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UniProtKB - P46474 (YHDP_ECOLI)

Entry version 133 (10 Feb 2021)
Sequence version 4 (23 Nov 2004)
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Protein

Uncharacterized protein YhdP

Gene

yhdP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G7690-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YhdP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yhdP
Synonyms:yhdQ, yhdR
Ordered Locus Names:b4472, JW5542
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001392330 – 1266Uncharacterized protein YhdPAdd BLAST1237

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P46474

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P46474

PRoteomics IDEntifications database

More...PRIDEi		P46474

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261747, 6 interactors

Database of interacting proteins

More...DIPi		DIP-12299N

Protein interaction database and analysis system

More...IntActi		P46474, 2 interactors

STRING: functional protein association networks

More...STRINGi		511145.b4472

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG3164, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_003522_0_0_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P46474

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR032712, AsmA_C
IPR011836, CHP02099
IPR025263, DUF3971

The PANTHER Classification System

More...PANTHERi		PTHR38690, PTHR38690, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13502, AsmA_2, 1 hit
PF13116, DUF3971, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR02099, TIGR02099, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P46474-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRLPGILLL TGAALVVIAA LLVSGLRIAL PHLDAWRPEI LNKIESATGM 
        60         70         80         90        100
PVEASQLSAS WQNFGPTLEA HDIRAELKDG GEFSVKRVTL ALDVWQSLLH 
       110        120        130        140        150
MRWQFRDLTF WQLRFRTNTP ITSGGSDDSL EASHISDLFL RQFDHFDLRD 
       160        170        180        190        200
SEVSFLTPSG QRAELAIPQL TWLNDPRRHR AEGLVSLSSL TGQHGVMQVR 
       210        220        230        240        250
MDLRDDEGLL SNGRVWLQAD DIDLKPWLGK WMQDNIALET AQFSLEGWMT 
       260        270        280        290        300
IDKGDVTGGD VWLKQGGASW LGEKQTHTLS VDNLTAHITR ENPGWQFSIP 
       310        320        330        340        350
DTRITMDGKP WPSGALTLAW IPEQDVGGKD NKRSDELRIR ASNLELAGLE 
       360        370        380        390        400
GIRPLAAKLS PALGDVWRST QPSGKINTLA LDIPLQAADK TRFQASWSDL 
       410        420        430        440        450
AWKQWKLLPG AEHFSGTLSG SVENGLLTAS MKQAKMPYET VFRAPLEIAD 
       460        470        480        490        500
GQATISWLNN NKGFQLDGRN IDVKAKAVHA RGGFRYLQPA NDEPWLGILA 
       510        520        530        540        550
GISTDDGSQA WRYFPENLMG KDLVDYLSGA IQGGEADNAT LVYGGNPQLF 
       560        570        580        590        600
PYKHNEGQFE VLVPLRNAKF AFQPDWPALT NLDIELDFIN DGLWMKTDGV 
       610        620        630        640        650
NLGGVRASNL TAVIPDYSKE KLLIDADIKG PGKAVGPYFD ETPLKDSLGA 
       660        670        680        690        700
TLQELQLDGD VNARLHLDIP LNGELVTAKG EVTLRNNSLF IKPLDSTLKN 
       710        720        730        740        750
LSGKFSFINS DLQSEPLTAS WFNQPLNVDF STKEGAKAYQ VAVNLNGNWQ 
       760        770        780        790        800
PAKTGVLPEA VNEALSGSVA WDGKVGIDLP YHAGATYNIE LNGDLKNVSS 
       810        820        830        840        850
HLPSPLAKPA GEPLAVNVKV DGNLNSFELT GQAGADNHFN SRWLLGQKLT 
       860        870        880        890        900
LDRAIWAADS KTLPPLPEQS GVELNMPPMN GAEWLALFQK GAAESVGGAA 
       910        920        930        940        950
SFPQHITLRT PMLSLGNQQW NNLSIVSQPT ANGTLVEAQG REINATLAMR 
       960        970        980        990       1000
NNAPWLANIK YLYYNPSVAK TRGDSTPSSP FPTTERINFR GWPDAQIRCT 
      1010       1020       1030       1040       1050
ECWFWGQKFG RIDSDITISG DTLTLTNGLI DTGFSRLTAD GEWVNNPGNE 
      1060       1070       1080       1090       1100
RTSLKGKLRG QKIDAAAEFF GVTTPIRQSS FNVDYDLHWR KAPWQPDEAT 
      1110       1120       1130       1140       1150
LNGIIHTQLG KGEITEINTG HAGQLLRLLS VDALMRKLRF DFRDTFGEGF 
      1160       1170       1180       1190       1200
YFDSIRSTAW IKDGVMHTDD TLVDGLEADI AMKGSVNLVR RDLNMEAVVA 
      1210       1220       1230       1240       1250
PEISATVGVA AAFAVNPIVG AAVFAASKVL GPLWSKVSIL RYHISGPLDD 
      1260 
PQINEVLRQP RKEKAQ
Length:1,266
Mass (Da):139,053
Last modified:November 23, 2004 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i414AB7D36E5A90DE
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA58047 differs from that shown. Reason: Frameshift. Produces three separate ORFs (yhdP, yhdQ and yhdR).Curated
The sequence AAA58048 differs from that shown. Reason: Frameshift. Produces three separate ORFs (yhdP, yhdQ and yhdR).Curated
The sequence AAA58049 differs from that shown. Reason: Frameshift. Produces three separate ORFs (yhdP, yhdQ and yhdR).Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti351G → A in AAA58048 (PubMed:9278503).Curated1
Sequence conflicti354P → R in AAA58048 (PubMed:9278503).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58047.1 Frameshift.
U18997 Genomic DNA Translation: AAA58048.1 Frameshift.
U18997 Genomic DNA Translation: AAA58049.1 Frameshift.
U00096 Genomic DNA Translation: AAT48173.1
AP009048 Genomic DNA Translation: BAE77288.1
X57166 Genomic DNA No translation available.

