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Entry version 134 (07 Apr 2021)
Sequence version 3 (16 Jun 2009)
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Protein

Putative competence-damage inducible protein

Gene

cinA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU16930-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative competence-damage inducible proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cinAUniRule annotation
Synonyms:ymfO, yzlB
Ordered Locus Names:BSU16930
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001567531 – 416Putative competence-damage inducible proteinAdd BLAST416

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P46323

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P46323

PRoteomics IDEntifications database

More...
PRIDEi
P46323

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU16930

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P46323

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CinA family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG1058, Bacteria
COG1546, Bacteria

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P46323

Identification of Orthologs from Complete Genome Data

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OMAi
PGVPYEM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P46323

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00885, cinA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.980.10, 1 hit
3.90.950.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00226_B, CinA_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036653, CinA-like_C
IPR008136, CinA_C
IPR041424, CinA_KH
IPR008135, Competence-induced_CinA
IPR036425, MoaB/Mog-like_dom_sf
IPR001453, MoaB/Mog_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02464, CinA, 1 hit
PF18146, CinA_KH, 1 hit
PF00994, MoCF_biosynth, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF006728, CinA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00852, MoCF_biosynth, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF142433, SSF142433, 1 hit
SSF53218, SSF53218, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00200, cinA_nterm, 1 hit
TIGR00177, molyb_syn, 1 hit
TIGR00199, PncC_domain, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P46323-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFPKKAEII AVGSELLLGQ IANTNAQFIS KQLAEIGVNV FYHTAVGDNP
60 70 80 90 100
ERLKQVIRIA EERSDFIIFS GGLGPTKDDL TKETIANTLG RPLVLNDEAF
110 120 130 140 150
QSIEDYFKRT KRTMSPNNRK QALVIEGSDV LANHFGMAPG MLTEHESRYY
160 170 180 190 200
MLLPGPPSEL RPMFENEAKP LLLKKMGSNE KIVSTVLRFF GIGESQLEAD
210 220 230 240 250
LEDIIDAQTN PTIAPLAADG EVTLRLTAKH ADEKETERLL KETEAVILER
260 270 280 290 300
VGEFFYGYDD TSLVKELSIA CKEKGITISA AESFTGGLFS EWLTDHSGAS
310 320 330 340 350
KLFAGGVVCY TNDVKQNVLG VKKETLDRFG AVSKECASEL AKGVQKLTGS
360 370 380 390 400
DIGISFTGVA GPDAQEGHEP GHVFIGISAN GKEEVHEFHF AGSRTGIRKR
410
GAKYGCHLIL KLLEQK
Length:416
Mass (Da):45,538
Last modified:June 16, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44E6366FE6CD0907
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti39N → H in AAB00568 (Ref. 1) Curated1
Sequence conflicti107F → P in AAB00568 (Ref. 1) Curated1
Sequence conflicti199A → P in AAB00568 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U56238 Genomic DNA Translation: AAB00568.1
U87792 Genomic DNA Translation: AAB47708.1
AL009126 Genomic DNA Translation: CAB13566.2
D50064 Genomic DNA Translation: BAA08782.1
X52132 Genomic DNA No translation available.

Protein sequence database of the Protein Information Resource

More...
PIRi
E69599

NCBI Reference Sequences

More...
RefSeqi
NP_389575.2, NC_000964.3
WP_003231847.1, NZ_JNCM01000035.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB13566; CAB13566; BSU_16930

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
939464

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU16930

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.1834

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56238 Genomic DNA Translation: AAB00568.1
U87792 Genomic DNA Translation: AAB47708.1
AL009126 Genomic DNA Translation: CAB13566.2
D50064 Genomic DNA Translation: BAA08782.1
X52132 Genomic DNA No translation available.
PIRiE69599
RefSeqiNP_389575.2, NC_000964.3
WP_003231847.1, NZ_JNCM01000035.1

3D structure databases

SMRiP46323
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU16930

Proteomic databases

jPOSTiP46323
PaxDbiP46323
PRIDEiP46323

Genome annotation databases

EnsemblBacteriaiCAB13566; CAB13566; BSU_16930
GeneIDi939464
KEGGibsu:BSU16930
PATRICifig|224308.179.peg.1834

Phylogenomic databases

eggNOGiCOG1058, Bacteria
COG1546, Bacteria
InParanoidiP46323
OMAiPGVPYEM
PhylomeDBiP46323

Enzyme and pathway databases

BioCyciBSUB:BSU16930-MONOMER

Family and domain databases

CDDicd00885, cinA, 1 hit
Gene3Di3.40.980.10, 1 hit
3.90.950.20, 1 hit
HAMAPiMF_00226_B, CinA_B, 1 hit
InterProiView protein in InterPro
IPR036653, CinA-like_C
IPR008136, CinA_C
IPR041424, CinA_KH
IPR008135, Competence-induced_CinA
IPR036425, MoaB/Mog-like_dom_sf
IPR001453, MoaB/Mog_dom
PfamiView protein in Pfam
PF02464, CinA, 1 hit
PF18146, CinA_KH, 1 hit
PF00994, MoCF_biosynth, 1 hit
PIRSFiPIRSF006728, CinA, 1 hit
SMARTiView protein in SMART
SM00852, MoCF_biosynth, 1 hit
SUPFAMiSSF142433, SSF142433, 1 hit
SSF53218, SSF53218, 1 hit
TIGRFAMsiTIGR00200, cinA_nterm, 1 hit
TIGR00177, molyb_syn, 1 hit
TIGR00199, PncC_domain, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCINA_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46323
Secondary accession number(s): P94511
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 16, 2009
Last modified: April 7, 2021
This is version 134 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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