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Protein

Type-2 restriction enzyme HindII

Gene

hindIIR

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processRestriction system

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-525-MONOMER

Protein family/group databases

REBASEi1150 HindII

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme HindII (EC:3.1.21.4)
Short name:
R.HindII
Alternative name(s):
Endonuclease HindII
Type II restriction enzyme HindII
Gene namesi
Name:hindIIR
Ordered Locus Names:HI_0512
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000773202 – 258Type-2 restriction enzyme HindIIAdd BLAST257

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0512

Structurei

3D structure databases

ProteinModelPortaliP44413
SMRiP44413
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4106KR2 Bacteria
ENOG410YBKR LUCA
KOiK01155

Family and domain databases

Gene3Di3.40.600.10, 1 hit
InterProiView protein in InterPro
IPR037057 DNA_rep_MutH/RE_typeII_sf
IPR011335 Restrct_endonuc-II-like
IPR015307 Restrct_endonuc_II_HincII
PfamiView protein in Pfam
PF09226 Endonuc-HincII, 1 hit
SUPFAMiSSF52980 SSF52980, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P44413-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFIKPIYQD INSILIGQKV KRPKSGTLSG HAAGEPFEKL VYKFLKENLS
60 70 80 90 100
DLTFKQYEYL NDLFMKKPAI IGHEARYKLF NSPTLLFLLS RGKAATENWS
110 120 130 140 150
IENLFEEKQN DTADILLVKD QFYELLDVKT RNISKSAQAP NIISAYKLAQ
160 170 180 190 200
TCAKMIDNKE FDLFDINYLE VDWELNGEDL VCVSTSFAEL FKSEPSELYI
210 220 230 240 250
NWAAAMQIQF HVRDLDQGFN GTREEWAKSY LKHFVTQAEQ RAISMIDKFV

KPFKKYIL
Length:258
Mass (Da):29,929
Last modified:January 23, 2007 - v2
Checksum:i6BE104A1D1B63238
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC22170.1
PIRiE64073
RefSeqiNP_438670.1, NC_000907.1
WP_005693662.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22170; AAC22170; HI_0512
GeneIDi950710
KEGGihin:HI0512
PATRICifig|71421.8.peg.531

Similar proteinsi

Entry informationi

Entry nameiT2D2_HAEIN
AccessioniPrimary (citable) accession number: P44413
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

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