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UniProtKB - P46782 (RS5_HUMAN)

Entry version 196 (16 Oct 2019)
Sequence version 4 (23 Jan 2007)
Previous versions | rss
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Protein

40S ribosomal protein S5

Gene

RPS5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S5
Alternative name(s):
Small ribosomal subunit protein uS71 Publication
Cleaved into the following chain:
40S ribosomal protein S5, N-terminally processed
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:10426 RPS5

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		603630 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P46782

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		6193

Open Targets

More...OpenTargetsi		ENSG00000083845

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA34841

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P46782

Chemistry databases

Drug and drug target database

More...DrugBanki		DB11638 Artenimol

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RPS5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003703691 – 20440S ribosomal protein S5Add BLAST204
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved; alternateCombined sources2 Publications
ChainiPRO_00001245262 – 20440S ribosomal protein S5, N-terminally processedAdd BLAST203

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionine; in 40S ribosomal protein S5; alternateCombined sources1 Publication1
Modified residuei2N-acetylthreonine; in 40S ribosomal protein S5, N-terminally processedCombined sources2 Publications1
Modified residuei14PhosphothreonineCombined sources1
Modified residuei47N6-acetyllysine; alternateCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki47Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei142PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P46782

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P46782

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P46782

MaxQB - The MaxQuant DataBase

More...MaxQBi		P46782

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P46782

PeptideAtlas

More...PeptideAtlasi		P46782

PRoteomics IDEntifications database

More...PRIDEi		P46782

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		55764

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P46782

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		P46782

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P46782

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P46782

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P46782

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000083845 Expressed in 231 organ(s), highest expression level in epithelium of bronchus

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P46782 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P46782 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA055878
HPA061979

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		112107, 217 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P46782

Protein interaction database and analysis system

More...IntActi		P46782, 49 interactors

Molecular INTeraction database

More...MINTi		P46782

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000472985

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P46782

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS7 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3291 Eukaryota
COG0049 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010806

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000039066

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P46782

KEGG Orthology (KO)

More...KOi		K02989

Database of Orthologous Groups

More...OrthoDBi		1532160at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P46782

TreeFam database of animal gene trees

More...TreeFami		TF300872

Family and domain databases

Conserved Domains Database

More...CDDi		cd14867 uS7_Eukaryote, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.455.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000235 Ribosomal_S5/S7
IPR005716 Ribosomal_S5/S7_euk/arc
IPR020606 Ribosomal_S7_CS
IPR023798 Ribosomal_S7_dom
IPR036823 Ribosomal_S7_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR11205 PTHR11205, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00177 Ribosomal_S7, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002122 RPS7p_RPS7a_RPS5e_RPS7o, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47973 SSF47973, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01028 uS7_euk_arch, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00052 RIBOSOMAL_S7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P46782-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP 
        60         70         80         90        100
HSAGRYAAKR FRKAQCPIVE RLTNSMMMHG RNNGKKLMTV RIVKHAFEII 
       110        120        130        140        150
HLLTGENPLQ VLVNAIINSG PREDSTRIGR AGTVRRQAVD VSPLRRVNQA 
       160        170        180        190        200
IWLLCTGARE AAFRNIKTIA ECLADELINA AKGSSNSYAI KKKDELERVA 

KSNR
Length:204
Mass (Da):22,876
Last modified:January 23, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDFE2FD5AAFCFD894
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R0F0M0R0F0_HUMAN
40S ribosomal protein S5
RPS5
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0R2M0R0R2_HUMAN
40S ribosomal protein S5
RPS5
225Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZN2M0QZN2_HUMAN
40S ribosomal protein S5
RPS5
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti59 – 60KR → NA in AAA85658 (PubMed:7772601).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U14970 mRNA Translation: AAA85658.1
AB061853 Genomic DNA Translation: BAB79493.1
AK311938 mRNA Translation: BAG34879.1
CH471135 Genomic DNA Translation: EAW72581.1
BC015405 mRNA Translation: AAH15405.1
BC018151 mRNA Translation: AAH18151.1
AB007149 Genomic DNA Translation: BAA25815.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12978.1

Protein sequence database of the Protein Information Resource

More...PIRi		S55916

NCBI Reference Sequences

More...RefSeqi		NP_001000.2, NM_001009.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000196551; ENSP00000196551; ENSG00000083845
ENST00000596046; ENSP00000472985; ENSG00000083845
ENST00000601521; ENSP00000470114; ENSG00000083845

