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Protein

Melanoma-associated antigen 3

Gene

MAGEA3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.1 Publication

Caution

In vitro experiments by PubMed:17942928 measuring cell viability in melanoma cell lines used siRNA specific for MAGEA3 and MAGEA6.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • caspase binding Source: ParkinsonsUK-UCL

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTumor antigen
Biological processUbl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Melanoma-associated antigen 3
Alternative name(s):
Antigen MZ2-D
Cancer/testis antigen 1.3
Short name:
CT1.3
MAGE-3 antigen
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAGEA3
Synonyms:MAGE3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000221867.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6801 MAGEA3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300174 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P43357

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi170D → A: Abolishes HLA-A1 binding. 1 Publication1
Mutagenesisi176Y → A: Abolishes HLA-A1 binding. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
4102

Open Targets

More...
OpenTargetsi
ENSG00000221867

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30547

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MAGEA3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
1170857

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001567031 – 314Melanoma-associated antigen 3Add BLAST314

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P43357

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P43357

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P43357

PeptideAtlas

More...
PeptideAtlasi
P43357

PRoteomics IDEntifications database

More...
PRIDEi
P43357

ProteomicsDB human proteome resource

More...
ProteomicsDBi
55619

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P43357

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P43357

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never expressed in kidney tumors, Leukemias and lymphomas.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000221867 Expressed in 21 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_MAGEA3

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P43357 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P43357 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TRIM28.3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
TRIM28Q132633EBI-5651459,EBI-78139

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110276, 5 interactors

Database of interacting proteins

More...
DIPi
DIP-44886N

Protein interaction database and analysis system

More...
IntActi
P43357, 15 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000359301

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1314
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P43357

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P43357

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P43357

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini109 – 308MAGEPROSITE-ProRule annotationAdd BLAST200

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi40 – 43Poly-Ser4

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4562 Eukaryota
ENOG4111S70 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164672

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231161

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG006315

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P43357

Identification of Orthologs from Complete Genome Data

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OMAi
IAREGDC

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0TJ0

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P43357

TreeFam database of animal gene trees

More...
TreeFami
TF328505

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR037445 MAGE
IPR021072 MAGE_N
IPR030097 MAGEA3/MAGEA6
IPR002190 MHD_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11736 PTHR11736, 1 hit
PTHR11736:SF60 PTHR11736:SF60, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01454 MAGE, 1 hit
PF12440 MAGE_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01373 MAGE, 1 hit
SM01392 MAGE_N, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50838 MAGE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P43357-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQEAAS SSSTLVEVTL
60 70 80 90 100
GEVPAAESPD PPQSPQGASS LPTTMNYPLW SQSYEDSSNQ EEEGPSTFPD
110 120 130 140 150
LESEFQAALS RKVAELVHFL LLKYRAREPV TKAEMLGSVV GNWQYFFPVI
160 170 180 190 200
FSKASSSLQL VFGIELMEVD PIGHLYIFAT CLGLSYDGLL GDNQIMPKAG
210 220 230 240 250
LLIIVLAIIA REGDCAPEEK IWEELSVLEV FEGREDSILG DPKKLLTQHF
260 270 280 290 300
VQENYLEYRQ VPGSDPACYE FLWGPRALVE TSYVKVLHHM VKISGGPHIS
310
YPPLHEWVLR EGEE
Length:314
Mass (Da):34,747
Last modified:November 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3F5EB13D1C9946A1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EMU0E7EMU0_HUMAN
Melanoma-associated antigen 3
MAGEA3
198Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U03735 Genomic DNA Translation: AAA17446.1
U82671 Genomic DNA No translation available.
CR541767 mRNA Translation: CAG46566.1
CR541774 mRNA Translation: CAG46573.1
AK292384 mRNA Translation: BAF85073.1
BC000340 mRNA Translation: AAH00340.1
BC005963 mRNA Translation: AAH05963.1
BC011744 mRNA Translation: AAH11744.1
BC016803 mRNA Translation: AAH16803.1
BC017389 mRNA Translation: AAH17389.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS76045.1

