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UniProtKB - P46782 (RS5_HUMAN)

Entry version 207 (02 Jun 2021)
Sequence version 4 (23 Jan 2007)
Previous versions | rss
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Protein

40S ribosomal protein S5

Gene

RPS5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P46782

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNOR Signaling Network Open Resource

More...SIGNORi		P46782

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S5
Alternative name(s):
Small ribosomal subunit protein uS71 Publication
Cleaved into the following chain:
40S ribosomal protein S5, N-terminally processed
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:10426, RPS5

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		603630, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P46782

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000083845.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		6193

Open Targets

More...OpenTargetsi		ENSG00000083845

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA34841

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P46782, Tbio

Chemistry databases

Drug and drug target database

More...DrugBanki		DB11638, Artenimol

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RPS5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003703691 – 20440S ribosomal protein S5Add BLAST204
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved; alternateCombined sources2 Publications
ChainiPRO_00001245262 – 20440S ribosomal protein S5, N-terminally processedAdd BLAST203

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionine; in 40S ribosomal protein S5; alternateCombined sources1 Publication1
Modified residuei2N-acetylthreonine; in 40S ribosomal protein S5, N-terminally processedCombined sources2 Publications1
Modified residuei14PhosphothreonineCombined sources1
Modified residuei47N6-acetyllysine; alternateCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki47Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei142PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P46782

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P46782

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P46782

MaxQB - The MaxQuant DataBase

More...MaxQBi		P46782

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P46782

PeptideAtlas

More...PeptideAtlasi		P46782

PRoteomics IDEntifications database

More...PRIDEi		P46782

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		55764

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P46782

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		P46782

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P46782

MetOSite database of methionine sulfoxide sites

More...MetOSitei		P46782

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P46782

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P46782

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000083845, Expressed in epithelium of bronchus and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P46782, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P46782, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000083845, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		112107, 263 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5223, 40S cytosolic small ribosomal subunit

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P46782

Protein interaction database and analysis system

More...IntActi		P46782, 65 interactors

Molecular INTeraction database

More...MINTi		P46782

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000472985

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P46782, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1204
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P46782

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS7 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3291, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010806

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_063975_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P46782

Database of Orthologous Groups

More...OrthoDBi		1532160at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P46782

TreeFam database of animal gene trees

More...TreeFami		TF300872

Family and domain databases

Conserved Domains Database

More...CDDi		cd14867, uS7_Eukaryote, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.455.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000235, Ribosomal_S5/S7
IPR005716, Ribosomal_S5/S7_euk/arc
IPR020606, Ribosomal_S7_CS
IPR023798, Ribosomal_S7_dom
IPR036823, Ribosomal_S7_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR11205, PTHR11205, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00177, Ribosomal_S7, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002122, RPS7p_RPS7a_RPS5e_RPS7o, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47973, SSF47973, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01028, uS7_euk_arch, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00052, RIBOSOMAL_S7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P46782-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP 
        60         70         80         90        100
HSAGRYAAKR FRKAQCPIVE RLTNSMMMHG RNNGKKLMTV RIVKHAFEII 
       110        120        130        140        150
HLLTGENPLQ VLVNAIINSG PREDSTRIGR AGTVRRQAVD VSPLRRVNQA 
       160        170        180        190        200
IWLLCTGARE AAFRNIKTIA ECLADELINA AKGSSNSYAI KKKDELERVA 

KSNR
Length:204
Mass (Da):22,876
Last modified:January 23, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDFE2FD5AAFCFD894
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R0F0M0R0F0_HUMAN
40S ribosomal protein S5
RPS5
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0R2M0R0R2_HUMAN
40S ribosomal protein S5
RPS5
225Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZN2M0QZN2_HUMAN
40S ribosomal protein S5
RPS5
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti59 – 60KR → NA in AAA85658 (PubMed:7772601).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U14970 mRNA Translation: AAA85658.1
AB061853 Genomic DNA Translation: BAB79493.1
AK311938 mRNA Translation: BAG34879.1
CH471135 Genomic DNA Translation: EAW72581.1
BC015405 mRNA Translation: AAH15405.1
BC018151 mRNA Translation: AAH18151.1
AB007149 Genomic DNA Translation: BAA25815.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12978.1

