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Protein

Probable cysteine protease RD19B

Gene

RD19B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable thiol protease.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei156PROSITE-ProRule annotation1
Active sitei299PROSITE-ProRule annotation1
Active sitei326PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease

Enzyme and pathway databases

ReactomeiR-ATH-2132295 MHC class II antigen presentation

Protein family/group databases

MEROPSiC01.A04

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine protease RD19BCurated (EC:3.4.22.-)
Alternative name(s):
RD19-like protein 11 Publication
Thiol protease A14941 Publication
Gene namesi
Name:RD19BCurated
Synonyms:RDL11 Publication
Ordered Locus Names:At2g21430
ORF Names:F3K23.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G21430
TAIRilocus:2050145 AT2G21430

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
PropeptideiPRO_000002645325 – 131Activation peptideCuratedAdd BLAST107
ChainiPRO_0000026454132 – 361Probable cysteine protease RD19BAdd BLAST230

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi153 ↔ 203By similarity
Disulfide bondi187 ↔ 237By similarity
Glycosylationi250N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi293 ↔ 347By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiP43295

Expressioni

Inductioni

By wilting and abscisic acid (ABA) (PubMed:8018874). Induced by drought stress (PubMed:12102506).2 Publications

Gene expression databases

ExpressionAtlasiP43295 baseline and differential
GenevisibleiP43295 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G21430.1

Structurei

3D structure databases

ProteinModelPortaliP43295
SMRiP43295
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1542 Eukaryota
COG4870 LUCA
HOGENOMiHOG000230774
InParanoidiP43295
KOiK01373
OMAiAMRHQKM
OrthoDBiEOG09360CFD
PhylomeDBiP43295

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR025661 Pept_asp_AS
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR013201 Prot_inhib_I29
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF08246 Inhibitor_I29, 1 hit
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00848 Inhibitor_I29, 1 hit
SM00645 Pept_C1, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00640 THIOL_PROTEASE_ASN, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43295-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYHLRVLFS VSLIFVFVSV SVCGDEDVLI RQVVDETEPK VLSSEDHFTL
60 70 80 90 100
FKKKFGKVYG SIEEHYYRFS VFKANLLRAM RHQKMDPSAR HGVTQFSDLT
110 120 130 140 150
RSEFRRKHLG VKGGFKLPKD ANQAPILPTQ NLPEEFDWRD RGAVTPVKNQ
160 170 180 190 200
GSCGSCWSFS TTGALEGAHF LATGKLVSLS EQQLVDCDHE CDPEEEGSCD
210 220 230 240 250
SGCNGGLMNS AFEYTLKTGG LMREKDYPYT GTDGGSCKLD RSKIVASVSN
260 270 280 290 300
FSVVSINEDQ IAANLIKNGP LAVAINAAYM QTYIGGVSCP YICSRRLNHG
310 320 330 340 350
VLLVGYGSAG FSQARLKEKP YWIIKNSWGE SWGENGFYKI CKGRNICGVD
360
SLVSTVAATT S
Length:361
Mass (Da):39,819
Last modified:December 8, 2000 - v2
Checksum:iD09A2CE5654642DD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti49T → A in CAA52403 (PubMed:8018874).Curated1
Sequence conflicti206G → R in BAD43619 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006841 Genomic DNA Translation: AAD23687.1
CP002685 Genomic DNA Translation: AEC07177.1
AK175856 mRNA Translation: BAD43619.1
BT029231 mRNA Translation: ABJ98563.1
X74359 mRNA Translation: CAA52403.1
PIRiB84601
RefSeqiNP_565512.1, NM_127715.4
UniGeneiAt.14069

Genome annotation databases

EnsemblPlantsiAT2G21430.1; AT2G21430.1; AT2G21430
GeneIDi816682
GrameneiAT2G21430.1; AT2G21430.1; AT2G21430
KEGGiath:AT2G21430

Similar proteinsi

Entry informationi

Entry nameiRD19B_ARATH
AccessioniPrimary (citable) accession number: P43295
Secondary accession number(s): Q058I7, Q680L1, Q9SJT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 8, 2000
Last modified: June 20, 2018
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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