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UniProtKB - P43678 (KAS1_STRRM)
Protein
Oxytetracycline polyketide putative beta-ketoacyl synthase 1
Gene
N/A
Organism
Streptomyces rimosus
Status
Functioni
: oxytetracycline biosynthesis Pathwayi
This protein is involved in the pathway oxytetracycline biosynthesis, which is part of Antibiotic biosynthesis.View all proteins of this organism that are known to be involved in the pathway oxytetracycline biosynthesis and in Antibiotic biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 173 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- 3-oxoacyl-[acyl-carrier-protein] synthase activity Source: InterPro
GO - Biological processi
- antibiotic biosynthetic process Source: UniProtKB-KW
- fatty acid biosynthetic process Source: InterPro
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Antibiotic biosynthesis |
Enzyme and pathway databases
UniPathwayi | UPA00926 |
Names & Taxonomyi
Protein namesi | Recommended name: Oxytetracycline polyketide putative beta-ketoacyl synthase 1 |
Organismi | Streptomyces rimosus |
Taxonomic identifieri | 1927 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Streptomycetales › Streptomycetaceae › Streptomyces |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000180339 | 1 – 425 | Oxytetracycline polyketide putative beta-ketoacyl synthase 1Add BLAST | 425 |
Family & Domainsi
Sequence similaritiesi
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR000794, Beta-ketoacyl_synthase IPR018201, Ketoacyl_synth_AS IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00606, B_KETOACYL_SYNTHASE, 1 hit |
i Sequence
Sequence statusi: Complete.
P43678-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKIHDARRV VITGIGVVAP GDVGTKPFWE MLTAGRTATR PISSFDASPF
60 70 80 90 100
RSQVAAECDF DPAAEGLSQR QVRAWDRTMQ FAYVAAREAL ADSGVTGEAD
110 120 130 140 150
PLRTGVMAGT ACGMTMSLDR EYAVVSDEGR LWQVDDAHGV PYLYDYFVPS
160 170 180 190 200
SMAAEIAWLA EAEGPAGVVS AGCTSGIDVL THAADLVRDG AAEVMVAGAS
210 220 230 240 250
DAAISPITVA CFDAIKATTP RNDEPETASR PFDRTRNGFV LGEGAAFFVL
260 270 280 290 300
EEYAHARRRG ARAYAEIAGY AGRCNAYSMT GLRSDGRELA EAVSRALDIA
310 320 330 340 350
RVDPSEVDYV NAHGSATKQN DLHETAAFKR SLGPHAYSVP ISSIKSMIGH
360 370 380 390 400
SLGAICALEV AASALRIEHG VIPPTANLRE PDPDCDLDYV PLVAREAEVS
410 420
TVVSVASGFG GFQSAIVLTE PGRQR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z25538 Genomic DNA Translation: CAA80985.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z25538 Genomic DNA Translation: CAA80985.1 |
3D structure databases
AlphaFoldDBi | P43678 |
SMRi | P43678 |
ModBasei | Search... |
Enzyme and pathway databases
UniPathwayi | UPA00926 |
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR000794, Beta-ketoacyl_synthase IPR018201, Ketoacyl_synth_AS IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00606, B_KETOACYL_SYNTHASE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | KAS1_STRRM | |
Accessioni | P43678Primary (citable) accession number: P43678 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families