Protein sequence database of the Protein Information Resource

More...PIRi		S55916

NCBI Reference Sequences

More...RefSeqi		NP_001000.2, NM_001009.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000196551; ENSP00000196551; ENSG00000083845
ENST00000596046; ENSP00000472985; ENSG00000083845
ENST00000601521; ENSP00000470114; ENSG00000083845

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6193

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:6193

UCSC genome browser

More...UCSCi		uc002qsn.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14970 mRNA Translation: AAA85658.1
AB061853 Genomic DNA Translation: BAB79493.1
AK311938 mRNA Translation: BAG34879.1
CH471135 Genomic DNA Translation: EAW72581.1
BC015405 mRNA Translation: AAH15405.1
BC018151 mRNA Translation: AAH18151.1
AB007149 Genomic DNA Translation: BAA25815.1
CCDSiCCDS12978.1
PIRiS55916
RefSeqiNP_001000.2, NM_001009.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SF1-204[»]
4V6Xelectron microscopy5.00AF1-204[»]
5A2Qelectron microscopy3.90F1-204[»]
5AJ0electron microscopy3.50BF1-204[»]
5FLXelectron microscopy3.90F1-204[»]
5LKSelectron microscopy3.60SF1-204[»]
5OA3electron microscopy4.30F1-204[»]
5T2Celectron microscopy3.60As1-204[»]
5VYCX-ray6.00F1/F2/F3/F4/F5/F61-204[»]
6EK0electron microscopy2.90SF1-204[»]
6FECelectron microscopy6.30U14-204[»]
6G18electron microscopy3.60F1-204[»]
6G4Selectron microscopy4.00F1-204[»]
6G4Welectron microscopy4.50F1-204[»]
6G51electron microscopy4.10F1-204[»]
6G53electron microscopy4.50F1-204[»]
6G5Helectron microscopy3.60F1-204[»]
6G5Ielectron microscopy3.50F1-204[»]
6IP5electron microscopy3.902r1-204[»]
6IP6electron microscopy4.502r1-204[»]
6IP8electron microscopy3.902r1-204[»]
6OLEelectron microscopy3.10SF16-204[»]
6OLFelectron microscopy3.90SF16-204[»]
6OLGelectron microscopy3.40BF15-204[»]
6OLIelectron microscopy3.50SF16-204[»]
6OLZelectron microscopy3.90BF15-204[»]
6OM0electron microscopy3.10SF16-204[»]
6OM7electron microscopy3.70SF16-204[»]
6QZPelectron microscopy2.90SF16-204[»]
6XA1electron microscopy2.80SF16-204[»]
6Y0Gelectron microscopy3.20SF1-204[»]
6Y2Lelectron microscopy3.00SF1-204[»]
6Y57electron microscopy3.50SF1-204[»]
6YBSelectron microscopy3.10V1-204[»]
6Z6Lelectron microscopy3.00SF1-204[»]
6Z6Melectron microscopy3.10SF1-204[»]
6Z6Nelectron microscopy2.90SF1-204[»]
6ZLWelectron microscopy2.60K1-204[»]
6ZM7electron microscopy2.70SF1-204[»]
6ZMEelectron microscopy3.00SF1-204[»]
6ZMIelectron microscopy2.60SF1-204[»]
6ZMOelectron microscopy3.10SF1-204[»]
6ZMTelectron microscopy3.00K1-204[»]
6ZMWelectron microscopy3.70V1-204[»]
6ZN5electron microscopy3.20K16-204[»]
6ZOJelectron microscopy2.80F1-204[»]
6ZOLelectron microscopy2.80F1-204[»]
6ZONelectron microscopy3.00e1-204[»]
6ZP4electron microscopy2.90e1-204[»]
6ZVHelectron microscopy2.90F16-204[»]
6ZVJelectron microscopy3.80e16-204[»]
6ZXDelectron microscopy3.20F1-204[»]
6ZXEelectron microscopy3.00F1-204[»]
6ZXFelectron microscopy3.70F1-204[»]
6ZXGelectron microscopy2.60F1-204[»]
6ZXHelectron microscopy2.70F1-204[»]
7A09electron microscopy3.50e1-204[»]
7K5Ielectron microscopy2.90F1-204[»]
SMRiP46782
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi112107, 263 interactors
ComplexPortaliCPX-5223, 40S cytosolic small ribosomal subunit
CORUMiP46782
IntActiP46782, 65 interactors
MINTiP46782
STRINGi9606.ENSP00000472985

