KIR3DL2

Functionⁱ

Receptor on natural killer (NK) cells for HLA-A alleles. Inhibits the activity of NK cells thus preventing cell lysis.

GO - Biological processⁱ

cellular defense response
Source: ProtInc
Traceable author statementⁱ
- 7716543
regulation of immune response Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Receptor

Molecular function

Receptor

Enzyme and pathway databases

Reactomeⁱ	R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Reactomeⁱ

R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Killer cell immunoglobulin-like receptor 3DL2 Alternative name(s): CD158 antigen-like family member K MHC class I NK cell receptor Natural killer-associated transcript 4 Short name: NKAT-4 p70 natural killer cell receptor clone CL-5 Short name: p70 NK receptor CL-5 CD_antigen: CD158k
Gene namesⁱ	Name:KIR3DL2 Synonyms:CD158K, NKAT4
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000240403.5
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6339 KIR3DL2
MIMⁱ	604947 gene
neXtProtⁱ	NX_P43630

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	22 – 340	ExtracellularSequence analysisAdd BLAST	319
Transmembraneⁱ	341 – 360	HelicalSequence analysisAdd BLAST	20
Topological domainⁱ	361 – 455	CytoplasmicSequence analysisAdd BLAST	95

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	3812
Open Targets More...OpenTargetsⁱ	ENSG00000240403
PharmGKBⁱ	PA30124

Polymorphism and mutation databases

BioMutaⁱ	KIR3DL2
DMDMⁱ	1171729

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 21	By similarityAdd BLAST		21
ChainⁱPRO_0000015090	22 – 455	Killer cell immunoglobulin-like receptor 3DL2Add BLAST		434

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	49 ↔ 95	Curated
Disulfide bondⁱ	144 ↔ 195	By similarity
Glycosylationⁱ	179	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	239	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	244 ↔ 293	By similarity
Glycosylationⁱ	273	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	306	N-linked (GlcNAc...) asparagineSequence analysis	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbⁱ	P43630
PeptideAtlas More...PeptideAtlasⁱ	P43630
PRIDEⁱ	P43630
ProteomicsDBⁱ	55644

PTM databases

iPTMnetⁱ	P43630
PhosphoSitePlusⁱ	P43630
SwissPalmⁱ	P43630

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000240403 Expressed in 23 organ(s), highest expression level in blood
ExpressionAtlasⁱ	P43630 baseline and differential
Genevisibleⁱ	P43630 HS

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
HLA-F	P30511	6	EBI-6165894,EBI-2811134

With

Entry

#Exp.

IntAct

Notes

HLA-F

P30511

6

EBI-6165894,EBI-2811134

Protein-protein interaction databases

BioGridⁱ	110013, 22 interactors
ELMⁱ	P43630
IntActⁱ	P43630, 5 interactors
STRINGⁱ	9606.ENSP00000325525

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P43630
SMRⁱ	P43630
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	42 – 102	Ig-like C2-type 1Add BLAST	61
Domainⁱ	137 – 202	Ig-like C2-type 2Add BLAST	66
Domainⁱ	237 – 300	Ig-like C2-type 3Add BLAST	64

Sequence similaritiesⁱ

Belongs to the immunoglobulin superfamily.Curated

Keywords - Domainⁱ

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410JAMM Eukaryota ENOG410ZT7K LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119033
HOGENOMⁱ	HOG000234396
HOVERGENⁱ	HBG074353
InParanoidⁱ	P43630
KEGG Orthology (KO) More...KOⁱ	K07980
OMAⁱ	NLECPLA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0APE
PhylomeDBⁱ	P43630
TreeFamⁱ	TF352669

