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Protein

Transcription factor TFIIIB component B''

Gene

BDP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

General activator of RNA polymerase III transcription.

GO - Molecular functioni

GO - Biological processi

  • DNA-templated transcriptional open complex formation Source: SGD
  • positive regulation of transposon integration Source: SGD
  • regulation of transcription, DNA-templated Source: MGI
  • RNA polymerase III transcriptional preinitiation complex assembly Source: SGD

Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-33075-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor TFIIIB component B''
Alternative name(s):
TFIIIB90
Gene namesi
Name:BDP1
Synonyms:TFC5
Ordered Locus Names:YNL039W
ORF Names:N2682
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL039W
SGDiS000004984 BDP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000724981 – 594Transcription factor TFIIIB component B''Add BLAST594

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei49PhosphoserineCombined sources1
Modified residuei178PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP46678
PaxDbiP46678
PRIDEiP46678

PTM databases

iPTMnetiP46678

Interactioni

Subunit structurei

TFIIIB comprises the TATA-binding protein (TBP), the B-related factor (BRF) and the B" component (BDP1). Interacts with TFC4.2 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • TFIIIC-class transcription factor binding Source: SGD

Protein-protein interaction databases

BioGridi35785, 52 interactors
ComplexPortaliCPX-1143 Transcription factor TFIIIB complex
DIPiDIP-964N
IntActiP46678, 17 interactors
MINTiP46678
STRINGi4932.YNL039W

Structurei

3D structure databases

ProteinModelPortaliP46678
SMRiP46678
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini415 – 466SANTAdd BLAST52

Sequence similaritiesi

Belongs to the TFC5 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000012762
HOGENOMiHOG000066069
KOiK15198
OMAiNEERKHP
OrthoDBiEOG092C5UXM

Family and domain databases

CDDicd00167 SANT, 1 hit
InterProiView protein in InterPro
IPR017174 Bdp1_fungi
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR030701 TFIIIB_B''
PANTHERiPTHR22929 PTHR22929, 1 hit
PIRSFiPIRSF037327 TFIIIB_Bdp1_fun, 1 hit
SMARTiView protein in SMART
SM00717 SANT, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit

Sequencei

Sequence statusi: Complete.

P46678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSIVNKSGT RFAPKVRQRR AATGGTPTPK PRTPQLFIPE SKEIEEDNSD
60 70 80 90 100
NDKGVDENET AIVEKPSLVG ERSLEGFTLT GTNGHDNEIG DEGPIDASTQ
110 120 130 140 150
NPKADVIEDN VTLKPAPLQT HRDQKVPRSS RLASLSKDNE SRPSFKPSFL
160 170 180 190 200
DSSSNSNGTA RRLSTISNKL PKKIRLGSIT ENDMNLKTFK RHRVLGKPSS
210 220 230 240 250
AKKPAGAHRI SIVSKISPPT AMTDSLDRNE FSSETSTSRE ADENENYVIS
260 270 280 290 300
KVKDIPKKVR DGESAKYFID EENFTMAELC KPNFPIGQIS ENFEKSKMAK
310 320 330 340 350
KAKLEKRRHL RELRMRARQE FKPLHSLTKE EQEEEEEKRK EERDKLLNAD
360 370 380 390 400
IPESDRKAHT AIQLKLNPDG TMAIDEETMV VDRHKNASIE NEYKEKVDEN
410 420 430 440 450
PFANLYNYGS YGRGSYTDPW TVEEMIKFYK ALSMWGTDFN LISQLYPYRS
460 470 480 490 500
RKQVKAKFVN EEKKRPILIE LALRSKLPPN FDEYCCEIKK NIGTVADFNE
510 520 530 540 550
KLIELQNEHK HHMKEIEEAK NTAKEEDQTA QRLNDANLNK KGSGGIMTND
560 570 580 590
LKVYRKTEVV LGTIDDLKRK KLKERNNDDN EDNEGSEEEP EIDQ
Length:594
Mass (Da):67,688
Last modified:November 1, 1995 - v1
Checksum:i7B0115BBB2491175
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31819 Genomic DNA Translation: AAC49073.1
U38415 Genomic DNA Translation: AAC49364.1
U37533 Genomic DNA Translation: AAC49348.1
Z71315 Genomic DNA Translation: CAA95906.1
BK006947 Genomic DNA Translation: DAA10506.1
PIRiS62141
RefSeqiNP_014359.3, NM_001182878.3

Genome annotation databases

EnsemblFungiiYNL039W; YNL039W; YNL039W
GeneIDi855689
KEGGisce:YNL039W

Similar proteinsi

Entry informationi

Entry nameiTFC5_YEAST
AccessioniPrimary (citable) accession number: P46678
Secondary accession number(s): D6W1E0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 18, 2018
This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

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