Protein sequence database of the Protein Information Resource

More...PIRi		G65116
H65116

NCBI Reference Sequences

More...RefSeqi		WP_001253618.1, NZ_SSZK01000034.1
YP_026208.1, NC_000913.3

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAT48173; AAT48173; b4472
BAE77288; BAE77288; BAE77288

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2847740
57728484

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW5542
eco:b4472

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.3483

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58047.1 Frameshift.
U18997 Genomic DNA Translation: AAA58048.1 Frameshift.
U18997 Genomic DNA Translation: AAA58049.1 Frameshift.
U00096 Genomic DNA Translation: AAT48173.1
AP009048 Genomic DNA Translation: BAE77288.1
X57166 Genomic DNA No translation available.
PIRiG65116
H65116
RefSeqiWP_001253618.1, NZ_SSZK01000034.1
YP_026208.1, NC_000913.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4261747, 6 interactors
DIPiDIP-12299N
IntActiP46474, 2 interactors
STRINGi511145.b4472

Proteomic databases

jPOSTiP46474
PaxDbiP46474
PRIDEiP46474

Genome annotation databases

EnsemblBacteriaiAAT48173; AAT48173; b4472
BAE77288; BAE77288; BAE77288
GeneIDi2847740
57728484
KEGGiecj:JW5542
eco:b4472
PATRICifig|1411691.4.peg.3483

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB2678

Phylogenomic databases

eggNOGiCOG3164, Bacteria
HOGENOMiCLU_003522_0_0_6
InParanoidiP46474

Enzyme and pathway databases

BioCyciEcoCyc:G7690-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P46474

Family and domain databases

InterProiView protein in InterPro
IPR032712, AsmA_C
IPR011836, CHP02099
IPR025263, DUF3971
PANTHERiPTHR38690, PTHR38690, 1 hit
PfamiView protein in Pfam
PF13502, AsmA_2, 1 hit
PF13116, DUF3971, 1 hit
TIGRFAMsiTIGR02099, TIGR02099, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYHDP_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46474
Secondary accession number(s): P46475
, P46476, P76676, Q2M8W8, Q6BF41
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 23, 2004
Last modified: February 10, 2021
This is version 133 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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