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UniProtKB - P44530 (Y125_HAEIN)
Protein
Putative permease HI_0125
Gene
HI_0125
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 315 – 322 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- guanine transmembrane transporter activity Source: GO_Central
- purine nucleobase transmembrane transporter activity Source: GO_Central
Keywordsi
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Putative permease HI_0125 |
Gene namesi | Ordered Locus Names:HI_0125 |
Organismi | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
Taxonomic identifieri | 71421 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 41 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 51 – 71 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 73 – 93 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 97 – 117 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 137 – 157 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 167 – 187 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 195 – 215 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 238 – 258 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 296 – 316 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 326 – 346 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 347 – 367 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 386 – 406 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 418 – 438 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000169722 | 1 – 438 | Putative permease HI_0125Add BLAST | 438 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2252, Bacteria |
HOGENOMi | CLU_024508_0_1_6 |
OMAi | PDAMGMV |
PhylomeDBi | P44530 |
Family and domain databases
InterProi | View protein in InterPro IPR045018, Azg-like IPR006043, NCS2 |
PANTHERi | PTHR43337, PTHR43337, 1 hit |
Pfami | View protein in Pfam PF00860, Xan_ur_permease, 1 hit |
i Sequence
Sequence statusi: Complete.
P44530-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPTLEKTFEL KQRGSTVRQE IIAGLTTFLA MVYSVIVVPN MLGAAGFPAE
60 70 80 90 100
SVFIATCLVA GLGSILIGLW ANAPMAIGCA ISLTAFTAFS LVIGQKVAIP
110 120 130 140 150
VALGAVFLMG VVFTLISTTG IRAWILRNLP SNIAHGAGIG IGLFLLLIAA
160 170 180 190 200
NGVGLVVSNQ AGLPVKLGDF TSFPVMMSLI GLALIIGLEK MKIKGGILWV
210 220 230 240 250
IIAITIVGLI FDPNVKFGGE IFKMPTFGEN SLFLQLDFMG ALQPAILPVV
260 270 280 290 300
FALVMTAVFD ATGTIRAVAG QADLLDKDGQ IINGGKALTS DSISSLFSGL
310 320 330 340 350
FGTAPAAVYI ESAAGTAAGG KTGITAIVVG VLFLLMLFFQ PLAFLVPGYA
360 370 380 390 400
TAPALMYVGL LMLSNVSKLD FDDFVGAMSG LICAVFIVLT ANIVTGIMLG
410 420 430
FAALVIGRIV SGDIKRLNVG TVIIAIVLVA FYAGGWAI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L42023 Genomic DNA Translation: AAC21799.1 |
PIRi | C64143 |
RefSeqi | NP_438297.1, NC_000907.1 WP_005694416.1, NC_000907.1 |
Genome annotation databases
EnsemblBacteriai | AAC21799; AAC21799; HI_0125 |
KEGGi | hin:HI_0125 |
PATRICi | fig|71421.8.peg.129 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L42023 Genomic DNA Translation: AAC21799.1 |
PIRi | C64143 |
RefSeqi | NP_438297.1, NC_000907.1 WP_005694416.1, NC_000907.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 71421.HI_0125 |
Genome annotation databases
EnsemblBacteriai | AAC21799; AAC21799; HI_0125 |
KEGGi | hin:HI_0125 |
PATRICi | fig|71421.8.peg.129 |
Phylogenomic databases
eggNOGi | COG2252, Bacteria |
HOGENOMi | CLU_024508_0_1_6 |
OMAi | PDAMGMV |
PhylomeDBi | P44530 |
Family and domain databases
InterProi | View protein in InterPro IPR045018, Azg-like IPR006043, NCS2 |
PANTHERi | PTHR43337, PTHR43337, 1 hit |
Pfami | View protein in Pfam PF00860, Xan_ur_permease, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y125_HAEIN | |
Accessioni | P44530Primary (citable) accession number: P44530 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | February 23, 2022 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families