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Protein

B1 bradykinin receptor

Gene

BDKRB1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • bradykinin receptor activity Source: ProtInc
  • peptide binding Source: Ensembl

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-418594 G alpha (i) signalling events

SIGNOR Signaling Network Open Resource

More...
SIGNORi
P46663

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
B1 bradykinin receptor
Short name:
B1R
Short name:
BK-1 receptor
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BDKRB1
Synonyms:BRADYB1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000100739.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1029 BDKRB1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
600337 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P46663

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 40ExtracellularSequence analysisAdd BLAST40
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei41 – 64Helical; Name=1Sequence analysisAdd BLAST24
Topological domaini65 – 73CytoplasmicSequence analysis9
Transmembranei74 – 98Helical; Name=2Sequence analysisAdd BLAST25
Topological domaini99 – 111ExtracellularSequence analysisAdd BLAST13
Transmembranei112 – 133Helical; Name=3Sequence analysisAdd BLAST22
Topological domaini134 – 155CytoplasmicSequence analysisAdd BLAST22
Transmembranei156 – 178Helical; Name=4Sequence analysisAdd BLAST23
Topological domaini179 – 199ExtracellularSequence analysisAdd BLAST21
Transmembranei200 – 226Helical; Name=5Sequence analysisAdd BLAST27
Topological domaini227 – 247CytoplasmicSequence analysisAdd BLAST21
Transmembranei248 – 272Helical; Name=6Sequence analysisAdd BLAST25
Topological domaini273 – 291ExtracellularSequence analysisAdd BLAST19
Transmembranei292 – 314Helical; Name=7Sequence analysisAdd BLAST23
Topological domaini315 – 353CytoplasmicSequence analysisAdd BLAST39

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
623

Open Targets

More...
OpenTargetsi
ENSG00000100739

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA79

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL4308

IUPHAR/BPS Guide to PHARMACOLOGY

More...
GuidetoPHARMACOLOGYi
41

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BDKRB1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
85681914

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000691811 – 353B1 bradykinin receptorAdd BLAST353

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi14N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi22N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi110 ↔ 189PROSITE-ProRule annotation
Glycosylationi185N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi330S-palmitoyl cysteineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P46663

PeptideAtlas

More...
PeptideAtlasi
P46663

PRoteomics IDEntifications database

More...
PRIDEi
P46663

ProteomicsDB human proteome resource

More...
ProteomicsDBi
55746

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P46663

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P46663

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000100739 Expressed in 74 organ(s), highest expression level in omental fat pad

CleanEx database of gene expression profiles

More...
CleanExi
HS_BDKRB1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P46663 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P46663 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA002935

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
KNG1P010422EBI-6623218,EBI-6623250

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
P46663, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000216629

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
P46663

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P46663

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3656 Eukaryota
ENOG410XRW9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153275

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000010314

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG103183

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P46663

KEGG Orthology (KO)

More...
KOi
K03915

Identification of Orthologs from Complete Genome Data

More...
OMAi
WTPYHFF

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0D52

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P46663

TreeFam database of animal gene trees

More...
TreeFami
TF330024

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001186 Brdyknn_1_rcpt
IPR000496 Brdyknn_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00001 7tm_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00425 BRADYKININR
PR00993 BRADYKINNB1R
PR00237 GPCRRHODOPSN

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P46663-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSWPPLEL QSSNQSQLFP QNATACDNAP EAWDLLHRVL PTFIISICFF
60 70 80 90 100
GLLGNLFVLL VFLLPRRQLN VAEIYLANLA ASDLVFVLGL PFWAENIWNQ
110 120 130 140 150
FNWPFGALLC RVINGVIKAN LFISIFLVVA ISQDRYRVLV HPMASRRQQR
160 170 180 190 200
RRQARVTCVL IWVVGGLLSI PTFLLRSIQA VPDLNITACI LLLPHEAWHF
210 220 230 240 250
ARIVELNILG FLLPLAAIVF FNYHILASLR TREEVSRTRC GGRKDSKTTA
260 270 280 290 300
LILTLVVAFL VCWAPYHFFA FLEFLFQVQA VRGCFWEDFI DLGLQLANFF
310 320 330 340 350
AFTNSSLNPV IYVFVGRLFR TKVWELYKQC TPKSLAPISS SHRKEIFQLF

