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Protein

Probable bacterial non-heme ferritin

Gene

ftnA

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Iron-storage protein.By similarity

Catalytic activityi

4 Fe2+ + O2 + 6 H2O = 4 (FeO(OH)) + 8 H+.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 2PROSITE-ProRule annotation1
Metal bindingi53Iron 1PROSITE-ProRule annotation1
Metal bindingi94Iron 2PROSITE-ProRule annotation1
Metal bindingi127Iron 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processIron storage
LigandIron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable bacterial non-heme ferritin (EC:1.16.3.2)
Gene namesi
Name:ftnA
Synonyms:rsgA-A
Ordered Locus Names:HI_1384
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010931 – 162Probable bacterial non-heme ferritinAdd BLAST162

Interactioni

Subunit structurei

Homooligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms.By similarity

Protein-protein interaction databases

STRINGi71421.HI1384

Structurei

3D structure databases

ProteinModelPortaliP43707
SMRiP43707
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 145Ferritin-like diironPROSITE-ProRule annotationAdd BLAST145

Sequence similaritiesi

Belongs to the ferritin family. Prokaryotic subfamily.Curated

Phylogenomic databases

eggNOGiENOG41090A1 Bacteria
COG1528 LUCA
KOiK02217
OMAiCEDKGFE

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS50905 FERRITIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P43707-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNQIIINKL NDQINLEFYS SNVYLQMSAW CSKHGYEGAA TFLLRHADEE
60 70 80 90 100
LEHMQKLFNY VSETSGMPIL GKIDAPKHDY SSLREVFEIT LEHEKLVTSK
110 120 130 140 150
INELVEVTFE SKDYSTFNFL QWYVAEQHEE EKLFSGIIDR FNLVGEDGKG
160
LFFIDRELAT LE
Length:162
Mass (Da):18,896
Last modified:June 1, 2001 - v2
Checksum:iCDF256FA7F02799A
GO

Sequence cautioni

The sequence AAC23031 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC23031.1 Different initiation.
PIRiA64121
RefSeqiNP_439536.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC23031; AAC23031; HI_1384
GeneIDi950297
KEGGihin:HI1384
PATRICifig|71421.8.peg.1440

Similar proteinsi

Entry informationi

Entry nameiFTN1_HAEIN
AccessioniPrimary (citable) accession number: P43707
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 1, 2001
Last modified: November 22, 2017
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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