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Entry version 149 (13 Nov 2019)
Sequence version 1 (01 Nov 1995)
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Protein

Uncharacterized protein YFR016C

Gene

YFR016C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-30468-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YFR016C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YFR016C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VI

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
FungiDB:YFR016C

Saccharomyces Genome Database

More...
SGDi
S000001912 YFR016C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002026861 – 1233Uncharacterized protein YFR016CAdd BLAST1233

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei180PhosphoserineCombined sources1
Modified residuei462PhosphoserineCombined sources1
Modified residuei523PhosphoserineCombined sources1
Modified residuei861PhosphothreonineCombined sources1
Modified residuei975PhosphoserineCombined sources1
Modified residuei1037PhosphoserineCombined sources1
Modified residuei1046PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P43597

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P43597

PRoteomics IDEntifications database

More...
PRIDEi
P43597

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P43597

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
31168, 46 interactors

Database of interacting proteins

More...
DIPi
DIP-4195N

Protein interaction database and analysis system

More...
IntActi
P43597, 12 interactors

STRING: functional protein association networks

More...
STRINGi
4932.YFR016C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P43597

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1132 – 1233GlutaredoxinPROSITE-ProRule annotationAdd BLAST102

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P43597

Identification of Orthologs from Complete Genome Data

More...
OMAi
DQHEKKE

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.30.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002109 Glutaredoxin
IPR036249 Thioredoxin-like_sf

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52833 SSF52833, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51354 GLUTAREDOXIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P43597-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVESLTVENQ EHNVQPPSVT SAGDSYSTLA TDLPLPSTND IIESRDQLTE
60 70 80 90 100
SDLDEAINAT ENFAQELSSQ RKSSKLKGHK KKNQGQIKAN RDRDTIVKLS
110 120 130 140 150
SSVGETEEAS TRDAISHDLE RKDDVIEIAT DTINDATESP TQIPIDVNVV
160 170 180 190 200
IKETSTNNVA EGTENVPPIK ESTGIEVGNS PITRRKKNKK KKTTNRRGRN
210 220 230 240 250
SSNPADTTDL SKQSTLDSIL VGIEEYLQED GSKNEDIKVN IVQDEPVNVE
260 270 280 290 300
KMDIRTRNES SDKTFDIDVP NKDNVDETSS KSENNINEEK AEHTLPREEN
310 320 330 340 350
EILNVNEGNA ASFKHQLEPH GLEAGDENGQ ASTKDVESES LTKNGFNFKE
360 370 380 390 400
NESKHLKAGE KQQTESDRDG ISPSVLAKNQ KETEIGKEDH VFEQKDKEDE
410 420 430 440 450
KCRKELSVNH ENNMSHNFNA AGSDSIIPPE TERETYDDET MGPTKRISDN
460 470 480 490 500
EKNLQHGTND ISVEVEKEEE EEEEEEENST FSKVKKENVT GEQEAVRNNE
510 520 530 540 550
VSGTEEESTS KGEEIMGGDE KQSEAGEKSS IIEIEGSANS AKISKDNLVL
560 570 580 590 600
EDEAEAPTQE NKPTEVVGEI DIPDAPRDDV EIVEAVEKNI IPEDLEVAKE
610 620 630 640 650
DQEGEQVKLD EPVKAMKDDK IAMRGAESIS EDMKKKQEGT AELSNEKAKK
660 670 680 690 700
EVDETARESA EGVEVEKSKT PESPKVVKRC TSGRPEDLQI NERDPEVLKE
710 720 730 740 750
DVRVPDEDVK PEIATTIENS EEEDPKSQRV QISTEQAETT QKDMGDVGST
760 770 780 790 800
TSFKEEEKPK RFEITQEGDK ITGKDTNHEH GEATEAASEN SKASDVGTAE
810 820 830 840 850
KYIEPSSESV KKDTEEDAEV ENSEKTEFIK VKAELENLDA PKEAEVTAEL
860 870 880 890 900
NKENEDVEVD TEEDAEVENS EKTEFIKVKA ELGNLDAPKE AEVTAELNKE
910 920 930 940 950
NEDVEVAATS KEDIETKCSE PAETPIEDGT CTEAEVSKKD AEAVTKEDEN
960 970 980 990 1000
MENSKIAEAL KDVTGDQEID DINISDEFQR TVELPELEKQ DIKDNKGEDK
1010 1020 1030 1040 1050
ELEVEETEKE TSLPDLVVEE NITEEKNEIK QEEEEVSQLD FNETESISKE
1060 1070 1080 1090 1100
APNNDENGFE DQSTRENPKK ASADDIFKDI LDETNEFLEQ LKIVDDSELN
1110 1120 1130 1140 1150
ALLQSLDAKD STTQTTEQSK KNNDKPQDVI TTSEIRKLNE KEPVYIYTSL
1160 1170 1180 1190 1200
AGGGFHMIPR TNRLSTILTA NRIPFTYRDL GTDDEARKVW KTFSKGRSLP
1210 1220 1230
GVVRGHNDLI GNWEEIEEAN EDYKLRELIY DTI
Length:1,233
Mass (Da):137,698
Last modified:November 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8A7CD2C6F0892F6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D50617 Genomic DNA Translation: BAA09255.1
BK006940 Genomic DNA Translation: DAA12457.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S56271

NCBI Reference Sequences

More...
RefSeqi
NP_116671.1, NM_001179981.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YFR016C_mRNA; YFR016C; YFR016C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850570

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YFR016C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA Translation: BAA09255.1
BK006940 Genomic DNA Translation: DAA12457.1
PIRiS56271
RefSeqiNP_116671.1, NM_001179981.1

3D structure databases

SMRiP43597
ModBaseiSearch...

Protein-protein interaction databases

BioGridi31168, 46 interactors
DIPiDIP-4195N
IntActiP43597, 12 interactors
STRINGi4932.YFR016C

PTM databases

iPTMnetiP43597

Proteomic databases

MaxQBiP43597
PaxDbiP43597
PRIDEiP43597

Genome annotation databases

EnsemblFungiiYFR016C_mRNA; YFR016C; YFR016C
GeneIDi850570
KEGGisce:YFR016C

Organism-specific databases

EuPathDBiFungiDB:YFR016C
SGDiS000001912 YFR016C

Phylogenomic databases

InParanoidiP43597
OMAiDQHEKKE

Enzyme and pathway databases

BioCyciYEAST:G3O-30468-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P43597

Family and domain databases

Gene3Di3.40.30.10, 1 hit
InterProiView protein in InterPro
IPR002109 Glutaredoxin
IPR036249 Thioredoxin-like_sf
SUPFAMiSSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS51354 GLUTAREDOXIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYFI6_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P43597
Secondary accession number(s): D6VTP7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 13, 2019
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names
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