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Protein

Uterine milk protein

Gene
N/A
Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei420 – 421Reactive bondBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor
Biological processPregnancy

Protein family/group databases

MEROPSiI04.981

Names & Taxonomyi

Protein namesi
Recommended name:
Uterine milk protein
Short name:
UTMP
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000003253126 – 459Uterine milk proteinAdd BLAST434

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi268N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP46201
PRIDEiP46201

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000009718

Structurei

3D structure databases

ProteinModelPortaliP46201
SMRiP46201
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family. UTMP subfamily.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000238521
HOVERGENiHBG098596
KOiK04525

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 2 hits
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P46201-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHGRMNLAL SLVFILCGLF NSIFCEKQQH SQKHMNLVLL KKISALSQKM
60 70 80 90 100
EAHPKDFAQE LFKALIIEDP RKNIIFSPMA MTTTLATLSL GIKSTMRTHH
110 120 130 140 150
PEDLKLEPKL LDVHKYLQPL VHVGRELVKQ KVLKHQHILF INRKMMVNQM
160 170 180 190 200
LLQQISKLQG MDIQMIDFTD IEKAKKTISH HVAEKTHTKI TNLITDLNPE
210 220 230 240 250
TILCLVNHIF FKGILKRAFQ PKLTQKEVFF VNDQTKVQVD MMRKTERMLY
260 270 280 290 300
SRSEELHATM VKMPCKGNVS LTLMLPDAGQ FDTDLKKMTA KRAKLQKISD
310 320 330 340 350
FRLVRLILPK LKISFKINFK HLLPKIDPKH ILTATAISQA ITSKAPLPNL
360 370 380 390 400
EALHQAEIEL SEHALTVDTA IHTDNLLKVP VKAKEVPAVV KVPMKAKEVP
410 420 430 440 450
AVVKVPMNTK EVPVVVKVPM NTKEVPVVVK VNRPFLLFVE DEKTQRDLFV

GKVLNPQVE
Length:459
Mass (Da):52,366
Last modified:November 1, 1995 - v1
Checksum:i4B2EAA6365418244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22095 mRNA Translation: AAB61677.1
RefSeqiNP_777222.1, NM_174797.3
UniGeneiBt.111575

Genome annotation databases

GeneIDi286871
KEGGibta:286871

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22095 mRNA Translation: AAB61677.1
RefSeqiNP_777222.1, NM_174797.3
UniGeneiBt.111575

3D structure databases

ProteinModelPortaliP46201
SMRiP46201
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000009718

Protein family/group databases

MEROPSiI04.981

Proteomic databases

PaxDbiP46201
PRIDEiP46201

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi286871
KEGGibta:286871

Organism-specific databases

CTDi612383

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000238521
HOVERGENiHBG098596
KOiK04525

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 2 hits
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUTMP_BOVIN
AccessioniPrimary (citable) accession number: P46201
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 25, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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