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UniProtKB - P44969 (IGA0_HAEIN)

Entry version 141 (07 Apr 2021)
Sequence version 1 (01 Nov 1995)
Previous versions | rss
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Protein

Immunoglobulin A1 protease autotransporter

Gene

iga

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known. EC:3.4.21.72

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei288Curated1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Serine protease
Biological processVirulence

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		HINF71421:G1GJ1-1032-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		3.4.21.72, 2529

Protein family/group databases

MEROPS protease database

More...MEROPSi		S06.007

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Immunoglobulin A1 protease autotransporter (EC:3.4.21.72)
Cleaved into the following 2 chains:
Immunoglobulin A1 protease
Short name:
IGA1 protease
Immunoglobulin A1 protease translocator
Alternative name(s):
Helper peptide
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:iga
Synonyms:iga1
Ordered Locus Names:HI_0990
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri71421 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000579 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell outer membrane, Membrane, Periplasm, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000038759826 – 1694Immunoglobulin A1 protease autotransporterAdd BLAST1669
ChainiPRO_000002695826 – 1014Immunoglobulin A1 proteaseAdd BLAST989
ChainiPRO_00000269591015 – 1694Immunoglobulin A1 protease translocatorSequence analysisAdd BLAST680

Keywords - PTMi

Zymogen

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		71421.HI_0990

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11694
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P44969

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P44969

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 332Peptidase S6PROSITE-ProRule annotationAdd BLAST307
Domaini1442 – 1694AutotransporterPROSITE-ProRule annotationAdd BLAST253

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space. Then, insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface, with subsequent cleavage (By similarity).By similarity

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG3266, Bacteria
COG3468, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004023_0_0_6

Identification of Orthologs from Complete Genome Data

More...OMAi		AAPQDYM

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.160.20.20, 1 hit
2.40.128.130, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR012332, P22_tailspike-like_C_sf
IPR011050, Pectin_lyase_fold/virulence
IPR000710, Peptidase_S6
IPR030396, Peptidase_S6_dom
IPR004899, Pertactin_central

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03797, Autotransporter, 1 hit
PF02395, Peptidase_S6, 1 hit
PF03212, Pertactin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00921, IGASERPTASE