WRN
Length:353
Mass (Da):40,495
Last modified:January 10, 2006 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB62B0690A7593077
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V4Y2G3V4Y2_HUMAN
B1 bradykinin receptor
BDKRB1
284Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti146R → G (PubMed:8063797).Curated1
Sequence conflicti146R → G (PubMed:8651911).Curated1
Sequence conflicti146R → G (PubMed:8660997).Curated1
Sequence conflicti240 – 243CGGR → VRGP (PubMed:8063797).Curated4
Sequence conflicti240 – 243CGGR → VRGP (PubMed:8651911).Curated4
Sequence conflicti240 – 243CGGR → VRGP (PubMed:8660997).Curated4
Sequence conflicti246S → R (PubMed:8651911).Curated1
Sequence conflicti259F → S in AAC50594 (PubMed:8651911).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_014359250A → V. Corresponds to variant dbSNP:rs2229459Ensembl.1
Natural variantiVAR_049376317R → Q. Corresponds to variant dbSNP:rs8004609Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U12512 mRNA Translation: AAA21346.1
U22346 Genomic DNA Translation: AAC50594.1
U48231 Genomic DNA Translation: AAB60693.1
AJ238044 mRNA Translation: CAB45650.1
AB065896 Genomic DNA Translation: BAC06112.1
AY275464 Genomic DNA Translation: AAP32296.1
AK291970 mRNA Translation: BAF84659.1
CH471061 Genomic DNA Translation: EAW81632.1
BC034705 mRNA Translation: AAH34705.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9943.1

Protein sequence database of the Protein Information Resource

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PIRi
A53858

NCBI Reference Sequences

More...
RefSeqi
NP_000701.2, NM_000710.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.525572

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000216629; ENSP00000216629; ENSG00000100739
ENST00000611804; ENSP00000479276; ENSG00000100739

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
623

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:623

UCSC genome browser

More...
UCSCi
uc001yfh.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Wikipedia

Bradykinin receptor entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12512 mRNA Translation: AAA21346.1
U22346 Genomic DNA Translation: AAC50594.1
U48231 Genomic DNA Translation: AAB60693.1
AJ238044 mRNA Translation: CAB45650.1
AB065896 Genomic DNA Translation: BAC06112.1
AY275464 Genomic DNA Translation: AAP32296.1
AK291970 mRNA Translation: BAF84659.1
CH471061 Genomic DNA Translation: EAW81632.1
BC034705 mRNA Translation: AAH34705.1
CCDSiCCDS9943.1
PIRiA53858
RefSeqiNP_000701.2, NM_000710.3
UniGeneiHs.525572

3D structure databases

ProteinModelPortaliP46663
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP46663, 1 interactor
STRINGi9606.ENSP00000216629

Chemistry databases

BindingDBiP46663
ChEMBLiCHEMBL4308
GuidetoPHARMACOLOGYi41

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiP46663
PhosphoSitePlusiP46663

Polymorphism and mutation databases

BioMutaiBDKRB1
DMDMi85681914

Proteomic databases

PaxDbiP46663
PeptideAtlasiP46663
PRIDEiP46663
ProteomicsDBi55746

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
623
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000216629; ENSP00000216629; ENSG00000100739
ENST00000611804; ENSP00000479276; ENSG00000100739
GeneIDi623
KEGGihsa:623
UCSCiuc001yfh.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
623
DisGeNETi623
EuPathDBiHostDB:ENSG00000100739.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BDKRB1
HGNCiHGNC:1029 BDKRB1
HPAiHPA002935
MIMi600337 gene
neXtProtiNX_P46663
OpenTargetsiENSG00000100739
PharmGKBiPA79

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00940000153275
HOGENOMiHOG000010314
HOVERGENiHBG103183
InParanoidiP46663
KOiK03915
OMAiWTPYHFF
OrthoDBiEOG091G0D52
PhylomeDBiP46663
TreeFamiTF330024

Enzyme and pathway databases

ReactomeiR-HSA-375276 Peptide ligand-binding receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-418594 G alpha (i) signalling events
SIGNORiP46663

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Bradykinin_receptor_B1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
623

Protein Ontology

More...
PROi
PR:P46663

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000100739 Expressed in 74 organ(s), highest expression level in omental fat pad
CleanExiHS_BDKRB1
ExpressionAtlasiP46663 baseline and differential
GenevisibleiP46663 HS

Family and domain databases

InterProiView protein in InterPro
IPR001186 Brdyknn_1_rcpt
IPR000496 Brdyknn_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00425 BRADYKININR
PR00993 BRADYKINNB1R
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBKRB1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46663
Secondary accession number(s): A8K7F5, Q546S7, Q8N0Y8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 10, 2006
Last modified: December 5, 2018
This is version 169 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  3. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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