UniProtKB - P45769 (YHDZ_ECOLI)
Protein
Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ
Gene
yhdZ
Organism
Escherichia coli (strain K12)
Status
Functioni
Probably part of a binding-protein-dependent transport system YdhWXYZ for an amino acid. Probably responsible for energy coupling to the transport system.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 45 – 52 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATPase-coupled amino acid transmembrane transporter activity Source: InterPro
- ATP binding Source: EcoCyc
Keywordsi
Biological process | Amino-acid transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:YHDZ-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.3.26, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ |
Gene namesi | Name:yhdZ Ordered Locus Names:b3271, JW3239 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane Curated; Peripheral membrane protein Curated
GO - Cellular componenti
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093169 | 1 – 252 | Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZAdd BLAST | 252 |
Proteomic databases
PaxDbi | P45769 |
PRIDEi | P45769 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262453, 57 interactors |
ComplexPortali | CPX-4450, Putative amino acid ABC transporter complex |
IntActi | P45769, 4 interactors |
STRINGi | 511145.b3271 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 247 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 235 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Phylogenomic databases
eggNOGi | COG1126, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | P45769 |
PhylomeDBi | P45769 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR030679, ABC_ATPase_HisP-typ IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
PIRSFi | PIRSF039085, ABC_ATPase_HisP, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P45769-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSQILLQPAN AMITLENVNK WYGQFHVLKN INLTVQPGER IVLCGPSGSG
60 70 80 90 100
KSTTIRCINH LEEHQQGRIV VDGIELNEDI RNIERVRQEV GMVFQHFNLF
110 120 130 140 150
PHLTVLQNCT LAPIWVRKMP KKEAEDLAVH YLERVRIAEH AHKFPGQISG
160 170 180 190 200
GQQQRVAIAR SLCMKPKIML FDEPTSALDP EMVKEVLDTM IGLAQSGMTM
210 220 230 240 250
LCVTHEMGFA RTVADRVIFM DRGEIVEQAA PDEFFAHPKS ERTRAFLSQV
IH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA58075.1 U00096 Genomic DNA Translation: AAC76303.1 AP009048 Genomic DNA Translation: BAE77312.1 |
PIRi | A65120 |
RefSeqi | NP_417737.1, NC_000913.3 WP_000078349.1, NZ_SSZK01000072.1 |
Genome annotation databases
EnsemblBacteriai | AAC76303; AAC76303; b3271 BAE77312; BAE77312; BAE77312 |
GeneIDi | 947763 |
KEGGi | ecj:JW3239 eco:b3271 |
PATRICi | fig|1411691.4.peg.3456 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA58075.1 U00096 Genomic DNA Translation: AAC76303.1 AP009048 Genomic DNA Translation: BAE77312.1 |
PIRi | A65120 |
RefSeqi | NP_417737.1, NC_000913.3 WP_000078349.1, NZ_SSZK01000072.1 |
3D structure databases
SMRi | P45769 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262453, 57 interactors |
ComplexPortali | CPX-4450, Putative amino acid ABC transporter complex |
IntActi | P45769, 4 interactors |
STRINGi | 511145.b3271 |
Protein family/group databases
TCDBi | 3.A.1.3.26, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P45769 |
PRIDEi | P45769 |
Genome annotation databases
EnsemblBacteriai | AAC76303; AAC76303; b3271 BAE77312; BAE77312; BAE77312 |
GeneIDi | 947763 |
KEGGi | ecj:JW3239 eco:b3271 |
PATRICi | fig|1411691.4.peg.3456 |
Organism-specific databases
EchoBASEi | EB2686 |
Phylogenomic databases
eggNOGi | COG1126, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | P45769 |
PhylomeDBi | P45769 |
Enzyme and pathway databases
BioCyci | EcoCyc:YHDZ-MONOMER |
Miscellaneous databases
PROi | PR:P45769 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR030679, ABC_ATPase_HisP-typ IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
PIRSFi | PIRSF039085, ABC_ATPase_HisP, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YHDZ_ECOLI | |
Accessioni | P45769Primary (citable) accession number: P45769 Secondary accession number(s): Q2M8U4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families