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00869, Autotransporter, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103515, SSF103515, 1 hit
SSF51126, SSF51126, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit
PS51691, PEPTIDASE_S6, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P44969-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLNKKFKLNF IALTVAYALT PYTEAALVRD DVDYQIFRDF AENKGRFSVG 
        60         70         80         90        100
ATNVEVRDKN NHSLGNVLPN GIPMIDFSVV DVDKRIATLI NPQYVVGVKH 
       110        120        130        140        150
VSNGVSELHF GNLNGNMNNG NAKSHRDVSS EENRYFSVEK NEYPTKLNGK 
       160        170        180        190        200
AVTTEDQTQK RREDYYMPRL DKFVTEVAPI EASTASSDAG TYNDQNKYPA 
       210        220        230        240        250
FVRLGSGSQF IYKKGDNYSL ILNNHEVGGN NLKLVGDAYT YGIAGTPYKV 
       260        270        280        290        300
NHENNGLIGF GNSKEEHSDP KGILSQDPLT NYAVLGDSGS PLFVYDREKG 
       310        320        330        340        350
KWLFLGSYDF WAGYNKKSWQ EWNIYKPEFA KTVLDKDTAG SLTGSNTQYN 
       360        370        380        390        400
WNPTGKTSVI SNGSESLNVD LFDSSQDTDS KKNNHGKSVT LRGSGTLTLN 
       410        420        430        440        450
NNIDQGAGGL FFEGDYEVKG TSDSTTWKGA GVSVADGKTV TWKVHNPKSD 
       460        470        480        490        500
RLAKIGKGTL IVEGKGENKG SLKVGDGTVI LKQQADANNK VKAFSQVGIV 
       510        520        530        540        550
SGRSTVVLND DKQVDPNSIY FGFRGGRLDA NGNNLTFEHI RNIDDGARLV 
       560        570        580        590        600
NHNTSKTSTV TITGESLITD PNTITPYNID APDEDNPYAF RRIKDGGQLY 
       610        620        630        640        650
LNLENYTYYA LRKGASTRSE LPKNSGESNE NWLYMGKTSD EAKRNVMNHI 
       660        670        680        690        700
NNERMNGFNG YFGEEEGKNN GNLNVTFKGK SEQNRFLLTG GTNLNGDLKV 
       710        720        730        740        750
EKGTLFLSGR PTPHARDIAG ISSTKKDQHF AENNEVVVED DWINRNFKAT 
       760        770        780        790        800
NINVTNNATL YSGRNVANIT SNITASDNAK VHIGYKAGDT VCVRSDYTGY 
       810        820        830        840        850
VTCTTDKLSD KALNSFNATN VSGNVNLSGN ANFVLGKANL FGTISGTGNS 
       860        870        880        890        900
QVRLTENSHW HLTGDSNVNQ LNLDKGHIHL NAQNDANKVT TYNTLTVNSL 
       910        920        930        940        950
SGNGSFYYLT DLSNKQGDKV VVTKSATGNF TLQVADKTGE PTKNELTLFD 
       960        970        980        990       1000
ASNATRNNLN VSLVGNTVDL GAWKYKLRNV NGRYDLYNPE VEKRNQTVDT 
      1010       1020       1030       1040       1050
TNITTPNNIQ ADVPSVPSNN EEIARVETPV PPPAPATPSE TTETVAENSK 
      1060       1070       1080       1090       1100
QESKTVEKNE QDATETTAQN GEVAEEAKPS VKANTQTNEV AQSGSETEET 
      1110       1120       1130       1140       1150
QTTEIKETAK VEKEEKAKVE KDEIQEAPQM ASETSPKQAK PAPKEVSTDT 
      1160       1170       1180       1190       1200
KVEETQVQAQ PQTQSTTVAA AEATSPNSKP AEETQPSEKT NAEPVTPVVS 
      1210       1220       1230       1240       1250
KNQTENTTDQ PTEREKTAKV ETEKTQEPPQ VASQASPKQE QSETVQPQAV 
      1260       1270       1280       1290       1300
LESENVPTVN NAEEVQAQLQ TQTSATVSTK QPAPENSINT GSATAITETA 
      1310       1320       1330       1340       1350
EKSDKPQTET AASTEDASQH KANTVADNSV ANNSESSDPK SRRRRSISQP 
      1360       1370       1380       1390       1400
QETSAEETTA ASTDETTIAD NSKRSKPNRR SRRSVRSEPT VTNGSDRSTV 
      1410       1420       1430       1440       1450
ALRDLTSTNT NAVISDAMAK AQFVALNVGK AVSQHISQLE MNNEGQYNVW 
      1460       1470       1480       1490       1500
VSNTSMNENY SSSQYRRFSS KSTQTQLGWD QTISNNVQLG GVFTYVRNSN 
      1510       1520       1530       1540       1550
NFDKASSKNT LAQVNFYSKY YADNHWYLGI DLGYGKFQSN LKTNHNAKFA 
      1560       1570       1580       1590       1600
RHTAQFGLTA GKAFNLGNFG ITPIVGVRYS YLSNANFALA KDRIKVNPIS 
      1610       1620       1630       1640       1650
VKTAFAQVDL SYTYHLGEFS VTPILSARYD TNQGSGKINV NQYDFAYNVE 
      1660       1670       1680       1690 
NQQQYNAGLK LKYHNVKLSL IGGLTKAKQA EKQKTAELKL SFSF
Length:1,694
Mass (Da):185,539
Last modified:November 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC52427013F93178C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti253 – 254EN → GV in CAB56789 (Ref. 1) Curated2
Sequence conflicti272G → A in CAB56789 (Ref. 1) Curated1
Sequence conflicti464G → E in CAB56789 (Ref. 1) Curated1
Sequence conflicti866S → T in CAB56789 (Ref. 1) Curated1
Sequence conflicti1036A → D in CAB56789 (Ref. 1) Curated1
Sequence conflicti1074A → G in CAB56789 (Ref. 1) Curated1
Sequence conflicti1421A → G in CAB56789 (Ref. 1) Curated1
Sequence conflicti1545H → T in CAB56789 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X59800 Genomic DNA Translation: CAB56789.1
L42023 Genomic DNA Translation: AAC22651.1

Protein sequence database of the Protein Information Resource

More...PIRi		H64106

NCBI Reference Sequences

More...RefSeqi		NP_439153.1, NC_000907.1
WP_005693332.1, NC_000907.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC22651; AAC22651; HI_0990

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hin:HI_0990

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|71421.8.peg.1033

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59800 Genomic DNA Translation: CAB56789.1
L42023 Genomic DNA Translation: AAC22651.1
PIRiH64106
RefSeqiNP_439153.1, NC_000907.1
WP_005693332.1, NC_000907.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3H09X-ray1.75A/B26-1014[»]
SMRiP44969
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi71421.HI_0990

Protein family/group databases

MEROPSiS06.007

Genome annotation databases

EnsemblBacteriaiAAC22651; AAC22651; HI_0990
KEGGihin:HI_0990
PATRICifig|71421.8.peg.1033

Phylogenomic databases

eggNOGiCOG3266, Bacteria
COG3468, Bacteria
HOGENOMiCLU_004023_0_0_6
OMAiAAPQDYM

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-1032-MONOMER
BRENDAi3.4.21.72, 2529

Miscellaneous databases

EvolutionaryTraceiP44969

Family and domain databases

Gene3Di2.160.20.20, 1 hit
2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR012332, P22_tailspike-like_C_sf
IPR011050, Pectin_lyase_fold/virulence
IPR000710, Peptidase_S6
IPR030396, Peptidase_S6_dom
IPR004899, Pertactin_central
PfamiView protein in Pfam
PF03797, Autotransporter, 1 hit
PF02395, Peptidase_S6, 1 hit
PF03212, Pertactin, 1 hit
PRINTSiPR00921, IGASERPTASE
SMARTiView protein in SMART
SM00869, Autotransporter, 1 hit
SUPFAMiSSF103515, SSF103515, 1 hit
SSF51126, SSF51126, 1 hit
PROSITEiView protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit
PS51691, PEPTIDASE_S6, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIGA0_HAEIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P44969
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 7, 2021
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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