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UniProtKB - P46899 (RL18_BACSU)
Protein
50S ribosomal protein L18
Gene
rplR
Organism
Bacillus subtilis (strain 168)
Status
Functioni
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
UniRule annotationRequired for correct processing of both the 5' and 3' ends of 5S rRNA precursor, which is does in conjunction with ribonuclease M5 (RNase M5, rnmV). Possibly folds the 5S rRNA precursor into the correct conformation, thus acting as a chaperone.
1 PublicationGO - Molecular functioni
- 5S rRNA binding Source: GO_Central
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- rRNA processing Source: UniProtKB-KW
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Chaperone, Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Biological process | rRNA processing |
Enzyme and pathway databases
BioCyci | BSUB:BSU01320-MONOMER |
SABIO-RKi | P46899 |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L18UniRule annotationAlternative name(s): BL16 |
Gene namesi | Name:rplRUniRule annotation Ordered Locus Names:BSU01320 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000131216 | 1 – 120 | 50S ribosomal protein L18Add BLAST | 120 |
Proteomic databases
jPOSTi | P46899 |
PaxDbi | P46899 |
PRIDEi | P46899 |
Interactioni
Subunit structurei
Protein-protein interaction databases
IntActi | P46899, 1 interactor |
STRINGi | 224308.BSU01320 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P46899 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL18 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0256, Bacteria |
InParanoidi | P46899 |
OMAi | NKQIYAQ |
PhylomeDBi | P46899 |
Family and domain databases
HAMAPi | MF_01337_B, Ribosomal_L18_B, 1 hit |
InterProi | View protein in InterPro IPR005484, Ribosomal_L18 IPR004389, Ribosomal_L18_bac-type |
PANTHERi | PTHR12899, PTHR12899, 1 hit |
Pfami | View protein in Pfam PF00861, Ribosomal_L18p, 1 hit |
TIGRFAMsi | TIGR00060, L18_bact, 1 hit |
i Sequence
Sequence statusi: Complete.
P46899-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MITKTSKNAA RLKRHARVRA KLSGTAERPR LNVFRSNKHI YAQIIDDVNG
60 70 80 90 100
VTLASASTLD KDLNVESTGD TSAATKVGEL VAKRAAEKGI SDVVFDRGGY
110 120
LYHGRVKALA DAAREAGLKF
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 37 | N → Y in BAA10982 (PubMed:8969501).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L47971 Genomic DNA Translation: AAB06815.1 D64125 Genomic DNA Translation: BAA10982.1 AL009126 Genomic DNA Translation: CAB11908.2 |
PIRi | D69696 |
RefSeqi | NP_388013.2, NC_000964.3 WP_003225816.1, NZ_JNCM01000029.1 |
Genome annotation databases
EnsemblBacteriai | CAB11908; CAB11908; BSU_01320 |
GeneIDi | 64301970 936785 |
KEGGi | bsu:BSU01320 |
PATRICi | fig|224308.179.peg.135 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L47971 Genomic DNA Translation: AAB06815.1 D64125 Genomic DNA Translation: BAA10982.1 AL009126 Genomic DNA Translation: CAB11908.2 |
PIRi | D69696 |
RefSeqi | NP_388013.2, NC_000964.3 WP_003225816.1, NZ_JNCM01000029.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3J3V | electron microscopy | 13.30 | O | 1-120 | [»] | |
3J9W | electron microscopy | 3.90 | BR | 1-120 | [»] | |
5NJT | electron microscopy | 3.80 | h | 1-120 | [»] | |
6HA1 | electron microscopy | 3.10 | O | 1-120 | [»] | |
6HA8 | electron microscopy | 3.50 | O | 1-120 | [»] | |
6HTQ | electron microscopy | 4.50 | O | 1-120 | [»] | |
6PPF | electron microscopy | 3.40 | O | 1-120 | [»] | |
6PPK | electron microscopy | 4.40 | O | 1-120 | [»] | |
6TNN | electron microscopy | 3.07 | h | 1-120 | [»] | |
6TPQ | electron microscopy | 3.07 | h | 1-120 | [»] | |
7AQC | electron microscopy | 2.99 | O | 1-120 | [»] | |
7AQD | electron microscopy | 3.10 | O | 1-120 | [»] | |
7AS8 | electron microscopy | 2.90 | S | 1-120 | [»] | |
7AS9 | electron microscopy | 3.50 | S | 1-120 | [»] | |
7OPE | electron microscopy | 3.20 | S | 1-120 | [»] | |
SMRi | P46899 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | P46899, 1 interactor |
STRINGi | 224308.BSU01320 |
Proteomic databases
jPOSTi | P46899 |
PaxDbi | P46899 |
PRIDEi | P46899 |
Genome annotation databases
EnsemblBacteriai | CAB11908; CAB11908; BSU_01320 |
GeneIDi | 64301970 936785 |
KEGGi | bsu:BSU01320 |
PATRICi | fig|224308.179.peg.135 |
Phylogenomic databases
eggNOGi | COG0256, Bacteria |
InParanoidi | P46899 |
OMAi | NKQIYAQ |
PhylomeDBi | P46899 |
Enzyme and pathway databases
BioCyci | BSUB:BSU01320-MONOMER |
SABIO-RKi | P46899 |
Family and domain databases
HAMAPi | MF_01337_B, Ribosomal_L18_B, 1 hit |
InterProi | View protein in InterPro IPR005484, Ribosomal_L18 IPR004389, Ribosomal_L18_bac-type |
PANTHERi | PTHR12899, PTHR12899, 1 hit |
Pfami | View protein in Pfam PF00861, Ribosomal_L18p, 1 hit |
TIGRFAMsi | TIGR00060, L18_bact, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL18_BACSU | |
Accessioni | P46899Primary (citable) accession number: P46899 Secondary accession number(s): P70969 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | February 23, 2022 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families