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Protein

Uncharacterized Nudix hydrolase NudL

Gene

nudL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.UniRule annotation

Cofactori

Mn2+UniRule annotation, Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi83Magnesium or manganeseUniRule annotation1
Metal bindingi87Magnesium or manganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG12693-MONOMER
MetaCyc:EG12693-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized Nudix hydrolase NudLUniRule annotation (EC:3.6.1.-UniRule annotation)
Gene namesi
Name:nudLUniRule annotation
Synonyms:yeaB
Ordered Locus Names:b1813, JW1802
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12693 nudL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000571451 – 192Uncharacterized Nudix hydrolase NudLAdd BLAST192

Proteomic databases

PaxDbiP43337
PRIDEiP43337

Interactioni

Protein-protein interaction databases

BioGridi4263367, 35 interactors
DIPiDIP-11783N
IntActiP43337, 5 interactors
STRINGi316385.ECDH10B_1951

Structurei

3D structure databases

ProteinModelPortaliP43337
SMRiP43337
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 160Nudix hydrolaseUniRule annotationAdd BLAST132

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi67 – 89Nudix boxAdd BLAST23

Sequence similaritiesi

Belongs to the Nudix hydrolase family. PCD1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105P8F Bacteria
COG0494 LUCA
HOGENOMiHOG000250455
InParanoidiP43337
OMAiHPGQMSF
PhylomeDBiP43337

Family and domain databases

HAMAPiMF_01592 Nudix_NudL, 1 hit
InterProiView protein in InterPro
IPR015797 NUDIX_hydrolase-like_dom_sf
IPR000086 NUDIX_hydrolase_dom
IPR000059 NUDIX_hydrolase_NudL_CS
IPR023735 Nudix_NudL
PfamiView protein in Pfam
PF00293 NUDIX, 1 hit
SUPFAMiSSF55811 SSF55811, 1 hit
PROSITEiView protein in PROSITE
PS51462 NUDIX, 1 hit
PS01293 NUDIX_COA, 1 hit

Sequencei

Sequence statusi: Complete.

P43337-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYRSLTLDD FLSRFQLLRP QINRETLNHR QAAVLIPIVR RPQPGLLLTQ
60 70 80 90 100
RSIHLRKHAG QVAFPGGAVD DTDASAIAAA LREAEEEVAI PPSAVEVIGV
110 120 130 140 150
LPPVDSVTGY QVTPVVGIIP PDLPYRASED EVSAVFEMPL AQALHLGRYH
160 170 180 190
PLDIYRRGDS HRVWLSWYEQ YFVWGMTAGI IRELALQIGV KP
Length:192
Mass (Da):21,436
Last modified:November 1, 1995 - v1
Checksum:iA4CAEC50B1767ECF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74883.1
AP009048 Genomic DNA Translation: BAA15620.1
K02673 Genomic DNA No translation available.
M28695 Genomic DNA No translation available.
PIRiE64942
RefSeqiNP_416327.1, NC_000913.3
WP_000456715.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74883; AAC74883; b1813
BAA15620; BAA15620; BAA15620
GeneIDi946330
KEGGiecj:JW1802
eco:b1813
PATRICifig|1411691.4.peg.439

Similar proteinsi

Entry informationi

Entry nameiNUDL_ECOLI
AccessioniPrimary (citable) accession number: P43337
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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