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Protein

Inner membrane transport protein YnfM

Gene

ynfM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:B1596-MONOMER

Protein family/group databases

TCDBi2.A.1.36.1 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport protein YnfM
Gene namesi
Name:ynfM
Synonyms:yzyC
Ordered Locus Names:b1596, JW1588
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12951 ynfM

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 38PeriplasmicSequence analysisAdd BLAST38
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Topological domaini60 – 73CytoplasmicSequence analysisAdd BLAST14
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95 – 101PeriplasmicSequence analysis7
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Topological domaini123 – 125CytoplasmicSequence analysis3
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Topological domaini147 – 152PeriplasmicSequence analysis6
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Topological domaini174 – 190CytoplasmicSequence analysisAdd BLAST17
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Topological domaini212 – 241PeriplasmicSequence analysisAdd BLAST30
Transmembranei242 – 262HelicalSequence analysisAdd BLAST21
Topological domaini263 – 264CytoplasmicSequence analysis2
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Topological domaini286 – 315PeriplasmicSequence analysisAdd BLAST30
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Topological domaini337 – 364CytoplasmicSequence analysisAdd BLAST28
Transmembranei365 – 385HelicalSequence analysisAdd BLAST21
Topological domaini386 – 387PeriplasmicSequence analysis2
Transmembranei388 – 408HelicalSequence analysisAdd BLAST21
Topological domaini409 – 417CytoplasmicSequence analysis9

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001734111 – 417Inner membrane transport protein YnfMAdd BLAST417

Proteomic databases

PaxDbiP43531
PRIDEiP43531

Interactioni

Protein-protein interaction databases

BioGridi4259121, 157 interactors
STRINGi316385.ECDH10B_1729

Structurei

3D structure databases

ProteinModelPortaliP43531
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D94 Bacteria
ENOG410XP8J LUCA
HOGENOMiHOG000217197
InParanoidiP43531
KOiK08224
OMAiLYCVQPM
PhylomeDBiP43531

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit

Sequencei

Sequence statusi: Complete.

P43531-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRTTTVDGA PASDTDKQSI SQPNQFIKRG TPQFMRVTLA LFSAGLATFA
60 70 80 90 100
LLYCVQPILP VLSQEFGLTP ANSSISLSIS TAMLAIGLLF TGPLSDAIGR
110 120 130 140 150
KPVMVTALLL ASICTLLSTM MTSWHGILIM RALIGLSLSG VAAVGMTYLS
160 170 180 190 200
EEIHPSFVAF SMGLYISGNS IGGMSGRLIS GVFTDFFNWR IALAAIGCFA
210 220 230 240 250
LASALMFWKI LPESRHFRPT SLRPKTLFIN FRLHWRDRGL PLLFAEGFLL
260 270 280 290 300
MGSFVTLFNY IGYRLMLSPW HVSQAVVGLL SLAYLTGTWS SPKAGTMTTR
310 320 330 340 350
YGRGPVMLFS TGVMLFGLLM TLFSSLWLIF AGMLLFSAGF FAAHSVASSW
360 370 380 390 400
IGPRAKRAKG QASSLYLFSY YLGSSIAGTL GGVFWHNYGW NGVGAFIALM
410
LVIALLVGTR LHRRLHA
Length:417
Mass (Da):45,258
Last modified:November 1, 1997 - v2
Checksum:i78862FD89AD1987B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74668.1
AP009048 Genomic DNA Translation: BAA15330.1
AF405541 Genomic DNA No translation available.
PIRiF64915
RefSeqiNP_416113.1, NC_000913.3
WP_000091840.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74668; AAC74668; b1596
BAA15330; BAA15330; BAA15330
GeneIDi946138
KEGGiecj:JW1588
eco:b1596
PATRICifig|1411691.4.peg.666

Similar proteinsi

Entry informationi

Entry nameiYNFM_ECOLI
AccessioniPrimary (citable) accession number: P43531
Secondary accession number(s): P76886, P77705
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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