Chemistry databases

DrugBankiDB11638, Artenimol

PTM databases

iPTMnetiP46782
MetOSiteiP46782
PhosphoSitePlusiP46782
SwissPalmiP46782

Genetic variation databases

BioMutaiRPS5

2D gel databases

SWISS-2DPAGEiP46782

Proteomic databases

EPDiP46782
jPOSTiP46782
MassIVEiP46782
MaxQBiP46782
PaxDbiP46782
PeptideAtlasiP46782
PRIDEiP46782
ProteomicsDBi55764
TopDownProteomicsiP46782

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33338, 249 antibodies

The DNASU plasmid repository

More...DNASUi		6193

Genome annotation databases

EnsembliENST00000196551; ENSP00000196551; ENSG00000083845
ENST00000596046; ENSP00000472985; ENSG00000083845
ENST00000601521; ENSP00000470114; ENSG00000083845
GeneIDi6193
KEGGihsa:6193
UCSCiuc002qsn.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6193
DisGeNETi6193

GeneCards: human genes, protein and diseases

More...GeneCardsi		RPS5
HGNCiHGNC:10426, RPS5
HPAiENSG00000083845, Low tissue specificity
MIMi603630, gene
neXtProtiNX_P46782
OpenTargetsiENSG00000083845
PharmGKBiPA34841
VEuPathDBiHostDB:ENSG00000083845.8

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3291, Eukaryota
GeneTreeiENSGT00390000010806
HOGENOMiCLU_063975_0_0_1
InParanoidiP46782
OrthoDBi1532160at2759
PhylomeDBiP46782
TreeFamiTF300872

Enzyme and pathway databases

PathwayCommonsiP46782
ReactomeiR-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORiP46782

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		6193, 808 hits in 976 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		RPS5, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		RPS5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		6193
PharosiP46782, Tbio

Protein Ontology

More...PROi		PR:P46782
RNActiP46782, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000083845, Expressed in epithelium of bronchus and 242 other tissues
ExpressionAtlasiP46782, baseline and differential
GenevisibleiP46782, HS

Family and domain databases

CDDicd14867, uS7_Eukaryote, 1 hit
Gene3Di1.10.455.10, 1 hit
InterProiView protein in InterPro
IPR000235, Ribosomal_S5/S7
IPR005716, Ribosomal_S5/S7_euk/arc
IPR020606, Ribosomal_S7_CS
IPR023798, Ribosomal_S7_dom
IPR036823, Ribosomal_S7_dom_sf
PANTHERiPTHR11205, PTHR11205, 1 hit
PfamiView protein in Pfam
PF00177, Ribosomal_S7, 1 hit
PIRSFiPIRSF002122, RPS7p_RPS7a_RPS5e_RPS7o, 1 hit
SUPFAMiSSF47973, SSF47973, 1 hit
TIGRFAMsiTIGR01028, uS7_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS00052, RIBOSOMAL_S7, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46782
Secondary accession number(s): B2R4T2, Q96BN0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: June 2, 2021
This is version 207 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
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