UniProtKB - P46992 (YJR1_YEAST)
Protein
Cell wall protein YJL171C
Gene
YJL171C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 5525 molecules/cell in log phase SD medium.1 Publication
Names & Taxonomyi
Protein namesi | Recommended name: Cell wall protein YJL171C |
Gene namesi | Ordered Locus Names:YJL171C ORF Names:J0512 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000003707, YJL171C |
VEuPathDBi | FungiDB:YJL171C |
Subcellular locationi
Plasma membrane
- Cell membrane 3 Publications; GPI-anchor 3 Publications; Extracellular side 3 Publications
Note: GPI-anchored plasma membrane protein (GPI-PMP).
Cell Wall
- fungal-type cell wall Source: SGD
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
Mitochondrion
- mitochondrion Source: SGD
Plasma Membrane
- plasma membrane Source: SGD
Other locations
- anchored component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000042986 | 20 – 368 | Cell wall protein YJL171CAdd BLAST | 349 | |
PropeptideiPRO_0000406124 | 369 – 396 | Removed in mature formSequence analysisAdd BLAST | 28 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 51 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 99 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 122 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 146 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 174 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 219 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 249 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 267 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 300 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 328 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 346 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Lipidationi | 368 | GPI-anchor amidated asparagineSequence analysis | 1 |
Post-translational modificationi
Extensively N-glycosylated.1 Publication
Keywords - PTMi
Glycoprotein, GPI-anchor, LipoproteinProteomic databases
MaxQBi | P46992 |
PaxDbi | P46992 |
PRIDEi | P46992 |
PTM databases
iPTMneti | P46992 |
Expressioni
Inductioni
Induced in response to cell wall damage.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 33589, 53 interactors |
IntActi | P46992, 2 interactors |
STRINGi | 4932.YJL171C |
Miscellaneous databases
RNActi | P46992, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the PGA52 family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | ENOG502QSTV, Eukaryota |
GeneTreei | ENSGT00940000176743 |
HOGENOMi | CLU_030276_4_0_1 |
InParanoidi | P46992 |
OMAi | TIHDYQG |
Family and domain databases
InterProi | View protein in InterPro IPR018805, YJL171C/Tos1_C IPR018807, YJL171C/Tos1_N |
Pfami | View protein in Pfam PF10287, DUF2401, 1 hit PF10290, DUF2403, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P46992-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLQSIVLSVC MFMLHTVAAS GPQSYQKLDF TNVGFTGSYV DVNKFKDITN
60 70 80 90 100
NESCTCEVGD RVWFSGKNAP LADYLSVHFR GPLKLKQFAF YTSPGFTVNN
110 120 130 140 150
SRSSSDWNRL AYYESSSKTA DNVTFLNHGG EASPCLGNAL SYASSNGTGS
160 170 180 190 200
ASEATVLADG TLISSDQEYI IYSNVSCPKS GYDKGCGVYR SGIPAYYGYG
210 220 230 240 250
GTTKMFLFEF EMPTETEKNS SSIGYYDLPA IWLLNDHIAR TSQYPTNANC
260 270 280 290 300
SCWASGCGEY DIFEAMNGTE KNHLYSTFHT FQGIEDLGTG IQSYGYITRN
310 320 330 340 350
TTGTMKGGVV FDSSGNVVSF ISDATPFNGT VSADTVNDLL AAIPENETYS
360 370 380 390
SQLMSISATA PSTTSKSNGV ALTKMQNGVW YYILAIFTAF TQVVLI
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 366 | K → L in CAA89466 (PubMed:8641269).Curated | 1 | |
Sequence conflicti | 371 | A → R in CAA89466 (PubMed:8641269).Curated | 1 | |
Sequence conflicti | 374 | K → N in CAA89466 (PubMed:8641269).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49446 Genomic DNA Translation: CAA89466.1 BK006943 Genomic DNA Translation: DAA08633.2 |
PIRi | S56954 |
RefSeqi | NP_012364.2, NM_001181604.2 |
Genome annotation databases
EnsemblFungii | YJL171C_mRNA; YJL171C; YJL171C |
GeneIDi | 853268 |
KEGGi | sce:YJL171C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49446 Genomic DNA Translation: CAA89466.1 BK006943 Genomic DNA Translation: DAA08633.2 |
PIRi | S56954 |
RefSeqi | NP_012364.2, NM_001181604.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 33589, 53 interactors |
IntActi | P46992, 2 interactors |
STRINGi | 4932.YJL171C |
PTM databases
iPTMneti | P46992 |
Proteomic databases
MaxQBi | P46992 |
PaxDbi | P46992 |
PRIDEi | P46992 |
Genome annotation databases
EnsemblFungii | YJL171C_mRNA; YJL171C; YJL171C |
GeneIDi | 853268 |
KEGGi | sce:YJL171C |
Organism-specific databases
SGDi | S000003707, YJL171C |
VEuPathDBi | FungiDB:YJL171C |
Phylogenomic databases
eggNOGi | ENOG502QSTV, Eukaryota |
GeneTreei | ENSGT00940000176743 |
HOGENOMi | CLU_030276_4_0_1 |
InParanoidi | P46992 |
OMAi | TIHDYQG |
Miscellaneous databases
PROi | PR:P46992 |
RNActi | P46992, protein |
Family and domain databases
InterProi | View protein in InterPro IPR018805, YJL171C/Tos1_C IPR018807, YJL171C/Tos1_N |
Pfami | View protein in Pfam PF10287, DUF2401, 1 hit PF10290, DUF2403, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YJR1_YEAST | |
Accessioni | P46992Primary (citable) accession number: P46992 Secondary accession number(s): D6VW17 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1996 |
Last sequence update: | September 21, 2011 | |
Last modified: | February 10, 2021 | |
This is version 138 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - SIMILARITY comments
Index of protein domains and families - Yeast chromosome X
Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names