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UniProtKB - P46686 (TULP2_MOUSE)

Entry version 132 (02 Dec 2020)
Sequence version 3 (09 Jan 2007)
Previous versions | rss
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Protein

Tubby-related protein 2

Gene

Tulp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Was originally thought to be a phosphodiesterase on the basis of spurious sequence similarities.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tubby-related protein 2
Alternative name(s):
Protein P4-6
Tubby-like protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tulp2
Synonyms:Pdet
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1861600, Tulp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001864691 – 562Tubby-related protein 2Add BLAST562

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei152PhosphoserineCombined sources1
Modified residuei153PhosphoserineCombined sources1
Modified residuei155PhosphoserineCombined sources1
Modified residuei211PhosphothreonineCombined sources1
Modified residuei213PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P46686

PRoteomics IDEntifications database

More...PRIDEi		P46686

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P46686

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P46686

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in retina and testis.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000023467, Expressed in testis and 34 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P46686, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000103391

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P46686, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P46686

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TUB family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2502, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161908

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_028236_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P46686

Identification of Orthologs from Complete Genome Data

More...OMAi		WLWRSCL

TreeFam database of animal gene trees

More...TreeFami		TF314076

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.20.90.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025659, Tubby-like_C
IPR000007, Tubby_C
IPR018066, Tubby_C_CS
IPR005398, Tubby_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01167, Tub, 1 hit
PF16322, Tub_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01573, SUPERTUBBY
PR01574, TUBBYPROTEIN

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54518, SSF54518, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01200, TUB_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P46686-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDREGPRGPR SGASQENEQW KKETLEDEFS GVRLQKLEQQ RQLFEKKQRR 
        60         70         80         90        100
KRQEPLMVQA NPDATLRHRR PRRGEERFQS DSSWGLGVGS PFLQENVPQA 
       110        120        130        140        150
HLPSGAHSAL VTMSYVADGS GERAPLLSPR GAVYTRGNGP AVRHHLCWLP 
       160        170        180        190        200
DSSDSDVEEV TMEDIPVISR PPQTNLANLR RGWLASPGPG ISQEEKEEEV 
       210        220        230        240        250
GSTDARVEDK TPSPDPDPDP TVNSDGDHGD LAPCKVEENT AQKNTETASG 
       260        270        280        290        300
IGDEDREKGE VTESTETNYA PVASKVLQGD DGDASNHNAW NMTCPQPRIP 
       310        320        330        340        350
GPRLGEDMEA YVLLPAPRDH MVQCRIVRNK HGMDKGMFPS YYLYLEAEDG 
       360        370        380        390        400
VAHFLLAGRK RKRSKTSNYL ISLDPKDMSR NGSNFVGKVR SNVLGTKFTI 
       410        420        430        440        450
FDNGVNPERS YWVPDSARIR EELGVVCYET NVLGFRGPRK MTVILPGMDS 
       460        470        480        490        500
RKQRMKVQPQ NDQDSILSRV QKGAGHGLLL LQNKAPSWSD ESGAYVLNFH 
       510        520        530        540        550
GRVTRASVKN FQIVHPDEPD HLVLQFGRVA PNIFTMDFRY PLCPLQAFAI 
       560 
CLSSFDGKLA FF
Length:562
Mass (Da):62,724
Last modified:January 9, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0FD479941D6F7144
GO
Isoform 2 (identifier: P46686-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     561-562: FF → CE

Show »
Length:562
Mass (Da):62,662
Checksum:i0D0309941D6F7144
GO
Isoform 3 (identifier: P46686-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-112: Missing.
     561-562: FF → CE

Show »
Length:450
Mass (Da):49,751
Checksum:i3F03450C613DD435
GO
Isoform 4 (identifier: P46686-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-112: Missing.
     121-132: Missing.
     561-562: FF → CE

Show »
Length:438
Mass (Da):48,545
Checksum:iEB0B0594D137C4BE
GO
Isoform 5 (identifier: P46686-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-112: Missing.
     561-562: Missing.

Show »
Length:448
Mass (Da):49,519
Checksum:iB50C613DD4356ABE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z0R4D3Z0R4_MOUSE
Tubby-like protein
Tulp2
457Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GRN6A0A1B0GRN6_MOUSE
Tubby-related protein 2
Tulp2
457Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GSC0A0A1B0GSC0_MOUSE
Tubby-related protein 2
Tulp2
192Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GR36A0A1B0GR36_MOUSE
Tubby-related protein 2
Tulp2
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD38452 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC36686 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAA49481 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1M → R in AAD38452 (Ref. 1) Curated1
Sequence conflicti314L → V in CAA49481 (PubMed:7509194).Curated1
Sequence conflicti324C → W in AAD38452 (Ref. 1) Curated1
Sequence conflicti324C → W in CAA49481 (PubMed:7509194).Curated1
Sequence conflicti347A → G in AAD38452 (Ref. 1) Curated1
Sequence conflicti347A → G in CAA49481 (PubMed:7509194).Curated1
Sequence conflicti504T → S in CAA49481 (PubMed:7509194).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0221971 – 112Missing in isoform 3, isoform 4 and isoform 5. 2 PublicationsAdd BLAST112
Alternative sequenceiVSP_022198121 – 132Missing in isoform 4. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_022199561 – 562FF → CE in isoform 2, isoform 3 and isoform 4. 4 Publications2
Alternative sequenceiVSP_022200561 – 562Missing in isoform 5. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF105712 mRNA Translation: AAD38452.1 Different initiation.
AK077200 mRNA Translation: BAC36678.1
AK077211 mRNA Translation: BAC36686.1 Different initiation.
AK161165 mRNA Translation: BAE36223.1
BC089545 mRNA Translation: AAH89545.1
X69827 mRNA Translation: CAA49481.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS39953.1 [P46686-1]
CCDS39954.1 [P46686-2]
CCDS71960.1 [P46686-3]
CCDS80720.1 [P46686-4]