Family and domain databases

Gene3Dⁱ	2.60.40.10, 3 hits
InterProⁱ	View protein in InterPro IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003599 Ig_sub IPR013151 Immunoglobulin
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00047 ig, 3 hits
SMARTⁱ	View protein in SMART SM00409 IG, 3 hits
SUPFAMⁱ	SSF48726 SSF48726, 3 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 32 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: P43630-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH 
        60         70         80         90        100
YRRGFNNFML YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP 
       110        120        130        140        150
HSLTGWSAPS NPLVIMVTGN HRKPSLLAHP GPLLKSGETV ILQCWSDVMF 
       160        170        180        190        200
EHFFLHREGI SEDPSRLVGQ IHDGVSKANF SIGPLMPVLA GTYRCYGSVP 
       210        220        230        240        250
HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV TLSCSSWSSY 
       260        270        280        290        300
DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFRAL 
       310        320        330        340        350
PCVWSNSSDP LLVSVTGNPS SSWPSPTEPS SKSGICRHLH VLIGTSVVIF 
       360        370        380        390        400
LFILLLFFLL YRWCSNKKNA AVMDQEPAGD RTVNRQDSDE QDPQEVTYAQ 
       410        420        430        440        450
LDHCVFIQRK ISRPSQRPKT PLTDTSVYTE LPNAEPRSKV VSCPRAPQSG 

LEGVF

Length:455

Mass (Da):50,230

Last modified:November 1, 1995 - v1

Checksum:ⁱDB4BA6BB6B3C2945

GO

Isoform 2 (identifier: P43630-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
318-334: Missing.

« Hide

        10         20         30         40         50
MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH 
        60         70         80         90        100
YRRGFNNFML YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP 
       110        120        130        140        150
HSLTGWSAPS NPLVIMVTGN HRKPSLLAHP GPLLKSGETV ILQCWSDVMF 
       160        170        180        190        200
EHFFLHREGI SEDPSRLVGQ IHDGVSKANF SIGPLMPVLA GTYRCYGSVP 
       210        220        230        240        250
HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV TLSCSSWSSY 
       260        270        280        290        300
DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFRAL 
       310        320        330        340        350
PCVWSNSSDP LLVSVTGICR HLHVLIGTSV VIFLFILLLF FLLYRWCSNK 
       360        370        380        390        400
KNAAVMDQEP AGDRTVNRQD SDEQDPQEVT YAQLDHCVFI QRKISRPSQR 
       410        420        430 
PKTPLTDTSV YTELPNAEPR SKVVSCPRAP QSGLEGVF

Show »

Length:438

Mass (Da):48,517

Checksum:ⁱF762B713D6EB916C

GO

Computationally mapped potential isoform sequencesⁱ

There are 32 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	Q9BQU0	Q9BQU0_HUMAN	Inhibitory NK receptor Inhibitory NK receptor (KIR3DL2) (Killer cell immunoglobulin-like receptor 3DL2)	KIR3DL2 kir3d	455	Annotation score:
	A0A0G2JP93	A0A0G2JP93_HUMAN	3DL2 3DL2 (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2)	KIR3DL2 3DL2	455	Annotation score:
	Q8NHK6	Q8NHK6_HUMAN	KIR3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor 3DL2) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2) (Natural killer cell inhibitory receptor)	KIR3DL2	455	Annotation score:
	Q6H2F6	Q6H2F6_HUMAN	Killer cell immunoglobulin-like rec... Killer cell immunoglobulin-like receptor 3DL2 (Natural killer cell inhibitory receptor)	KIR3DL2	455	Annotation score:
	A0A0U5GHD6	A0A0U5GHD6_HUMAN	KIR3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2)	KIR3DL2	455	Annotation score:
	A0A0U1WNF5	A0A0U1WNF5_HUMAN	Killer cell immunoglobulin-like rec... Killer cell immunoglobulin-like receptor (Killer cell immunoglobulin-like receptor 3DL2)	KIR3DL2	455	Annotation score:
	A0A120N617	A0A120N617_HUMAN	KIR3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor 3DL2)	KIR3DL2	455	Annotation score:
	A0A0G2JMA3	A0A0G2JMA3_HUMAN	Killer cell immunoglobulin-like rec... Killer cell immunoglobulin-like receptor 3DL2	KIR3DL2	455	Annotation score:
	A0A0G2JPQ5	A0A0G2JPQ5_HUMAN	KIR3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor 3DL2)	KIR3DL2	455	Annotation score:
	A0A0G2JPA6	A0A0G2JPA6_HUMAN	Killer cell immunoglobulin-like rec... Killer cell immunoglobulin-like receptor 3DL2	KIR3DL2	438	Annotation score:
There are more potential isoformsShow all

