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Entry version 136 (23 Feb 2022)
Sequence version 2 (01 Oct 1996)
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Protein

Protein STB2

Gene

STB2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein STB2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:STB2
Ordered Locus Names:YMR053C
ORF Names:YM9796.06C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XIII

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000004657, STB2

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
FungiDB:YMR053C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000722521 – 850Protein STB2Add BLAST850

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei594PhosphoserineCombined sources1
Modified residuei625PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P46679

PRoteomics IDEntifications database

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PRIDEi
P46679

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P46679

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SIN3.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
35229, 116 interactors

Database of interacting proteins

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DIPi
DIP-1725N

Protein interaction database and analysis system

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IntActi
P46679, 4 interactors

Molecular INTeraction database

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MINTi
P46679

STRING: functional protein association networks

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STRINGi
4932.YMR053C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

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RNActi
P46679, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

To yeast STB6.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502QT8Q, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00940000176579

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_010065_0_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P46679

Identification of Orthologs from Complete Genome Data

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OMAi
YIVEQWI

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR038919, Stb2/Stb6

The PANTHER Classification System

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PANTHERi
PTHR31011, PTHR31011, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P46679-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVMADTIATG DKTSQFDGKH MQDLERIYST RDTLDDNFFG ERGQKDANGD
60 70 80 90 100
YYDELNNEET NYSGSSYYGH SDDSEVVGLI KNDTVSQLPP LDSFIFPDSR
110 120 130 140 150
ALFLLDLGNY ADLTYEEIIV HGFEIYIVEQ WVACRNLSTL ITSYTGNSQD
160 170 180 190 200
TISGVRVVLP KDTSMWPGRF RLYFEELMEF ARPKFTPKGT LFITNLSGVS
210 220 230 240 250
FGLNLLHVEC GDLRTIWKDF EVNFDLKNLH CGGRSANLLC PPTMASLDKF
260 270 280 290 300
SQLFKIPTNG FIAQYPQMIQ QQQPRLPEEE YKTVGNSKCR NTDSKSPVVE
310 320 330 340 350
MVTLIQISLS YFNLLSKNYQ TDGLLCEDTK RAIDEWWETY GKLYLGTEKP
360 370 380 390 400
RNECTLGPTT VAGLISLILC CYFKLMIENC ISSKDPFDEA GFFQGIYNFQ
410 420 430 440 450
KKHGLNKRKS RVYLDPRTLE KLFEVTAKVS SKDIFKLKKM VTSTVQDIIG
460 470 480 490 500
KGNPINLSHK ILTTDLDTLI HNIHGGSVGL LWKGKGHPRK CCTDISNEEF
510 520 530 540 550
LKFNYQRGDP DGQIREREML LEKFRLERIA YAQKHASKKV SSSSLDTSED
560 570 580 590 600
IGRTNAMPSS ATVSSMFPNY DNTKYAYNFG INKLYQGEYY RRNSFPYCKD
610 620 630 640 650
RTHDNIYEDL SELKEKSSRL YRCNSSSAVQ NIVEKWDLPF DPSVVRIARD
660 670 680 690 700
LLRMKYDIQA QQHIQEMDEH YMGKLNKEGT VGQYSKFNER YKRLQELYKK
710 720 730 740 750
YSDGAKVFEG RFEDIDNKQQ LLLHEMQELN SLSSRLKYDM RILEVRVRDI
760 770 780 790 800
ESSVAQFDSK LIGLKSSLQG QGKTGICSAI DPKSDKDEYD RCVNDLMTTN
810 820 830 840 850
NPTYEALCLK MLSRRYFKDL KNDTVGWFRW LFGNNSLHNN ASEDDRGIRV
Length:850
Mass (Da):97,828
Last modified:October 1, 1996 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDEB5AF3F442592E9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
U33438 Genomic DNA Translation: AAA75481.1
Z49703 Genomic DNA Translation: CAA89763.1
U35609 Genomic DNA Translation: AAB39036.1
BK006946 Genomic DNA Translation: DAA09952.1

Protein sequence database of the Protein Information Resource

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PIRi
S54553

NCBI Reference Sequences

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RefSeqi
NP_013769.1, NM_001182551.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YMR053C_mRNA; YMR053C; YMR053C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
855075

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YMR053C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33438 Genomic DNA Translation: AAA75481.1
Z49703 Genomic DNA Translation: CAA89763.1
U35609 Genomic DNA Translation: AAB39036.1
BK006946 Genomic DNA Translation: DAA09952.1
PIRiS54553
RefSeqiNP_013769.1, NM_001182551.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi35229, 116 interactors
DIPiDIP-1725N
IntActiP46679, 4 interactors
MINTiP46679
STRINGi4932.YMR053C

PTM databases

iPTMnetiP46679

Proteomic databases

PaxDbiP46679
PRIDEiP46679

Genome annotation databases

EnsemblFungiiYMR053C_mRNA; YMR053C; YMR053C
GeneIDi855075
KEGGisce:YMR053C

Organism-specific databases

SGDiS000004657, STB2
VEuPathDBiFungiDB:YMR053C

Phylogenomic databases

eggNOGiENOG502QT8Q, Eukaryota
GeneTreeiENSGT00940000176579
HOGENOMiCLU_010065_0_0_1
InParanoidiP46679
OMAiYIVEQWI

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P46679
RNActiP46679, protein

Family and domain databases

InterProiView protein in InterPro
IPR038919, Stb2/Stb6
PANTHERiPTHR31011, PTHR31011, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTB2_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46679
Secondary accession number(s): D6VZM8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: February 23, 2022
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names
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