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UniProtKB - P46576 (SAM50_CAEEL)

Entry version 123 (25 May 2022)
Sequence version 2 (16 Jan 2004)
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Protein

SAM50-like protein gop-3

Gene

gop-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the maintenance of the structure of mitochondrial cristae.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Protein family/group databases

Transport Classification Database

More...TCDBi		1.B.33.3.7, the outer membrane protein insertion porin (bam complex) (ompip) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SAM50-like protein gop-3
Alternative name(s):
Gro-1 operon protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gop-3
ORF Names:C34E10.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...WormBasei		C34E10.1 ; CE26880 ; WBGene00001662 ; gop-3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002159401 – 434SAM50-like protein gop-3Add BLAST434

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P46576

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P46576

PeptideAtlas

More...PeptideAtlasi		P46576

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		WBGene00001662, Expressed in material anatomical entity and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with the mitochondrial contact site and cristae organizing system (MICOS) complex (also known as MINOS or MitOS complex).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		40954, 6 interactors

STRING: functional protein association networks

More...STRINGi		6239.C34E10.1.2

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P46576

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P46576

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Its C-terminal part seems to contain many membrane-spanning sided beta-sheets, that have the potential to adopt a transmembrane beta-barrel type structure.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAM50/omp85 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2602, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011355

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014798_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P46576

Identification of Orthologs from Complete Genome Data

More...OMAi		REHCGPK

Database of Orthologous Groups

More...OrthoDBi		844748at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P46576

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000184, Bac_surfAg_D15
IPR039910, D15-like

The PANTHER Classification System

More...PANTHERi		PTHR12815, PTHR12815, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01103, Omp85, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P46576-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEKTFHKAQ TIRAKASGVP SIVEAVQFHG VRITKNDALV KEVSELYRSK 
        60         70         80         90        100
NLDELVHNSH LAARHLQEVG LMDNAVALID TSPSSNEGYV VNFLVREPKS 
       110        120        130        140        150
FTAGVKAGVS TNGDADVSLN AGKQSVGGRG EAINTQYTYT VKGDHCFNIS 
       160        170        180        190        200
AIKPFLGWQK YSNVSATLYR SLAHMPWNQS DVDENAAVLA YNGQLWNQKL 
       210        220        230        240        250
LHQVKLNAIW RTLRATRDAA FSVREQAGHT LKFSLENAVA VDTRDRPILA 
       260        270        280        290        300
SRGILARFAQ EYAGVFGDAS FVKNTLDLQA AAPLPLGFIL AASFQAKHLK 
       310        320        330        340        350
GLGDREVHIL DRCYLGGQQD VRGFGLNTIG VKADNSCLGG GASLAGVVHL 
       360        370        380        390        400
YRPLIPPNML FAHAFLASGS VASVHSKNLV QQLQDTQRVS AGFGLAFVFK 
       410        420        430 
SIFRLELNYT YPLKYVLGDS LLGGFHIGAG VNFL
Length:434
Mass (Da):47,127
Last modified:January 16, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3FC34B28F04079C4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY052771 mRNA Translation: AAL14110.1
FO080774 Genomic DNA Translation: CCD66645.1

Protein sequence database of the Protein Information Resource

More...PIRi		T15758

NCBI Reference Sequences

More...RefSeqi		NP_498119.1, NM_065718.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		C34E10.1.1; C34E10.1.1; WBGene00001662
C34E10.1.2; C34E10.1.2; WBGene00001662

Database of genes from NCBI RefSeq genomes

More...GeneIDi		175723

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cel:CELE_C34E10.1

UCSC genome browser

More...UCSCi		C34E10.1.2, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY052771 mRNA Translation: AAL14110.1
FO080774 Genomic DNA Translation: CCD66645.1
PIRiT15758
RefSeqiNP_498119.1, NM_065718.5

3D structure databases

AlphaFoldDBiP46576
SMRiP46576
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi40954, 6 interactors
STRINGi6239.C34E10.1.2

Protein family/group databases

TCDBi1.B.33.3.7, the outer membrane protein insertion porin (bam complex) (ompip) family

Proteomic databases

EPDiP46576
PaxDbiP46576
PeptideAtlasiP46576

Genome annotation databases

EnsemblMetazoaiC34E10.1.1; C34E10.1.1; WBGene00001662
C34E10.1.2; C34E10.1.2; WBGene00001662
GeneIDi175723
KEGGicel:CELE_C34E10.1
UCSCiC34E10.1.2, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		175723
WormBaseiC34E10.1 ; CE26880 ; WBGene00001662 ; gop-3

Phylogenomic databases

eggNOGiKOG2602, Eukaryota
GeneTreeiENSGT00390000011355
HOGENOMiCLU_014798_0_0_1
InParanoidiP46576
OMAiREHCGPK
OrthoDBi844748at2759
PhylomeDBiP46576

Miscellaneous databases

Protein Ontology

More...PROi		PR:P46576

Gene expression databases

BgeeiWBGene00001662, Expressed in material anatomical entity and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR000184, Bac_surfAg_D15
IPR039910, D15-like
PANTHERiPTHR12815, PTHR12815, 1 hit
PfamiView protein in Pfam
PF01103, Omp85, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSAM50_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46576
Secondary accession number(s): Q95UF7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 16, 2004
Last modified: May 25, 2022
This is version 123 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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