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_010325	40	P → A2 Publications	1
Natural variantⁱVAR_010326	113	L → V2 PublicationsCorresponds to variant dbSNP:rs3188286Ensembl.	1
Natural variantⁱVAR_010327	158	E → D3 PublicationsCorresponds to variant dbSNP:rs633870Ensembl.	1
Natural variantⁱVAR_010328	166	R → H2 PublicationsCorresponds to variant dbSNP:rs1048271Ensembl.	1
Natural variantⁱVAR_010329	228	A → P1 Publication	1
Natural variantⁱVAR_010330	252	I → T1 Publication	1
Natural variantⁱVAR_049992	397	T → M. Corresponds to variant dbSNP:rs3745902Ensembl.	1
Natural variantⁱVAR_049993	439	K → Q. Corresponds to variant dbSNP:rs3745903Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_047374	318 – 334	Missing in isoform 2. 1 PublicationAdd BLAST		17

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L41270 mRNA Translation: AAA69871.1 U30272 mRNA Translation: AAB52520.1 X93595 mRNA Translation: CAA63791.1 X93596 mRNA Translation: CAA63792.1 X94373 mRNA Translation: CAA64150.1 X94374 mRNA Translation: CAA64151.1 L76665 mRNA Translation: AAB36593.1 L76666 mRNA Translation: AAB36594.1 AY789067 mRNA Translation: AAX23112.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS12906.1 [P43630-1] CCDS58677.1 [P43630-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001229796.1, NM_001242867.1 [P43630-2] NP_006728.2, NM_006737.3 [P43630-1]
UniGeneⁱ	Hs.645228 Hs.645532 Hs.654605

Genome annotation databases

Ensemblⁱ	ENST00000270442; ENSP00000270442; ENSG00000240403 [P43630-2] ENST00000326321; ENSP00000325525; ENSG00000240403 [P43630-1] ENST00000611608; ENSP00000479903; ENSG00000278809 [P43630-1] ENST00000611628; ENSP00000481662; ENSG00000278474 ENST00000611859; ENSP00000480578; ENSG00000277181 [P43630-2] ENST00000612138; ENSP00000482589; ENSG00000274722 [P43630-2] ENST00000613610; ENSP00000482301; ENSG00000278442 ENST00000613612; ENSP00000482565; ENSG00000275566 ENST00000614753; ENSP00000479299; ENSG00000276357 ENST00000617354; ENSP00000482110; ENSG00000274722 [P43630-1] ENST00000617481; ENSP00000481306; ENSG00000275083 [P43630-2] ENST00000617666; ENSP00000481209; ENSG00000278361 ENST00000617957; ENSP00000481579; ENSG00000275083 [P43630-1] ENST00000618273; ENSP00000481871; ENSG00000276739 [P43630-2] ENST00000619683; ENSP00000478251; ENSG00000275626 ENST00000620817; ENSP00000479772; ENSG00000276739 [P43630-1] ENST00000621155; ENSP00000477519; ENSG00000275416 ENST00000622024; ENSP00000479425; ENSG00000276004 ENST00000622453; ENSP00000477516; ENSG00000277181 [P43630-1] ENST00000622579; ENSP00000482655; ENSG00000278809 [P43630-2] ENST00000638330; ENSP00000492261; ENSG00000284381 [P43630-1] ENST00000638726; ENSP00000492117; ENSG00000283951 [P43630-2] ENST00000638805; ENSP00000492880; ENSG00000283975 [P43630-2] ENST00000638891; ENSP00000491303; ENSG00000284063 [P43630-1] ENST00000638970; ENSP00000491183; ENSG00000283975 [P43630-1] ENST00000639252; ENSP00000491248; ENSG00000284381 [P43630-2] ENST00000639313; ENSP00000491707; ENSG00000284063 [P43630-2] ENST00000640782; ENSP00000491436; ENSG00000283951 [P43630-1]
GeneIDⁱ	3812
KEGGⁱ	hsa:3812
UCSC genome browser More...UCSCⁱ	uc002qho.5 human [P43630-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P43630	KIR3DL2		HUMAN		455	UniRef100_P43630
KIR3DL2 (Fragment)		HUMAN		442
KIR3DL2 (Fragment)		HUMAN		431
Killer cell immunoglobulin-like receptor 3DL2 (Fragment)		HUMAN		333
Killer-cell immunoglobulin-like receptor (Fragment)		HUMAN		292
+2

