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Entry version 163 (07 Apr 2021)
Sequence version 2 (01 Nov 1997)
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Protein

Probable autotransporter YfaL

Gene

yfaL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably an autotransporter.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG12850-MONOMER

Protein family/group databases

MEROPS protease database

More...
MEROPSi
U69.A11

Transport Classification Database

More...
TCDBi
1.B.12.1.5, the autotransporter-1 (at-1) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable autotransporter YfaL1 Publication
Cleaved into the following 2 chains:
Probable secreted autotransporter protein YfaL1 Publication
Probable autotransporter YfaL translocator1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yfaL
Synonyms:yfaF, yfaJ, yfaK
Ordered Locus Names:b2233, JW2227
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell outer membrane, Membrane, Periplasm, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the use of a specific protein in the biotechnological industry.<p><a href='/help/biotechnological_use' target='_top'>More...</a></p>Biotechnological usei

The 'passenger' domain (residues 29-785) can be replaced by other sequences which can be targeted to the cell surface (PubMed:22344647).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000271329 – 1250Probable autotransporter YfaLAdd BLAST1222
ChainiPRO_000044002729 – 696Probable secreted autotransporter protein YfaLAdd BLAST668
ChainiPRO_0000440028697 – 1250Probable autotransporter YfaL translocatorAdd BLAST554

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

An approximately 170 kDa protein is detected in the outer membrane, while a C-terminal 55 kDa fragment is detected in whole cells. The full-length putative autotransporter may be cleaved to release the mature protein from the outer membrane; Pefabloc SC, a Ser-Thr protease inhibitor prevents the appearance of the 55 kDa C--terminal fragment.1 Publication

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P45508

PRoteomics IDEntifications database

More...
PRIDEi
P45508

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4262133, 267 interactors

Protein interaction database and analysis system

More...
IntActi
P45508, 6 interactors

STRING: functional protein association networks

More...
STRINGi
511145.b2233

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P45508

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati919 – 92012
Repeati921 – 9222; approximate2
Repeati923 – 92432
Repeati925 – 9264; approximate2
Repeati927 – 92852
Repeati929 – 93062
Repeati931 – 93272
Repeati933 – 93482
Repeati935 – 93692
Repeati937 – 938102
Repeati939 – 940112
Repeati941 – 942122
Repeati943 – 944132
Repeati945 – 946142
Repeati947 – 948152
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini980 – 1250AutotransporterPROSITE-ProRule annotationAdd BLAST271

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni919 – 94815 X 2 AA approximate tandem repeats of [DTPE]-PAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi920 – 952Pro-richPROSITE-ProRule annotationAdd BLAST33

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space. Then, insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface, with subsequent cleavage. Finally, the mature protein remains tightly associated with the bacterium (Probable).Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG3468, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003013_0_0_6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P45508

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01344, PL2_Passenger_AT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.20, 1 hit
2.40.128.130, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043990, AC_1
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR013425, Autotrns_rpt
IPR006315, OM_autotransptr_brl
IPR012332, P22_tailspike-like_C_sf
IPR011050, Pectin_lyase_fold/virulence
IPR003368, POMP_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18883, AC_1, 1 hit
PF03797, Autotransporter, 1 hit
PF02415, Chlam_PMP, 3 hits
PF12951, PATR, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00869, Autotransporter, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103515, SSF103515, 1 hit
SSF51126, SSF51126, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01414, autotrans_barl, 1 hit
TIGR02601, autotrns_rpt, 1 hit
TIGR01376, POMP_repeat, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P45508-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRIIFLRKEY LSLLPSMIAS LFSANGVAAV TDSCQGYDVK ASCQASRQSL
60 70 80 90 100
SGITQDWSIA DGQWLVFSDM TNNASGGAVF LQQGAEFSLL PENETGMTLF
110 120 130 140 150
ANNTVTGEYN NGGAIFAKEN STLNLTDVIF SGNVAGGYGG AIYSSGTNDT
160 170 180 190 200
GAVDLRVTNA MFRNNIANDG KGGAIYTINN DVYLSDVIFD NNQAYTSTSY
210 220 230 240 250
SDGDGGAIDV TDNNSDSKHP SGYTIVNNTA FTNNTAEGYG GAIYTNSVTA
260 270 280 290 300
PYLIDISVDD SYSQNGGVLV DENNSAAGYG DGPSSAAGGF MYLGLSEVTF
310 320 330 340 350
DIADGKTLVI GNTENDGAVD SIAGTGLITK TGSGDLVLNA DNNDFTGEMQ
360 370 380 390 400
IENGEVTLGR SNSLMNVGDT HCQDDPQDCY GLTIGSIDQY QNQAELNVGS
410 420 430 440 450
TQQTFVHALT GFQNGTLNID AGGNVTVNQG SFAGIIEGAG QLTIAQNGSY
460 470 480 490 500
VLAGAQSMAL TGDIVVDDGA VLSLEGDAAD LTALQDDPQS IVLNGGVLDL
510 520 530 540 550
SDFSTWQSGT SYNDGLEVSG SSGTVIGSQD VVDLAGGDNL HIGGDGKDGV
560 570 580 590 600
YVVVDASDGQ VSLANNNSYL GTTQIASGTL MVSDNSQLGD THYNRQVIFT
610 620 630 640 650
DKQQESVMEI TSDVDTRSDA AGHGRDIEMR ADGEVAVDAG VDTQWGALMA
660 670 680 690 700
DSSGQHQDEG STLTKTGAGT LELTASGTTQ SAVRVEEGTL KGDVADILPY
710 720 730 740 750
ASSLWVGDGA TFVTGADQDI QSIDAISSGT IDISDGTVLR LTGQDTSVAL
760 770 780 790 800
NASLFNGDGT LVNATDGVTL TGELNTNLET DSLTYLSNVT VNGNLTNTSG
810 820 830 840 850
AVSLQNGVAG DTLTVNGDYT GGGTLLLDSE LNGDDSVSDQ LVMNGNTAGN
860 870 880 890 900
TTVVVNSITG IGEPTSTGIK VVDFAADPTQ FQNNAQFSLA GSGYVNMGAY
910 920 930 940 950
DYTLVEDNND WYLRSQEVTP PSPPDPDPTP DPDPTPDPDP TPDPEPTPAY
960 970 980 990 1000
QPVLNAKVGG YLNNLRAANQ AFMMERRDHA GGDGQTLNLR VIGGDYHYTA
1010 1020 1030 1040 1050
AGQLAQHEDT STVQLSGDLF SGRWGTDGEW MLGIVGGYSD NQGDSRSNMT
1060 1070 1080 1090 1100
GTRADNQNHG YAVGLTSSWF QHGNQKQGAW LDSWLQYAWF SNDVSEQEDG
1110 1120 1130 1140 1150
TDHYHSSGII ASLEAGYQWL PGRGVVIEPQ AQVIYQGVQQ DDFTAANRAR
1160 1170 1180 1190 1200
VSQSQGDDIQ TRLGLHSEWR TAVHVIPTLD LNYYHDPHST EIEEDGSTIS
1210 1220 1230 1240 1250
DDAVKQRGEI KVGVTGNISQ RVSLRGSVAW QKGSDDFAQT AGFLSMTVKW
Length:1,250
Mass (Da):131,153
Last modified:November 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i17F98C05E299FC95
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence K02672 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti28 – 30AAV → RGRS in K02672 (PubMed:6087316).Curated3
Sequence conflicti40K → Q in K02672 (PubMed:6087316).Curated1
Sequence conflicti65 – 66LV → PG in K02672 (PubMed:6087316).Curated2
Sequence conflicti431S → Q in K02672 (PubMed:6087316).Curated1
Sequence conflicti433 – 434AG → SA in K02672 (PubMed:6087316).Curated2
Sequence conflicti478A → R in K02672 (PubMed:6087316).Curated1
Sequence conflicti773E → S in K02672 (PubMed:6087316).Curated1
Sequence conflicti853V → M in K02672 (PubMed:6087316).Curated1
Sequence conflicti923 – 924PP → AT in K02672 (PubMed:6087316).Curated2
Sequence conflicti948 – 994PAYQP…RVIGG → LLTSRC in AAA74094 (Ref. 5) CuratedAdd BLAST47

