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Protein

Hexose transporter HXT16

Gene

HXT16

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probable glucose transporter.

GO - Molecular functioni

  • carbohydrate:proton symporter activity Source: GO_Central
  • fructose transmembrane transporter activity Source: SGD
  • glucose transmembrane transporter activity Source: SGD
  • mannose transmembrane transporter activity Source: SGD

GO - Biological processi

Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31768-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Hexose transporter HXT16
Gene namesi
Name:HXT16
Ordered Locus Names:YJR158W
ORF Names:J2260
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

SGDiS000003919 HXT16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 55CytoplasmicSequence analysisAdd BLAST55
Transmembranei56 – 76Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini77 – 112ExtracellularSequence analysisAdd BLAST36
Transmembranei113 – 133Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini134 – 139CytoplasmicSequence analysis6
Transmembranei140 – 160Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini161 – 170ExtracellularSequence analysis10
Transmembranei171 – 191Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini192 – 197CytoplasmicSequence analysis6
Transmembranei198 – 218Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini219 – 232ExtracellularSequence analysisAdd BLAST14
Transmembranei233 – 253Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini254 – 336CytoplasmicSequence analysisAdd BLAST83
Transmembranei337 – 353Helical; Name=7Sequence analysisAdd BLAST17
Topological domaini354 – 359ExtracellularSequence analysis6
Transmembranei360 – 377Helical; Name=8Sequence analysisAdd BLAST18
Topological domaini378 – 384CytoplasmicSequence analysis7
Transmembranei385 – 405Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini406 – 427ExtracellularSequence analysisAdd BLAST22
Transmembranei428 – 448Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini449 – 465CytoplasmicSequence analysisAdd BLAST17
Transmembranei466 – 486Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini487ExtracellularSequence analysis1
Transmembranei488 – 508Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini509 – 567CytoplasmicSequence analysisAdd BLAST59

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504051 – 567Hexose transporter HXT16Add BLAST567

Proteomic databases

PaxDbiP47185
PRIDEiP47185

Interactioni

Protein-protein interaction databases

BioGridi33912, 23 interactors
DIPiDIP-7209N
IntActiP47185, 2 interactors
MINTiP47185
STRINGi4932.YJR158W

Structurei

3D structure databases

ProteinModelPortaliP47185
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00920000149265
HOGENOMiHOG000202870
InParanoidiP47185
KOiK08139
OrthoDBiEOG092C1Q5W

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequencei

Sequence statusi: Complete.

P47185-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASEQSSPEI NADNLNSSAA DVHVQPPGEK EWSDGFYDKE VINGNTPDAP
60 70 80 90 100
KRGFLGYLII YLLCYPVSFG GFLPGWDSGI TAGFINMDNF KMNFGSYKHS
110 120 130 140 150
TGEYYLSNVR MGLLVAMFSV GCSIGGVAFA RLADTLGRRL AIVIVVLVYM
160 170 180 190 200
VGAIIQISSN HKWYQYFVGK IIYGLGAGGC SVLCPMLLSE IAPTDLRGGL
210 220 230 240 250
VSLYQLNMTF GIFLGYCSVY GTRKYSNTAQ WRIPVGLCFL WALIIIVGML
260 270 280 290 300
LVPESPRYLI ECERHEEACV SIAKIDKVSP EDPWVLKQAD EINAGVLAQR
310 320 330 340 350
ELGEASWKEL FSVKTKVLQR LITGILVQTF LQLTGENYFF FYGTTIFKSV
360 370 380 390 400
GLTDGFETSI VLGTVNFFST IIAVMVVDKI GRRKCLLFGA ASMMACMVIF
410 420 430 440 450
ASIGVKCLYP HGQDGPSSKG AGNAMIVFTC FYIFCFATTW APVAYIVVAE
460 470 480 490 500
SFPSKVKSKA MSISTAFNWL WQFLIGFFTP FITGSIHFYY GYVFVGCLVA
510 520 530 540 550
MFLYVFFFLP ETIGLSLEET QLLYEEGIKP WKSASWVPPS RRGASSRETE
560
AKKKSWKEVL KFPKSFN
Length:567
Mass (Da):62,920
Last modified:February 1, 1996 - v1
Checksum:iB9C3C21B97528A4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49658 Genomic DNA Translation: CAA89691.1
BK006943 Genomic DNA Translation: DAA08942.1
PIRiS57187
RefSeqiNP_012692.3, NM_001181816.3

Genome annotation databases

EnsemblFungiiYJR158W; YJR158W; YJR158W
GeneIDi853623
KEGGisce:YJR158W

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49658 Genomic DNA Translation: CAA89691.1
BK006943 Genomic DNA Translation: DAA08942.1
PIRiS57187
RefSeqiNP_012692.3, NM_001181816.3

3D structure databases

ProteinModelPortaliP47185
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33912, 23 interactors
DIPiDIP-7209N
IntActiP47185, 2 interactors
MINTiP47185
STRINGi4932.YJR158W

Proteomic databases

PaxDbiP47185
PRIDEiP47185

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJR158W; YJR158W; YJR158W
GeneIDi853623
KEGGisce:YJR158W

Organism-specific databases

SGDiS000003919 HXT16

Phylogenomic databases

GeneTreeiENSGT00920000149265
HOGENOMiHOG000202870
InParanoidiP47185
KOiK08139
OrthoDBiEOG092C1Q5W

Enzyme and pathway databases

BioCyciYEAST:G3O-31768-MONOMER

Miscellaneous databases

PROiPR:P47185

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiHXT16_YEAST
AccessioniPrimary (citable) accession number: P47185
Secondary accession number(s): D6VWX6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 7, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names
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Main funding by: National Institutes of Health

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