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Protein

Ankyrin repeat-containing protein YAR1

Gene

YAR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for normal rate of cell proliferation.

Miscellaneous

Present with 13100 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • unfolded protein binding Source: SGD

GO - Biological processi

  • cellular response to oxidative stress Source: SGD
  • regulation of protein localization Source: SGD
  • response to osmotic stress Source: SGD
  • ribosomal small subunit biogenesis Source: SGD
  • ribosomal small subunit export from nucleus Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34125-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat-containing protein YAR1
Gene namesi
Name:YAR1
Ordered Locus Names:YPL239W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL239W
SGDiS000006160 YAR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000670791 – 200Ankyrin repeat-containing protein YAR1Add BLAST200

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei78PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP46683
PaxDbiP46683
PRIDEiP46683

PTM databases

iPTMnetiP46683

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RPS3P057502EBI-20829,EBI-16140

GO - Molecular functioni

  • unfolded protein binding Source: SGD

Protein-protein interaction databases

BioGridi35924, 240 interactors
IntActiP46683, 13 interactors
MINTiP46683
STRINGi4932.YPL239W

Structurei

Secondary structure

1200
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi10 – 22Combined sources13
Helixi25 – 34Combined sources10
Helixi38 – 43Combined sources6
Turni47 – 49Combined sources3
Helixi53 – 59Combined sources7
Helixi63 – 76Combined sources14
Helixi79 – 86Combined sources8
Helixi96 – 102Combined sources7
Helixi106 – 114Combined sources9
Helixi130 – 136Combined sources7
Helixi140 – 149Combined sources10

3D structure databases

ProteinModelPortaliP46683
SMRiP46683
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati49 – 78ANK 1Add BLAST30
Repeati92 – 121ANK 2Add BLAST30

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

HOGENOMiHOG000111159
InParanoidiP46683
KOiK06867
OMAiSTCLHMA
OrthoDBiEOG092C55QM

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits

Sequencei

Sequence statusi: Complete.

P46683-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLHSEPLDQ EDQDTIILDA RAGDLDSLKD IFTTLVSPEL LSTCKESESD
60 70 80 90 100
STALHMAAAN GHIETVRYIL ETVSRANSAE DLKAFVNEVN KTGNTALHWA
110 120 130 140 150
SLNGKLDVVK LLCDEYEADP FIRNKFGHDA IFEAENSGKE EVETYFLKKY
160 170 180 190 200
DVEPEDDEED TQTEGKNSVQ ITKGTEIEQV TKEATEALRE ETEKLNINKD
Length:200
Mass (Da):22,356
Last modified:November 1, 1995 - v1
Checksum:i8089CFC062E65395
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti118A → P no nucleotide entry (PubMed:3136928).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U34385 Genomic DNA Translation: AAB60315.1
Z67751 Genomic DNA Translation: CAA91605.1
Z73595 Genomic DNA Translation: CAA97960.1
AY558138 Genomic DNA Translation: AAS56464.1
M21813 Genomic DNA No translation available.
BK006949 Genomic DNA Translation: DAA11198.1
PIRiS61025
RefSeqiNP_015085.1, NM_001184053.1

Genome annotation databases

EnsemblFungiiYPL239W; YPL239W; YPL239W
GeneIDi855837
KEGGisce:YPL239W

Similar proteinsi

Entry informationi

Entry nameiYAR1_YEAST
AccessioniPrimary (citable) accession number: P46683
Secondary accession number(s): D6W3D2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 18, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

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