UniProtKB - P46468 (CDAT_PLAF7)
Protein
Putative cell division cycle ATPase
Gene
PF07_0047
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 568 – 575 | ATPSequence analysis | 8 | |
Nucleotide bindingi | 975 – 982 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATPase activity Source: GeneDB
- ATP binding Source: UniProtKB-KW
- polyubiquitin modification-dependent protein binding Source: GO_Central
- ubiquitin binding Source: GeneDB
GO - Biological processi
- autophagosome maturation Source: GO_Central
- ER-associated misfolded protein catabolic process Source: GO_Central
- macroautophagy Source: GO_Central
- mitotic spindle disassembly Source: GO_Central
- regulation of cell cycle process Source: GeneDB
- retrograde protein transport, ER to cytosol Source: GO_Central
- ubiquitin-dependent ERAD pathway Source: GeneDB
Keywordsi
Biological process | Cell cycle |
Ligand | ATP-binding, Nucleotide-binding |
Protein family/group databases
TCDBi | 3.A.25.2.1, the symbiont-specific erad-like machinery (selma) family |
Names & Taxonomyi
Protein namesi | Recommended name: Putative cell division cycle ATPase |
Gene namesi | ORF Names:PF07_0047 |
Organismi | Plasmodium falciparum (isolate 3D7) |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0711000 |
Subcellular locationi
GO - Cellular componenti
- apicoplast Source: GeneDB
- cytoplasm Source: GO_Central
- cytosol Source: GO_Central
- nucleus Source: GO_Central
- VCP-NPL4-UFD1 AAA ATPase complex Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000084593 | 1 – 1229 | Putative cell division cycle ATPaseAdd BLAST | 1229 |
Proteomic databases
PRIDEi | P46468 |
PTM databases
SwissPalmi | P46468 |
Interactioni
GO - Molecular functioni
- polyubiquitin modification-dependent protein binding Source: GO_Central
- ubiquitin binding Source: GeneDB
Protein-protein interaction databases
BioGRIDi | 1209952, 1 interactor |
IntActi | P46468, 1 interactor |
Family & Domainsi
Sequence similaritiesi
Belongs to the AAA ATPase family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
HOGENOMi | CLU_000688_12_3_1 |
InParanoidi | P46468 |
OMAi | RCSIFKA |
PhylomeDBi | P46468 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR009010, Asp_de-COase-like_dom_sf IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR029067, CDC48_domain_2-like_sf IPR003338, CDC4_N-term_subdom IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 2 hits PF17862, AAA_lid_3, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits SM01073, CDC48_N, 1 hit |
SUPFAMi | SSF50692, SSF50692, 1 hit SSF52540, SSF52540, 2 hits SSF54585, SSF54585, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 2 hits |
i Sequence
Sequence statusi: Complete.
P46468-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKVRKMHYPL FSFTEYLSCY IILYFFVFLP NYSYAININN YHNKNNLWNI
60 70 80 90 100
NNKWNNQQSN HFSNNRIGHF LWGSKIRKNP LASISTSITT KKLENQKKKT
110 120 130 140 150
NKNESYSNVN DKYEHNNNTA HFVQINYKND QSNDTLSTYK NNNEMTVEGK
160 170 180 190 200
PNNLASGEGK KEIHNTTQKI LEKVDYFKER EKITNSYNNN NNNNKVIVTH
210 220 230 240 250
DNKNHTNYIN KVENKQSDDK IKNLNNKYIK KFKSHILQND ILGTISTMFW
260 270 280 290 300
SGKKNNNGNV KKGIKNVPMD EKSYSPNDHD NNSNNSNNNN NNDNNNSNNN
310 320 330 340 350
NNNNNGGKNN SYYNEKTQKG VNDKETNFLL KALDSGKFPT YCLVENIDEN
360 370 380 390 400
LDNFDIYMSK EKMDELNIND GATVLLKGKK KREMLGIARL DRSLKKHYVV
410 420 430 440 450
