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UniProtKB - P43548 (AGP3_YEAST)
Protein
General amino acid permease AGP3
Gene
AGP3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
General amino acid permease with broad substrate specificity.
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: SGD
GO - Biological processi
- amino acid transmembrane transport Source: GO_Central
- amino acid transport Source: SGD
- transmembrane transport Source: SGD
Keywordsi
Biological process | Amino-acid transport, Transport |
Enzyme and pathway databases
SABIO-RKi | P43548 |
Protein family/group databases
TCDBi | 2.A.3.10.14, the amino acid-polyamine-organocation (apc) family |
Names & Taxonomyi
Protein namesi | Recommended name: General amino acid permease AGP3 |
Gene namesi | Name:AGP3 Ordered Locus Names:YFL055W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000001839, AGP3 |
VEuPathDBi | FungiDB:YFL055W |
Subcellular locationi
Other locations
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 57 | CytoplasmicSequence analysisAdd BLAST | 57 | |
Transmembranei | 58 – 78 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 79 – 81 | ExtracellularSequence analysis | 3 | |
Transmembranei | 82 – 102 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 103 – 126 | CytoplasmicSequence analysisAdd BLAST | 24 | |
Transmembranei | 127 – 147 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 148 – 168 | ExtracellularSequence analysisAdd BLAST | 21 | |
Transmembranei | 169 – 189 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 190 – 193 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 194 – 214 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 215 – 241 | ExtracellularSequence analysisAdd BLAST | 27 | |
Transmembranei | 242 – 262 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 263 – 280 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 281 – 301 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 302 – 324 | ExtracellularSequence analysisAdd BLAST | 23 | |
Transmembranei | 325 – 345 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 346 – 375 | CytoplasmicSequence analysisAdd BLAST | 30 | |
Transmembranei | 376 – 396 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 397 – 402 | ExtracellularSequence analysis | 6 | |
Transmembranei | 403 – 423 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 424 – 446 | CytoplasmicSequence analysisAdd BLAST | 23 | |
Transmembranei | 447 – 467 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 468 – 480 | ExtracellularSequence analysisAdd BLAST | 13 | |
Transmembranei | 481 – 501 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 502 – 558 | CytoplasmicSequence analysisAdd BLAST | 57 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054144 | 1 – 558 | General amino acid permease AGP3Add BLAST | 558 |
Proteomic databases
PaxDbi | P43548 |
PTM databases
iPTMneti | P43548 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31092, 52 interactors |
DIPi | DIP-4160N |
IntActi | P43548, 3 interactors |
MINTi | P43548 |
STRINGi | 4932.YFL055W |
Miscellaneous databases
RNActi | P43548, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_2_1 |
InParanoidi | P43548 |
OMAi | PMTIAIQ |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P43548-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVLNLKRET VDIEETAKKD IKPYFASNVE AVDIDEDPDV SRYDPQTGVK
60 70 80 90 100
RALKNRHISL LALGGVIGPG CLVGAGNALN KGGPLALLLG FSIIGIIAFS
110 120 130 140 150
VMESIGEMIT LYPSGGGFTT LARRFHSDAL PAVCGYAYVV VFFAVLANEY
160 170 180 190 200
NTLSSILQFW GPQVPLYGYI LIFWFAFEIF QLVGVGLFGE TEYWLAWLKI
210 220 230 240 250
VGLVAYYIFS IVYISGDIRN RPAFGFHYWN SPGALSHGFK GIAIVFVFCS
260 270 280 290 300
TFYSGTESVA LAATESKNPG KAVPLAVRQT LWRILVVYIG IAVFYGATVP
310 320 330 340 350
FDDPNLSAST KVLKSPIAIA ISRAGWAGGA HLVNAFILIT CISAINGSLY
360 370 380 390 400
IGSRTLTHLA HEGLAPKILA WTDRRGVPIP AITVFNALGL ISLMNVSVGA
410 420 430 440 450
ANAYSYIVNL SGVGVFIVWG VISYTHLRIR KAWVAQGRSI EELPYEALFY
460 470 480 490 500
PWTPVLSLAA NIFLALIQGW SYFVPFDAGN FVDAYILLPV GILLYIGICV
510 520 530 540 550
FKSNHFRTVD LRSINLDEGR RKDMEADLSD QESSLASSET MKDYKSATFF
RYLSNIFT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D50617 Genomic DNA Translation: BAA09186.1 BK006940 Genomic DNA Translation: DAA12385.1 |
PIRi | S56200 |
RefSeqi | NP_116600.1, NM_001179912.1 |
Genome annotation databases
EnsemblFungii | YFL055W_mRNA; YFL055W; YFL055W |
GeneIDi | 850489 |
KEGGi | sce:YFL055W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D50617 Genomic DNA Translation: BAA09186.1 BK006940 Genomic DNA Translation: DAA12385.1 |
PIRi | S56200 |
RefSeqi | NP_116600.1, NM_001179912.1 |
3D structure databases
SMRi | P43548 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 31092, 52 interactors |
DIPi | DIP-4160N |
IntActi | P43548, 3 interactors |
MINTi | P43548 |
STRINGi | 4932.YFL055W |
Protein family/group databases
TCDBi | 2.A.3.10.14, the amino acid-polyamine-organocation (apc) family |
PTM databases
iPTMneti | P43548 |
Proteomic databases
PaxDbi | P43548 |
Genome annotation databases
EnsemblFungii | YFL055W_mRNA; YFL055W; YFL055W |
GeneIDi | 850489 |
KEGGi | sce:YFL055W |
Organism-specific databases
SGDi | S000001839, AGP3 |
VEuPathDBi | FungiDB:YFL055W |
Phylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_2_1 |
InParanoidi | P43548 |
OMAi | PMTIAIQ |
Enzyme and pathway databases
SABIO-RKi | P43548 |
Miscellaneous databases
PROi | PR:P43548 |
RNActi | P43548, protein |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AGP3_YEAST | |
Accessioni | P43548Primary (citable) accession number: P43548 Secondary accession number(s): D6VTH5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | February 23, 2022 | |
This is version 166 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VI
Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names - SIMILARITY comments
Index of protein domains and families