Protein	Similar proteins		Species	Score	Length	Source
P43630	KIR3DL2		HUMAN		455	UniRef90_P43630
KIR3DL2 (Fragment)		HUMAN		442
KIR3DL2 (Fragment)		HUMAN		431
Killer cell immunoglobulin-like receptor 3DL2 (Fragment)		HUMAN		333
Killer-cell immunoglobulin-like receptor (Fragment)		HUMAN		292
+132

Protein	Similar proteins		Species	Score	Length	Source
P43630	Killer cell immunoglobulin-like receptor 3DL1	)	HUMAN		444	UniRef50_P43629
Uncharacterized protein		PANTR		446
Uncharacterized protein		CHLSB		457
Uncharacterized protein		Cebus capucinus imitator		457
Uncharacterized protein		SAIBB		427
+452

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L41270 mRNA Translation: AAA69871.1 U30272 mRNA Translation: AAB52520.1 X93595 mRNA Translation: CAA63791.1 X93596 mRNA Translation: CAA63792.1 X94373 mRNA Translation: CAA64150.1 X94374 mRNA Translation: CAA64151.1 L76665 mRNA Translation: AAB36593.1 L76666 mRNA Translation: AAB36594.1 AY789067 mRNA Translation: AAX23112.1
CCDSⁱ	CCDS12906.1 [P43630-1] CCDS58677.1 [P43630-2]
RefSeqⁱ	NP_001229796.1, NM_001242867.1 [P43630-2] NP_006728.2, NM_006737.3 [P43630-1]
UniGeneⁱ	Hs.645228 Hs.645532 Hs.654605

3D structure databases

ProteinModelPortalⁱ	P43630
SMRⁱ	P43630
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	110013, 22 interactors
ELMⁱ	P43630
IntActⁱ	P43630, 5 interactors
STRINGⁱ	9606.ENSP00000325525