ISFAMKKNLR LMHNDIIKIH PFMNAKRIRN VVLSPFSDTI PNLSREELEK
460 470 480 490 500
AVIHPYLKNS YKPLRVNSNI YIYYKNNKIE FKVLKIISEE SENEEFGCIG
510 520 530 540 550
EHSQLTLAEE YLKREDYEEN NDDITYEDLG GMKKQLNKIR ELIELPLKYP
560 570 580 590 600
EIFMSIGISA PKGVLMHGIP GTGKTSIAKA IANESNAYCY IINGPEIMSK
610 620 630 640 650
HIGESEQKLR KIFKKASEKT PCIIFIDEID SIANKRSKSN NELEKRVVSQ
660 670 680 690 700
LLTLMDGLKK NNNVLVLAAT NRPNSIDPAL RRFGRFDREI EIPVPDEQGR
710 720 730 740 750
YEILLTKTKK MKLDPDVNLR KIAKECHGYV GADLAQLCFE AAIQCIKEHI
760 770 780 790 800
HFLDLDEEDF IEFMKISVDE DKKNMGNEPY GSSHTNNSNY INHLTESSNK
810 820 830 840 850
LSYTNMFPLN RKNTLLQNDK NEMNKDSSYD KKTDALDNYK NDSTIDMEKK
860 870 880 890 900
KNKKKSNFFF SNDDEETKNK NKTNVNQKKK KNPNDKLDKN ERRIPAYILN
910 920 930 940 950
KLTIKAKHFQ HALNICNPSS LRERQVQIPT VTWNDIGGMN EVKEQLKETI
960 970 980 990 1000
LYPLEYKHLY NKFNSNYNKG ILLYGPPGCG KTLLAKAIAN ECKANFISVK
1010 1020 1030 1040 1050
GPELLTMWFG ESEANVRDLF DKARAASPCI IFFDEIDSLA KERNSNTNND
1060 1070 1080 1090 1100
ASDRVINQIL TEIDGINEKK TIFIIAATNR PDILDKALTR PGRLDKLIYI
1110 1120 1130 1140 1150
SLPDLKSRYS IFKAILKNTP LNEDVDIHDM AKRTEGFSGA DITNLCQSAV
1160 1170 1180 1190 1200
NEAIKETIHL LNIRKKEQEE QRKKNKNSFK IDDTDTYDPV PTLSKKHFDL
1210 1220
AFKNARISIQ PEDVLKYEKF KEKLSLQDF
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 834 | D → N in AAA29520 (Ref. 3) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844506 Genomic DNA Translation: CAD50861.1 M96757 Genomic DNA Translation: AAA29520.1 |
RefSeqi | XP_001349023.1, XM_001348987.1 |
Genome annotation databases
EnsemblProtistsi | CAD50861; CAD50861; PF3D7_0711000 |
GeneDBi | PF3D7_0711000.1:pep |
GeneIDi | 2655095 |
KEGGi | pfa:PF3D7_0711000 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844506 Genomic DNA Translation: CAD50861.1 M96757 Genomic DNA Translation: AAA29520.1 |
RefSeqi | XP_001349023.1, XM_001348987.1 |
3D structure databases
SMRi | P46468 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 1209952, 1 interactor |
IntActi | P46468, 1 interactor |
Protein family/group databases
TCDBi | 3.A.25.2.1, the symbiont-specific erad-like machinery (selma) family |
PTM databases
SwissPalmi | P46468 |
Proteomic databases
PRIDEi | P46468 |
Genome annotation databases
EnsemblProtistsi | CAD50861; CAD50861; PF3D7_0711000 |
GeneDBi | PF3D7_0711000.1:pep |
GeneIDi | 2655095 |
KEGGi | pfa:PF3D7_0711000 |
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0711000 |
Phylogenomic databases
HOGENOMi | CLU_000688_12_3_1 |
InParanoidi | P46468 |
OMAi | RCSIFKA |
PhylomeDBi | P46468 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041569, AAA_lid_3 IPR009010, Asp_de-COase-like_dom_sf IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR029067, CDC48_domain_2-like_sf IPR003338, CDC4_N-term_subdom IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 2 hits PF17862, AAA_lid_3, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits SM01073, CDC48_N, 1 hit |
SUPFAMi | SSF50692, SSF50692, 1 hit SSF52540, SSF52540, 2 hits SSF54585, SSF54585, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CDAT_PLAF7 | |
Accessioni | P46468Primary (citable) accession number: P46468 Secondary accession number(s): Q8IBY0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | March 15, 2004 | |
Last modified: | December 2, 2020 | |
This is version 112 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families