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6193

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:6193

UCSC genome browser

More...UCSCi		uc002qsn.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14970 mRNA Translation: AAA85658.1
AB061853 Genomic DNA Translation: BAB79493.1
AK311938 mRNA Translation: BAG34879.1
CH471135 Genomic DNA Translation: EAW72581.1
BC015405 mRNA Translation: AAH15405.1
BC018151 mRNA Translation: AAH18151.1
AB007149 Genomic DNA Translation: BAA25815.1
CCDSiCCDS12978.1
PIRiS55916
RefSeqiNP_001000.2, NM_001009.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SF1-204[»]
4V6Xelectron microscopy5.00AF1-204[»]
5A2Qelectron microscopy3.90F1-204[»]
5AJ0electron microscopy3.50BF1-204[»]
5FLXelectron microscopy3.90F1-204[»]
5LKSelectron microscopy3.60SF1-204[»]
5OA3electron microscopy4.30F1-204[»]
5T2Celectron microscopy3.60As1-204[»]
5VYCX-ray6.00F1/F2/F3/F4/F5/F61-204[»]
6EK0electron microscopy2.90SF1-204[»]
6FECelectron microscopy6.30U14-204[»]
6G18electron microscopy3.60F1-204[»]
6G4Selectron microscopy4.00F1-204[»]
6G4Welectron microscopy4.50F1-204[»]
6G51electron microscopy4.10F1-204[»]
6G53electron microscopy4.50F1-204[»]
6G5Helectron microscopy3.60F1-204[»]
6G5Ielectron microscopy3.50F1-204[»]
6IP5electron microscopy3.902r1-204[»]
6IP6electron microscopy4.502r1-204[»]
6IP8electron microscopy3.902r1-204[»]
6OLEelectron microscopy3.10SF16-204[»]
6OLFelectron microscopy3.90SF16-204[»]
6OLGelectron microscopy3.40BF15-204[»]
6OLIelectron microscopy3.50SF16-204[»]
6OLZelectron microscopy3.90BF15-204[»]
6OM0electron microscopy3.10SF16-204[»]
6OM7electron microscopy3.70SF16-204[»]
6QZPelectron microscopy2.90SF16-204[»]
SMRiP46782
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi112107, 217 interactors
CORUMiP46782
IntActiP46782, 49 interactors
MINTiP46782
STRINGi9606.ENSP00000472985

Chemistry databases

DrugBankiDB11638 Artenimol

PTM databases

iPTMnetiP46782
PhosphoSitePlusiP46782
SwissPalmiP46782

Polymorphism and mutation databases

BioMutaiRPS5

2D gel databases

SWISS-2DPAGEiP46782

Proteomic databases

EPDiP46782
jPOSTiP46782
MassIVEiP46782
MaxQBiP46782
PaxDbiP46782
PeptideAtlasiP46782
PRIDEiP46782
ProteomicsDBi55764
TopDownProteomicsiP46782

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		6193

Genome annotation databases

EnsembliENST00000196551; ENSP00000196551; ENSG00000083845
ENST00000596046; ENSP00000472985; ENSG00000083845
ENST00000601521; ENSP00000470114; ENSG00000083845
GeneIDi6193
KEGGihsa:6193
UCSCiuc002qsn.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6193
DisGeNETi6193

GeneCards: human genes, protein and diseases

More...GeneCardsi		RPS5
HGNCiHGNC:10426 RPS5
HPAiHPA055878
HPA061979
MIMi603630 gene
neXtProtiNX_P46782
OpenTargetsiENSG00000083845
PharmGKBiPA34841

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3291 Eukaryota
COG0049 LUCA
GeneTreeiENSGT00390000010806
HOGENOMiHOG000039066
InParanoidiP46782
KOiK02989
OrthoDBi1532160at2759
PhylomeDBiP46782
TreeFamiTF300872

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		RPS5 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		RPS5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		6193
PharosiP46782

Protein Ontology

More...PROi		PR:P46782

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000083845 Expressed in 231 organ(s), highest expression level in epithelium of bronchus
ExpressionAtlasiP46782 baseline and differential
GenevisibleiP46782 HS

Family and domain databases

CDDicd14867 uS7_Eukaryote, 1 hit
Gene3Di1.10.455.10, 1 hit
InterProiView protein in InterPro
IPR000235 Ribosomal_S5/S7
IPR005716 Ribosomal_S5/S7_euk/arc
IPR020606 Ribosomal_S7_CS
IPR023798 Ribosomal_S7_dom
IPR036823 Ribosomal_S7_dom_sf
PANTHERiPTHR11205 PTHR11205, 1 hit
PfamiView protein in Pfam
PF00177 Ribosomal_S7, 1 hit
PIRSFiPIRSF002122 RPS7p_RPS7a_RPS5e_RPS7o, 1 hit
SUPFAMiSSF47973 SSF47973, 1 hit
TIGRFAMsiTIGR01028 uS7_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS00052 RIBOSOMAL_S7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46782
Secondary accession number(s): B2R4T2, Q96BN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: October 16, 2019
This is version 196 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
UniProt is an ELIXIR core data resource
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