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UniProtKB - P44460 (CITE_HAEIN)
Protein
Citrate lyase subunit beta
Gene
citE
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Functioni
Represents a citryl-ACP lyase.
By similarityCatalytic activityi
Cofactori
Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 66 | SubstrateBy similarity | 1 | |
Metal bindingi | 129 | MagnesiumBy similarity | 1 | |
Binding sitei | 129 | SubstrateBy similarity | 1 | |
Metal bindingi | 156 | MagnesiumBy similarity | 1 |
GO - Molecular functioni
- citrate (pro-3S)-lyase activity Source: UniProtKB-EC
- citryl-CoA lyase activity Source: UniProtKB-EC
- magnesium ion binding Source: GO_Central
GO - Biological processi
- acetyl-CoA metabolic process Source: InterPro
- oxaloacetate metabolic process Source: GO_Central
Keywordsi
Molecular function | Lyase |
Ligand | Magnesium, Metal-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:citE Ordered Locus Names:HI_0023 |
Organismi | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
Taxonomic identifieri | 71421 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
Other locations
- ATP-independent citrate lyase complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000089758 | 1 – 291 | Citrate lyase subunit betaAdd BLAST | 291 |
Interactioni
Subunit structurei
Oligomer with a subunit composition of (alpha,beta,gamma)6.
By similarityProtein-protein interaction databases
STRINGi | 71421.HI_0023 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG2301, Bacteria |
HOGENOMi | CLU_044864_0_0_6 |
OMAi | AWLFCPA |
PhylomeDBi | P44460 |
Family and domain databases
Gene3Di | 3.20.20.60, 1 hit |
InterProi | View protein in InterPro IPR005000, Aldolase/citrate-lyase_domain IPR011206, Citrate_lyase_beta/mcl1/mcl2 IPR006475, Citrate_lyase_beta_bac IPR015813, Pyrv/PenolPyrv_Kinase-like_dom IPR040442, Pyrv_Kinase-like_dom_sf |
Pfami | View protein in Pfam PF03328, HpcH_HpaI, 1 hit |
PIRSFi | PIRSF015582, Cit_lyase_B, 1 hit |
SUPFAMi | SSF51621, SSF51621, 1 hit |
TIGRFAMsi | TIGR01588, citE, 1 hit |
i Sequence
Sequence statusi: Complete.
P44460-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLRRSMLFV PGSNAAMLSN SFIYKPDSIM FDLEDAVALK EKDSARLLVA
60 70 80 90 100
HALQHPLYKE IETVVRVNPL DSEFGLLDLN SVVRAGVDVV RMPKTESAQD
110 120 130 140 150
VLDMDHAITE IEKACGREAG STKMLAAIES PLGITQANQI AFASKRLIGI
160 170 180 190 200
ALGAEDYVRN LKTERSPEGI ELLFARCSIL QAARAAGIQA FDTVYSNANN
210 220 230 240 250
EEGFLKEAAL IKQLGFDGKS LINPRQIELL HNLFAPTQKD VEQAKRIIEA
260 270 280 290
AVEAERQGAG VVSLNGKMID APIIDRAKLV LERAKSGIRE E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L42023 Genomic DNA Translation: AAC21701.1 |
PIRi | D64043 |
RefSeqi | NP_438196.2, NC_000907.1 WP_005693883.1, NC_000907.1 |
Genome annotation databases
EnsemblBacteriai | AAC21701; AAC21701; HI_0023 |
KEGGi | hin:HI_0023 |
PATRICi | fig|71421.8.peg.23 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L42023 Genomic DNA Translation: AAC21701.1 |
PIRi | D64043 |
RefSeqi | NP_438196.2, NC_000907.1 WP_005693883.1, NC_000907.1 |
3D structure databases
SMRi | P44460 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 71421.HI_0023 |
Genome annotation databases
EnsemblBacteriai | AAC21701; AAC21701; HI_0023 |
KEGGi | hin:HI_0023 |
PATRICi | fig|71421.8.peg.23 |
Phylogenomic databases
eggNOGi | COG2301, Bacteria |
HOGENOMi | CLU_044864_0_0_6 |
OMAi | AWLFCPA |
PhylomeDBi | P44460 |
Family and domain databases
Gene3Di | 3.20.20.60, 1 hit |
InterProi | View protein in InterPro IPR005000, Aldolase/citrate-lyase_domain IPR011206, Citrate_lyase_beta/mcl1/mcl2 IPR006475, Citrate_lyase_beta_bac IPR015813, Pyrv/PenolPyrv_Kinase-like_dom IPR040442, Pyrv_Kinase-like_dom_sf |
Pfami | View protein in Pfam PF03328, HpcH_HpaI, 1 hit |
PIRSFi | PIRSF015582, Cit_lyase_B, 1 hit |
SUPFAMi | SSF51621, SSF51621, 1 hit |
TIGRFAMsi | TIGR01588, citE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CITE_HAEIN | |
Accessioni | P44460Primary (citable) accession number: P44460 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | September 29, 2021 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families