1 | |
Metal bindingi | 593 | MagnesiumBy similarity | 1 |
GO - Molecular functioni
- ATPase activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- proton-exporting ATPase activity, phosphorylative mechanism Source: GO_Central
Keywordsi
Molecular function | Translocase |
Ligand | ATP-binding, Magnesium, Metal-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | MGEN243273:G1GJ2-83-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:pacL Ordered Locus Names:MG071 |
Organismi | Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) |
Taxonomic identifieri | 243273 [NCBI] |
Taxonomic lineagei | Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 41 | CytoplasmicSequence analysisAdd BLAST | 41 | |
Transmembranei | 42 – 62 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 63 – 79 | ExtracellularSequence analysisAdd BLAST | 17 | |
Transmembranei | 80 – 100 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 101 – 237 | CytoplasmicSequence analysisAdd BLAST | 137 | |
Transmembranei | 238 – 257 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 258 – 275 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 276 – 293 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 294 – 644 | CytoplasmicSequence analysisAdd BLAST | 351 | |
Transmembranei | 645 – 664 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 665 – 687 | ExtracellularSequence analysisAdd BLAST | 23 | |
Transmembranei | 688 – 708 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 709 – 726 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 727 – 749 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 750 – 770 | ExtracellularSequence analysisAdd BLAST | 21 | |
Transmembranei | 771 – 790 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 791 – 803 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 804 – 826 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 827 – 844 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 845 – 865 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 866 – 874 | CytoplasmicSequence analysis | 9 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000046162 | 1 – 874 | Probable cation-transporting P-type ATPaseAdd BLAST | 874 |
Keywords - PTMi
PhosphoproteinFamily & Domainsi
Sequence similaritiesi
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type II subfamily. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0474, Bacteria |
HOGENOMi | CLU_002360_1_1_14 |
OMAi | DPPTPLW |
OrthoDBi | 178322at2 |
Family and domain databases
Gene3Di | 3.40.1110.10, 2 hits 3.40.50.1000, 2 hits |
InterProi | View protein in InterPro IPR006068, ATPase_P-typ_cation-transptr_C IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF00689, Cation_ATPase_C, 1 hit PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01494, ATPase_P-type, 4 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
i Sequence
Sequence statusi: Complete.
P47317-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNSWTGLSEQ AAIKSRQEHG ANFLPEKKAT PFWLLFLQQF KSLVVILLLL
60 70 80 90 100
ASLLSFVVAI VSGLRSNWNF NHDLIIEWVQ PFIILLTVFA NSLIGSIQEF
110 120 130 140 150
KAQKSASALK SLTKSFTRVF RNGELISINV SEVVVGDIIF VDAGDIIPAD
160 170 180 190 200
GKLLQVNNLR CLESFLTGES TPVDKTIDSN EKATILEQTN LVFSGAQVVY
210 220 230 240 250
GSGVFQVEAV GIKTQVGKIA KTVDDSVTKL SPLQQKLEKI GKWFSWFGLG
260 270 280 290 300
LFAVVFLVQT ALLGFDNFTN NWSIALIGAI ALVVAIIPEG LVTFINVIFA
310 320 330 340 350
LSVQKLTKQK AIIKYLSVIE TLGSVQIICT DKTGTLTQNQ MKVVDHFCFN
360 370 380 390 400
STTQTDLARA LCLCNNASIS KDANKTGDPT EIALLEWKDR SQLDLKTYYR
410 420 430 440 450
VYEKAFDSIR KLMTVVVQKD NRFIVIVKGA PDVLLPLCNN VQNEVKNIEN
460 470 480 490 500
LLDQSAGQGL RTLAVALKVL YKFDQNDQKQ IDELENNLEF LGFVSLQDPP
510 520 530 540 550
RKESKEAILA CKKANITPIM ITGDHLKTAT VIAKELGILT LDNQAVLGSE
560 570 580 590 600
LDEKKILDYR VFARVTPQQK LAIVSAWKEA GFTVSVTGDG VNDAPALIKS
610 620 630 640 650
DVGCCMGITG VDIAKDASDL IISDDNFATI VNGIEEGRKT FLTCKRVLLN
660 670 680 690 700
LFLTSIAGTV VVLLGLFILG QVFKTNLLQQ GHDFQVFSPT QLLIINLFVH
710 720 730 740 750
GFPAVALAVQ PVKEKLMVGS FSTKNLFYNR QGFDLIWQSL FLSFLTLLFY
760 770 780 790 800
SLGIIYAINN RDLQTSGDLI NRAGSTCGFF ILGASAALNS LNLMVDKPLL
810 820 830 840 850
MTNPWFFKLV WIGSLASILV FLLIIFINPL GLVFNVLQDL TNHPVLISYS
860 870
FGGVILYMGM NEVVKLIRLG YGNI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L43967 Genomic DNA Translation: AAC71289.1 X61532 Genomic DNA Translation: CAA43744.1 |
PIRi | H64207 |
RefSeqi | WP_009885927.1, NZ_AAGX01000011.1 |
Genome annotation databases
EnsemblBacteriai | AAC71289; AAC71289; MG_071 |
KEGGi | mge:MG_071 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L43967 Genomic DNA Translation: AAC71289.1 X61532 Genomic DNA Translation: CAA43744.1 |
PIRi | H64207 |
RefSeqi | WP_009885927.1, NZ_AAGX01000011.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 243273.MG_071 |
Genome annotation databases
EnsemblBacteriai | AAC71289; AAC71289; MG_071 |
KEGGi | mge:MG_071 |
Phylogenomic databases
eggNOGi | COG0474, Bacteria |
HOGENOMi | CLU_002360_1_1_14 |
OMAi | DPPTPLW |
OrthoDBi | 178322at2 |
Enzyme and pathway databases
BioCyci | MGEN243273:G1GJ2-83-MONOMER |
Family and domain databases
Gene3Di | 3.40.1110.10, 2 hits 3.40.50.1000, 2 hits |
InterProi | View protein in InterPro IPR006068, ATPase_P-typ_cation-transptr_C IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF00689, Cation_ATPase_C, 1 hit PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01494, ATPase_P-type, 4 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ATCL_MYCGE | |
Accessioni | P47317Primary (citable) accession number: P47317 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1996 |
Last sequence update: | February 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families