NCBI Reference Sequences

More...RefSeqi		NP_001039020.1, NM_001045555.2 [P46686-1]
NP_001277927.1, NM_001290998.2 [P46686-4]
NP_001277928.1, NM_001290999.2 [P46686-3]
NP_032833.2, NM_008807.3 [P46686-2]
XP_006541088.1, XM_006541025.3 [P46686-5]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000024233; ENSMUSP00000024233; ENSMUSG00000023467 [P46686-2]
ENSMUST00000085331; ENSMUSP00000082438; ENSMUSG00000023467 [P46686-4]
ENSMUST00000107759; ENSMUSP00000103388; ENSMUSG00000023467 [P46686-3]
ENSMUST00000107762; ENSMUSP00000103391; ENSMUSG00000023467 [P46686-1]
ENSMUST00000210868; ENSMUSP00000147710; ENSMUSG00000023467 [P46686-5]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56734

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:56734

UCSC genome browser

More...UCSCi		uc009gvk.2, mouse [P46686-3]
uc009gvp.2, mouse [P46686-2]
uc009gvq.2, mouse [P46686-1]
uc009gvr.2, mouse [P46686-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF105712 mRNA Translation: AAD38452.1 Different initiation.
AK077200 mRNA Translation: BAC36678.1
AK077211 mRNA Translation: BAC36686.1 Different initiation.
AK161165 mRNA Translation: BAE36223.1
BC089545 mRNA Translation: AAH89545.1
X69827 mRNA Translation: CAA49481.1 Different initiation.
CCDSiCCDS39953.1 [P46686-1]
CCDS39954.1 [P46686-2]
CCDS71960.1 [P46686-3]
CCDS80720.1 [P46686-4]
RefSeqiNP_001039020.1, NM_001045555.2 [P46686-1]
NP_001277927.1, NM_001290998.2 [P46686-4]
NP_001277928.1, NM_001290999.2 [P46686-3]
NP_032833.2, NM_008807.3 [P46686-2]
XP_006541088.1, XM_006541025.3 [P46686-5]

3D structure databases

SMRiP46686
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103391

PTM databases

iPTMnetiP46686
PhosphoSitePlusiP46686

Proteomic databases

PaxDbiP46686
PRIDEiP46686

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31829, 179 antibodies

Genome annotation databases

EnsembliENSMUST00000024233; ENSMUSP00000024233; ENSMUSG00000023467 [P46686-2]
ENSMUST00000085331; ENSMUSP00000082438; ENSMUSG00000023467 [P46686-4]
ENSMUST00000107759; ENSMUSP00000103388; ENSMUSG00000023467 [P46686-3]
ENSMUST00000107762; ENSMUSP00000103391; ENSMUSG00000023467 [P46686-1]
ENSMUST00000210868; ENSMUSP00000147710; ENSMUSG00000023467 [P46686-5]
GeneIDi56734
KEGGimmu:56734
UCSCiuc009gvk.2, mouse [P46686-3]
uc009gvp.2, mouse [P46686-2]
uc009gvq.2, mouse [P46686-1]
uc009gvr.2, mouse [P46686-4]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7288
MGIiMGI:1861600, Tulp2

Phylogenomic databases

eggNOGiKOG2502, Eukaryota
GeneTreeiENSGT00940000161908
HOGENOMiCLU_028236_0_0_1
InParanoidiP46686
OMAiWLWRSCL
TreeFamiTF314076

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		56734, 1 hit in 12 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Tulp2, mouse

Protein Ontology

More...PROi		PR:P46686
RNActiP46686, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000023467, Expressed in testis and 34 other tissues
GenevisibleiP46686, MM

Family and domain databases

Gene3Di3.20.90.10, 1 hit
InterProiView protein in InterPro
IPR025659, Tubby-like_C
IPR000007, Tubby_C
IPR018066, Tubby_C_CS
IPR005398, Tubby_N
PfamiView protein in Pfam
PF01167, Tub, 1 hit
PF16322, Tub_N, 1 hit
PRINTSiPR01573, SUPERTUBBY
PR01574, TUBBYPROTEIN
SUPFAMiSSF54518, SSF54518, 1 hit
PROSITEiView protein in PROSITE
PS01200, TUB_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTULP2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46686
Secondary accession number(s): Q3TTV1
, Q5FW93, Q8C5R7, Q8C5R9, Q9R1I8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 9, 2007
Last modified: December 2, 2020
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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