Protein sequence database of the Protein Information Resource

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PIRi
JC2361

NCBI Reference Sequences

More...
RefSeqi
NP_005353.1, NM_005362.3
XP_005274733.1, XM_005274676.3
XP_006724881.1, XM_006724818.2
XP_011529462.1, XM_011531160.2
XP_011529463.1, XM_011531161.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.417816

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000370278; ENSP00000359301; ENSG00000221867
ENST00000598245; ENSP00000473093; ENSG00000221867

Database of genes from NCBI RefSeq genomes

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GeneIDi
4102

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:4102

UCSC genome browser

More...
UCSCi
uc033faf.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03735 Genomic DNA Translation: AAA17446.1
U82671 Genomic DNA No translation available.
CR541767 mRNA Translation: CAG46566.1
CR541774 mRNA Translation: CAG46573.1
AK292384 mRNA Translation: BAF85073.1
BC000340 mRNA Translation: AAH00340.1
BC005963 mRNA Translation: AAH05963.1
BC011744 mRNA Translation: AAH11744.1
BC016803 mRNA Translation: AAH16803.1
BC017389 mRNA Translation: AAH17389.1
CCDSiCCDS76045.1
PIRiJC2361
RefSeqiNP_005353.1, NM_005362.3
XP_005274733.1, XM_005274676.3
XP_006724881.1, XM_006724818.2
XP_011529462.1, XM_011531160.2
XP_011529463.1, XM_011531161.2
UniGeneiHs.417816

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QEWX-ray2.20C271-279[»]
4V0PX-ray2.07A104-314[»]
5BRZX-ray2.62C168-176[»]
ProteinModelPortaliP43357
SMRiP43357
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110276, 5 interactors
DIPiDIP-44886N
IntActiP43357, 15 interactors
STRINGi9606.ENSP00000359301

PTM databases

iPTMnetiP43357
PhosphoSitePlusiP43357

Polymorphism and mutation databases

BioMutaiMAGEA3
DMDMi1170857

Proteomic databases

EPDiP43357
MaxQBiP43357
PaxDbiP43357
PeptideAtlasiP43357
PRIDEiP43357
ProteomicsDBi55619

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4102
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370278; ENSP00000359301; ENSG00000221867
ENST00000598245; ENSP00000473093; ENSG00000221867
GeneIDi4102
KEGGihsa:4102
UCSCiuc033faf.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4102
DisGeNETi4102
EuPathDBiHostDB:ENSG00000221867.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MAGEA3
HGNCiHGNC:6801 MAGEA3
MIMi300174 gene
neXtProtiNX_P43357
OpenTargetsiENSG00000221867
PharmGKBiPA30547

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4562 Eukaryota
ENOG4111S70 LUCA
GeneTreeiENSGT00940000164672
HOGENOMiHOG000231161
HOVERGENiHBG006315
InParanoidiP43357
OMAiIAREGDC
OrthoDBiEOG091G0TJ0
PhylomeDBiP43357
TreeFamiTF328505

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MAGEA3 human
EvolutionaryTraceiP43357

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
MAGEA3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
4102

Protein Ontology

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PROi
PR:P43357

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000221867 Expressed in 21 organ(s), highest expression level in testis
CleanExiHS_MAGEA3
ExpressionAtlasiP43357 baseline and differential
GenevisibleiP43357 HS

Family and domain databases

InterProiView protein in InterPro
IPR037445 MAGE
IPR021072 MAGE_N
IPR030097 MAGEA3/MAGEA6
IPR002190 MHD_dom
PANTHERiPTHR11736 PTHR11736, 1 hit
PTHR11736:SF60 PTHR11736:SF60, 1 hit
PfamiView protein in Pfam
PF01454 MAGE, 1 hit
PF12440 MAGE_N, 1 hit
SMARTiView protein in SMART
SM01373 MAGE, 1 hit
SM01392 MAGE_N, 1 hit
PROSITEiView protein in PROSITE
PS50838 MAGE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAGA3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P43357
Secondary accession number(s): Q6FHI6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: December 5, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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