UniProtKB - P45394 (YRBG_ECOLI)
Protein
Inner membrane protein YrbG
Gene
yrbG
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- calcium, potassium:sodium antiporter activity Source: GO_Central
- calcium channel activity Source: GO_Central
GO - Biological processi
- calcium ion transmembrane transport Source: GO_Central
- cellular calcium ion homeostasis Source: GO_Central
Enzyme and pathway databases
BioCyci | EcoCyc:YRBG-MONOMER |
Protein family/group databases
TCDBi | 2.A.19.5.1, the ca(2+):cation antiporter (caca) family |
Names & Taxonomyi
Protein namesi | Recommended name: Inner membrane protein YrbG |
Gene namesi | Name:yrbG Ordered Locus Names:b3196, JW3163 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: EcoliWiki
- plasma membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 5 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 6 – 26 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 27 – 37 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 38 – 58 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 59 – 67 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 68 – 88 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 89 – 104 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 105 – 125 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 126 | PeriplasmicSequence analysis | 1 | |
Transmembranei | 127 – 147 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 148 – 169 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 170 – 190 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 191 – 198 | PeriplasmicSequence analysis | 8 | |
Transmembranei | 199 – 219 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 220 – 243 | CytoplasmicSequence analysisAdd BLAST | 24 | |
Transmembranei | 244 – 264 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 265 – 269 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 270 – 290 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 291 – 302 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 303 – 323 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 324 – 325 | PeriplasmicSequence analysis | 2 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000209507 | 1 – 325 | Inner membrane protein YrbGAdd BLAST | 325 |
Proteomic databases
PaxDbi | P45394 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261579, 6 interactors |
STRINGi | 511145.b3196 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0530, Bacteria |
HOGENOMi | CLU_007948_0_2_6 |
InParanoidi | P45394 |
PhylomeDBi | P45394 |
Family and domain databases
InterProi | View protein in InterPro IPR004481, K/Na/Ca-exchanger IPR004837, NaCa_Exmemb |
PANTHERi | PTHR10846, PTHR10846, 2 hits |
Pfami | View protein in Pfam PF01699, Na_Ca_ex, 2 hits |
TIGRFAMsi | TIGR00367, TIGR00367, 1 hit |
i Sequence
Sequence statusi: Complete.
P45394-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLATALLIV GLLLVVYSAD RLVFAASILC RTFGIPPLII GMTVVSIGTS
60 70 80 90 100
LPEVIVSLAA SLHEQRDLAV GTALGSNIIN ILLILGLAAL VRPFTVHSDV
110 120 130 140 150
LRRELPLMLL VSVVAGSVLY DGQLSRSDGI FLLFLAVLWL LFIVKLARQA
160 170 180 190 200
ERQGTDSLTR EQLAELPRDG GLPVAFLWLG IALIIMPVAT RMVVDNATVL
210 220 230 240 250
ANYFAISELT MGLTAIAIGT SLPELATAIA GVRKGENDIA VGNIIGANIF
260 270 280 290 300
NIVIVLGLPA LITPGEIDPL AYSRDYSVML LVSIIFALLC WRRSPQPGRG
310 320
VGVLLTGGFI VWLAMLYWLS PILVE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA57997.1 U00096 Genomic DNA Translation: AAC76228.1 AP009048 Genomic DNA Translation: BAE77240.1 |
PIRi | F65110 |
RefSeqi | NP_417663.1, NC_000913.3 WP_000922901.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76228; AAC76228; b3196 BAE77240; BAE77240; BAE77240 |
GeneIDi | 57728532 947730 |
KEGGi | ecj:JW3163 eco:b3196 |
PATRICi | fig|1411691.4.peg.3535 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA57997.1 U00096 Genomic DNA Translation: AAC76228.1 AP009048 Genomic DNA Translation: BAE77240.1 |
PIRi | F65110 |
RefSeqi | NP_417663.1, NC_000913.3 WP_000922901.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261579, 6 interactors |
STRINGi | 511145.b3196 |
Protein family/group databases
TCDBi | 2.A.19.5.1, the ca(2+):cation antiporter (caca) family |
Proteomic databases
PaxDbi | P45394 |
Genome annotation databases
EnsemblBacteriai | AAC76228; AAC76228; b3196 BAE77240; BAE77240; BAE77240 |
GeneIDi | 57728532 947730 |
KEGGi | ecj:JW3163 eco:b3196 |
PATRICi | fig|1411691.4.peg.3535 |
Organism-specific databases
EchoBASEi | EB2654 |
Phylogenomic databases
eggNOGi | COG0530, Bacteria |
HOGENOMi | CLU_007948_0_2_6 |
InParanoidi | P45394 |
PhylomeDBi | P45394 |
Enzyme and pathway databases
BioCyci | EcoCyc:YRBG-MONOMER |
Miscellaneous databases
PROi | PR:P45394 |
Family and domain databases
InterProi | View protein in InterPro IPR004481, K/Na/Ca-exchanger IPR004837, NaCa_Exmemb |
PANTHERi | PTHR10846, PTHR10846, 2 hits |
Pfami | View protein in Pfam PF01699, Na_Ca_ex, 2 hits |
TIGRFAMsi | TIGR00367, TIGR00367, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YRBG_ECOLI | |
Accessioni | P45394Primary (citable) accession number: P45394 Secondary accession number(s): Q2M916 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | February 10, 2021 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families