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Entry version 167 (16 Oct 2019)
Sequence version 3 (27 Jul 2011)
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Protein

Unconventional myosin-Ib

Gene

Myo1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport.

Caution

Represents an unconventional myosin. This protein should not be confused with the conventional myosin-1 (MYH1).Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi108 – 115ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Calmodulin-binding, Motor protein, Myosin
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Unconventional myosin-Ib
Alternative name(s):
MIH-L
Myosin I alpha
Short name:
MMI-alpha
Short name:
MMIa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Myo1b
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:107752 Myo1b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001234431 – 1107Unconventional myosin-IbAdd BLAST1107

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei60PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki287Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki287Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P46735

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P46735

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P46735

PeptideAtlas

More...
PeptideAtlasi
P46735

PRoteomics IDEntifications database

More...
PRIDEi
P46735

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P46735

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P46735

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P46735

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Prominent expression is seen in the brain, lung and liver. It is also expressed in the heart and testis. A high level expression is seen in virtually all neurons (but not glia) in the postnatal and adult mouse brain and in neuroblasts of the cerebellar external granular layer.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000018417 Expressed in 283 organ(s), highest expression level in brain blood vessel

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P46735 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P46735 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
201663, 3 interactors

Protein interaction database and analysis system

More...
IntActi
P46735, 8 interactors

Molecular INTeraction database

More...
MINTi
P46735

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000018561

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P46735

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini15 – 701Myosin motorPROSITE-ProRule annotationAdd BLAST687
Domaini704 – 727IQ 1PROSITE-ProRule annotationAdd BLAST24
Domaini728 – 749IQ 2PROSITE-ProRule annotationAdd BLAST22
Domaini750 – 778IQ 3PROSITE-ProRule annotationAdd BLAST29
Domaini780 – 807IQ 4PROSITE-ProRule annotationAdd BLAST28
Domaini808 – 837IQ 5PROSITE-ProRule annotationAdd BLAST30
Domaini923 – 1107TH1PROSITE-ProRule annotationAdd BLAST185

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni592 – 599Actin-bindingSequence analysis8

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0164 Eukaryota
COG5022 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155752

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000260264

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P46735

KEGG Orthology (KO)

More...
KOi
K10356

Database of Orthologous Groups

More...
OrthoDBi
122881at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01378 MYSc_Myo1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR010926 Myosin_TH1
IPR036072 MYSc_Myo1
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00612 IQ, 2 hits
PF00063 Myosin_head, 1 hit
PF06017 Myosin_TH1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193 MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00015 IQ, 5 hits
SM00242 MYSc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096 IQ, 4 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS51757 TH1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P46735-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAKMEVKSSL LDNMIGVGDM VLLEPLNEET FIDNLKKRFD HNEIYTYIGS
60 70 80 90 100
VVISVNPYRS LPIYSPEKVE DYRNRNFYEL SPHIFALSDE AYRSLRDQDK
110 120 130 140 150
DQCILITGES GAGKTEASKL VMSYVAAVCG KGAEVNQVKE QLLQSNPVLE
160 170 180 190 200
AFGNAKTVRN DNSSRFGKYM DIEFDFKGDP LGGVISNYLL EKSRVVKQPR
210 220 230 240 250
GERNFHVFYQ LLSGASEELL YKLKLERDFS RYNYLSLDSA KVNGVDDAAN
260 270 280 290 300
FRTVRNAMQI VGFLDHEAEA VLEVVAAVLK LGNIEFKPES RVNGLDESKI
310 320 330 340 350
KDKNELKEIC ELTSIDQVVL ERAFSFRTVE AKQEKVSTTL NVAQAYYARD
360 370 380 390 400
ALAKNLYSRL FSWLVNRINE SIKAQTKVRK KVMGVLDIYG FEIFEDNSFE
410 420 430 440 450
QFIINYCNEK LQQIFIELTL KEEQEEYIRE DIEWTHIDYF NNAIICDLIE
460 470 480 490 500
NNTNGILAML DEECLRPGTV TDETFLEKLN QVCATHQHFE SRMSKCSRFL
510 520 530 540 550
NDTTLPHSCF RIQHYAGKVL YQVEGFVDKN NDLLYRDLSQ AMWKAGHSLI
560 570 580 590 600
KSLFPEGNPA KVNLKRPPTA GSQFKASVAT LMRNLQTKNP NYIRCIKPND
610 620 630 640 650
KKAAHIFNES LVCHQIRYLG LLENVRVRRA GYAFRQAYEP CLERYKMLCK
660 670 680 690 700
QTWPHWKGPA RSGVEVLFNE LEIPVEEHSF GRSKIFIRNP RTLFQLEDLR
710 720 730 740 750
KQRLEDLATL IQKIYRGWKC RTHFLLMKRS QVVIAAWYRR YAQQKRYQQI
760 770 780 790 800
KSSALVIQSY IRGWKARKIL RELKHQKRCK EAATTIAAYW HGTQARRELK
810 820 830 840 850
RLKEEARRKH AVAVIWAYWL GLKVRREYRK FFRANAGKKI YEFTLQRIVQ
860 870 880 890 900
KYLLEMKNKM PSLSPIDKNW PSRPYLFLDS THKELKRIFH LWRCKKYRDQ
910 920 930 940 950
FTDQQKLIYE EKLEASELFK DKKALYPSSV GQPFQGAYLE INKNPKYKKL
960 970 980 990 1000
KDAIEEKIII AEVVNKINRA NGKSTSRIFL LTNNNLLLAD QKSGQIKSEV
1010 1020 1030 1040 1050
PLVDVTKVSM SSQNDGFFAV HLKEGSEAAS KGDFLFSSDH LIEMATKLYR
1060 1070 1080 1090 1100
TTLSQTKQKL NIEISDEFLV QFRQDKVCVK FIQGNQKNGS VPTCKRKNNR