PTM databases

iPTMnetⁱ	P43630
PhosphoSitePlusⁱ	P43630
SwissPalmⁱ	P43630

Polymorphism and mutation databases

BioMutaⁱ	KIR3DL2
DMDMⁱ	1171729

Proteomic databases

PaxDbⁱ	P43630
PeptideAtlasⁱ	P43630
PRIDEⁱ	P43630
ProteomicsDBⁱ	55644

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000270442; ENSP00000270442; ENSG00000240403 [P43630-2] ENST00000326321; ENSP00000325525; ENSG00000240403 [P43630-1] ENST00000611608; ENSP00000479903; ENSG00000278809 [P43630-1] ENST00000611628; ENSP00000481662; ENSG00000278474 ENST00000611859; ENSP00000480578; ENSG00000277181 [P43630-2] ENST00000612138; ENSP00000482589; ENSG00000274722 [P43630-2] ENST00000613610; ENSP00000482301; ENSG00000278442 ENST00000613612; ENSP00000482565; ENSG00000275566 ENST00000614753; ENSP00000479299; ENSG00000276357 ENST00000617354; ENSP00000482110; ENSG00000274722 [P43630-1] ENST00000617481; ENSP00000481306; ENSG00000275083 [P43630-2] ENST00000617666; ENSP00000481209; ENSG00000278361 ENST00000617957; ENSP00000481579; ENSG00000275083 [P43630-1] ENST00000618273; ENSP00000481871; ENSG00000276739 [P43630-2] ENST00000619683; ENSP00000478251; ENSG00000275626 ENST00000620817; ENSP00000479772; ENSG00000276739 [P43630-1] ENST00000621155; ENSP00000477519; ENSG00000275416 ENST00000622024; ENSP00000479425; ENSG00000276004 ENST00000622453; ENSP00000477516; ENSG00000277181 [P43630-1] ENST00000622579; ENSP00000482655; ENSG00000278809 [P43630-2] ENST00000638330; ENSP00000492261; ENSG00000284381 [P43630-1] ENST00000638726; ENSP00000492117; ENSG00000283951 [P43630-2] ENST00000638805; ENSP00000492880; ENSG00000283975 [P43630-2] ENST00000638891; ENSP00000491303; ENSG00000284063 [P43630-1] ENST00000638970; ENSP00000491183; ENSG00000283975 [P43630-1] ENST00000639252; ENSP00000491248; ENSG00000284381 [P43630-2] ENST00000639313; ENSP00000491707; ENSG00000284063 [P43630-2] ENST00000640782; ENSP00000491436; ENSG00000283951 [P43630-1]
GeneIDⁱ	3812
KEGGⁱ	hsa:3812
UCSCⁱ	uc002qho.5 human [P43630-1]

Organism-specific databases

CTDⁱ	3812
DisGeNETⁱ	3812
EuPathDBⁱ	HostDB:ENSG00000240403.5
GeneCardsⁱ	KIR3DL2
HGNCⁱ	HGNC:6339 KIR3DL2
MIMⁱ	604947 gene
neXtProtⁱ	NX_P43630
OpenTargetsⁱ	ENSG00000240403
PharmGKBⁱ	PA30124
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410JAMM Eukaryota ENOG410ZT7K LUCA
GeneTreeⁱ	ENSGT00760000119033
HOGENOMⁱ	HOG000234396
HOVERGENⁱ	HBG074353
InParanoidⁱ	P43630
KOⁱ	K07980
OMAⁱ	NLECPLA
OrthoDBⁱ	EOG091G0APE
PhylomeDBⁱ	P43630
TreeFamⁱ	TF352669

Enzyme and pathway databases

Reactomeⁱ	R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Reactomeⁱ

R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Miscellaneous databases

GeneWikiⁱ	KIR3DL2
GenomeRNAiⁱ	3812
Protein Ontology More...PROⁱ	PR:P43630
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000240403 Expressed in 23 organ(s), highest expression level in blood
ExpressionAtlasⁱ	P43630 baseline and differential
Genevisibleⁱ	P43630 HS

Family and domain databases

Gene3Dⁱ	2.60.40.10, 3 hits
InterProⁱ	View protein in InterPro IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003599 Ig_sub IPR013151 Immunoglobulin
Pfamⁱ	View protein in Pfam PF00047 ig, 3 hits
SMARTⁱ	View protein in SMART SM00409 IG, 3 hits
SUPFAMⁱ	SSF48726 SSF48726, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	KI3L2_HUMAN
Accessionⁱ	P43630Primary (citable) accession number: P43630 Secondary accession number(s): Q13238 Q95368
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
	Last sequence update:	November 1, 1995
	Last modified:	November 7, 2018
	This is version 177 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM
Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P43630 (KI3L2_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Killer cell immunoglobulin-like receptor 3DL2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