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75293.1
AP009048 Genomic DNA Translation: BAA16050.2
K02672 Genomic DNA No translation available.
U30459 Genomic DNA Translation: AAA74094.1
Y00544 Genomic DNA No translation available.

Protein sequence database of the Protein Information Resource

More...
PIRi
G64993

NCBI Reference Sequences

More...
RefSeqi
NP_416736.1, NC_000913.3
WP_001220077.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75293; AAC75293; b2233
BAA16050; BAA16050; BAA16050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57727971
946595

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW2227
eco:b2233

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|511145.12.peg.2322

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75293.1
AP009048 Genomic DNA Translation: BAA16050.2
K02672 Genomic DNA No translation available.
U30459 Genomic DNA Translation: AAA74094.1
Y00544 Genomic DNA No translation available.
PIRiG64993
RefSeqiNP_416736.1, NC_000913.3
WP_001220077.1, NZ_LN832404.1

3D structure databases

SMRiP45508
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4262133, 267 interactors
IntActiP45508, 6 interactors
STRINGi511145.b2233

Protein family/group databases

MEROPSiU69.A11
TCDBi1.B.12.1.5, the autotransporter-1 (at-1) family

Proteomic databases

PaxDbiP45508
PRIDEiP45508

Genome annotation databases

EnsemblBacteriaiAAC75293; AAC75293; b2233
BAA16050; BAA16050; BAA16050
GeneIDi57727971
946595
KEGGiecj:JW2227
eco:b2233
PATRICifig|511145.12.peg.2322

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB2695

Phylogenomic databases

eggNOGiCOG3468, Bacteria
HOGENOMiCLU_003013_0_0_6
PhylomeDBiP45508

Enzyme and pathway databases

BioCyciEcoCyc:EG12850-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P45508

Family and domain databases

CDDicd01344, PL2_Passenger_AT, 1 hit
Gene3Di2.160.20.20, 1 hit
2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR043990, AC_1
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR013425, Autotrns_rpt
IPR006315, OM_autotransptr_brl
IPR012332, P22_tailspike-like_C_sf
IPR011050, Pectin_lyase_fold/virulence
IPR003368, POMP_repeat
PfamiView protein in Pfam
PF18883, AC_1, 1 hit
PF03797, Autotransporter, 1 hit
PF02415, Chlam_PMP, 3 hits
PF12951, PATR, 3 hits
SMARTiView protein in SMART
SM00869, Autotransporter, 1 hit
SUPFAMiSSF103515, SSF103515, 1 hit
SSF51126, SSF51126, 2 hits
TIGRFAMsiTIGR01414, autotrans_barl, 1 hit
TIGR02601, autotrns_rpt, 1 hit
TIGR01376, POMP_repeat, 2 hits
PROSITEiView protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYFAL_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P45508
Secondary accession number(s): P39441
, P45506, P45507, P76468, P77487
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1997
Last modified: April 7, 2021
This is version 163 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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