LLEVAVP
Length:1,107
Mass (Da):128,564
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i42B339708CA9B7E6
GO
Isoform 2 (identifier: P46735-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     791-819: Missing.

Show »
Length:1,078
Mass (Da):125,022
Checksum:iDDC6FAC4197C80ED
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7TQD7Q7TQD7_MOUSE
Myo1b protein
Myo1b
1,136Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YV80D3YV80_MOUSE
Unconventional myosin-Ib
Myo1b
299Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QNH6E9QNH6_MOUSE
Unconventional myosin-Ib
Myo1b
1,078Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q580E9Q580_MOUSE
Unconventional myosin-Ib
Myo1b
1,084Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti44I → R in CAA49604 (PubMed:8458427).Curated1
Sequence conflicti260I → Y in CAA49604 (PubMed:8458427).Curated1
Sequence conflicti304N → I in AAA39800 (PubMed:8449986).Curated1
Sequence conflicti307 – 317KEICELTSIDQ → NEKFASRPASVK in AAA39800 (PubMed:8449986).CuratedAdd BLAST11
Sequence conflicti333Q → R in AAA39800 (PubMed:8449986).Curated1
Sequence conflicti546G → D in AAA39800 (PubMed:8449986).Curated1
Sequence conflicti570 – 571AG → RS in CAA49604 (PubMed:8458427).Curated2
Sequence conflicti742A → E in CAA49604 (PubMed:8458427).Curated1
Sequence conflicti809 – 810KH → ND in CAA49604 (PubMed:8458427).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_003347791 – 819Missing in isoform 2. 1 PublicationAdd BLAST29

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L00923 mRNA Translation: AAA39800.1
AK141207 mRNA Translation: BAE24587.1
CH466548 Genomic DNA Translation: EDK99961.1
BC046300 mRNA Translation: AAH46300.1
X69987 mRNA Translation: CAA49604.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14942.1 [P46735-1]
CCDS69887.1 [P46735-2]

Protein sequence database of the Protein Information Resource

More...
PIRi
A45438

NCBI Reference Sequences

More...
RefSeqi
NP_034993.2, NM_010863.4 [P46735-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000046390; ENSMUSP00000040447; ENSMUSG00000018417 [P46735-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
17912

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:17912

UCSC genome browser

More...
UCSCi
uc007axr.3 mouse [P46735-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L00923 mRNA Translation: AAA39800.1
AK141207 mRNA Translation: BAE24587.1
CH466548 Genomic DNA Translation: EDK99961.1
BC046300 mRNA Translation: AAH46300.1
X69987 mRNA Translation: CAA49604.1
CCDSiCCDS14942.1 [P46735-1]
CCDS69887.1 [P46735-2]
PIRiA45438
RefSeqiNP_034993.2, NM_010863.4 [P46735-1]

3D structure databases

SMRiP46735
ModBaseiSearch...

Protein-protein interaction databases

BioGridi201663, 3 interactors
IntActiP46735, 8 interactors
MINTiP46735
STRINGi10090.ENSMUSP00000018561

PTM databases

iPTMnetiP46735
PhosphoSitePlusiP46735
SwissPalmiP46735

Proteomic databases

jPOSTiP46735
MaxQBiP46735
PaxDbiP46735
PeptideAtlasiP46735
PRIDEiP46735

Genome annotation databases

EnsembliENSMUST00000046390; ENSMUSP00000040447; ENSMUSG00000018417 [P46735-1]
GeneIDi17912
KEGGimmu:17912
UCSCiuc007axr.3 mouse [P46735-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
4430
MGIiMGI:107752 Myo1b

Phylogenomic databases

eggNOGiKOG0164 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00940000155752
HOGENOMiHOG000260264
InParanoidiP46735
KOiK10356
OrthoDBi122881at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Myo1b mouse

Protein Ontology

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PROi
PR:P46735

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000018417 Expressed in 283 organ(s), highest expression level in brain blood vessel
ExpressionAtlasiP46735 baseline and differential
GenevisibleiP46735 MM

Family and domain databases

CDDicd01378 MYSc_Myo1, 1 hit
Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR010926 Myosin_TH1
IPR036072 MYSc_Myo1
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00612 IQ, 2 hits
PF00063 Myosin_head, 1 hit
PF06017 Myosin_TH1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00015 IQ, 5 hits
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50096 IQ, 4 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS51757 TH1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYO1B_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46735
Secondary accession number(s): P70244, Q80VD8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 27, 2011
Last modified: October 16, 2019
This is version 167 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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