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Protein

Protein SOX-15

Gene

Sox15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi47 – 115HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SOX-15
Gene namesi
Name:Sox15
Synonyms:Sox-15
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98363 Sox15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000487631 – 231Protein SOX-15Add BLAST231

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei35PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP43267
PRIDEiP43267

PTM databases

PhosphoSitePlusiP43267

Expressioni

Gene expression databases

BgeeiENSMUSG00000041287 Expressed in 133 organ(s), highest expression level in testis
CleanExiMM_SOX15
ExpressionAtlasiP43267 baseline and differential
GenevisibleiP43267 MM

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Fhl3Q9R0597EBI-7332587,EBI-7332617

GO - Molecular functioni

Protein-protein interaction databases

BioGridi203402, 5 interactors
IntActiP43267, 1 interactor
MINTiP43267
STRINGi10090.ENSMUSP00000048524

Structurei

3D structure databases

ProteinModelPortaliP43267
SMRiP43267
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0527 Eukaryota
ENOG410XT0K LUCA
GeneTreeiENSGT00760000118988
HOVERGENiHBG055512
InParanoidiP43267
KOiK09271
OMAiYGSSHCK
OrthoDBiEOG091G0M3O
PhylomeDBiP43267
TreeFamiTF351735

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR031269 SOX15
PANTHERiPTHR10270:SF45 PTHR10270:SF45, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

P43267-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALTSSSQAE TWSLHPRAST ASLPLGPQEQ EAGGSPGASG GLPLEKVKRP
60 70 80 90 100
MNAFMVWSSV QRRQMAQQNP KMHNSEISKR LGAQWKLLGD EEKRPFVEEA
110 120 130 140 150
KRLRARHLRD YPDYKYRPRR KSKNSSTGSV PFSQEGGGLA CGGSHWGPGY
160 170 180 190 200
TTTQGSRGFG YQPPNYSTAY LPGSYTSSHC RPEAPLPCTF PQSDPRLQGE
210 220 230
LRPSFSPYLS PDSSTPYNTS LAGAPMPVTH L
Length:231
Mass (Da):25,311
Last modified:December 8, 2000 - v3
Checksum:iFCFE87C3BB458645
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti71K → E in BAA28604 (PubMed:10524236).Curated1
Sequence conflicti97V → M in CAB37848 (PubMed:8479922).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti135E → G in strain: various strains. 1
Natural varianti224A → S in strain: various strains. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014474 Genomic DNA Translation: BAA28604.1
AF182945 mRNA Translation: AAF72108.1
AB039214 Genomic DNA Translation: BAB68738.1
AB039215 Genomic DNA Translation: BAB68739.1
AB039216 Genomic DNA Translation: BAB68740.1
AB039217 Genomic DNA Translation: BAB68741.1
AB039218 Genomic DNA Translation: BAB68742.1
AB039219 Genomic DNA Translation: BAB68743.1
AB039220 Genomic DNA Translation: BAB68744.1
AB039221 Genomic DNA Translation: BAB68745.1
AB039222 Genomic DNA Translation: BAB68746.1
U70443 mRNA Translation: AAC52861.1
X70909 Genomic DNA Translation: CAB37848.1
X98369 mRNA Translation: CAA67015.1
CCDSiCCDS24902.1
PIRiS33715
RefSeqiNP_033261.1, NM_009235.2
UniGeneiMm.347499

Genome annotation databases

EnsembliENSMUST00000047373; ENSMUSP00000048524; ENSMUSG00000041287
GeneIDi20670
KEGGimmu:20670
UCSCiuc007jqu.2 mouse

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014474 Genomic DNA Translation: BAA28604.1
AF182945 mRNA Translation: AAF72108.1
AB039214 Genomic DNA Translation: BAB68738.1
AB039215 Genomic DNA Translation: BAB68739.1
AB039216 Genomic DNA Translation: BAB68740.1
AB039217 Genomic DNA Translation: BAB68741.1
AB039218 Genomic DNA Translation: BAB68742.1
AB039219 Genomic DNA Translation: BAB68743.1
AB039220 Genomic DNA Translation: BAB68744.1
AB039221 Genomic DNA Translation: BAB68745.1
AB039222 Genomic DNA Translation: BAB68746.1
U70443 mRNA Translation: AAC52861.1
X70909 Genomic DNA Translation: CAB37848.1
X98369 mRNA Translation: CAA67015.1
CCDSiCCDS24902.1
PIRiS33715
RefSeqiNP_033261.1, NM_009235.2
UniGeneiMm.347499

3D structure databases

ProteinModelPortaliP43267
SMRiP43267
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi203402, 5 interactors
IntActiP43267, 1 interactor
MINTiP43267
STRINGi10090.ENSMUSP00000048524

PTM databases

PhosphoSitePlusiP43267

Proteomic databases

PaxDbiP43267
PRIDEiP43267

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047373; ENSMUSP00000048524; ENSMUSG00000041287
GeneIDi20670
KEGGimmu:20670
UCSCiuc007jqu.2 mouse

Organism-specific databases

CTDi6665
MGIiMGI:98363 Sox15

Phylogenomic databases

eggNOGiKOG0527 Eukaryota
ENOG410XT0K LUCA
GeneTreeiENSGT00760000118988
HOVERGENiHBG055512
InParanoidiP43267
KOiK09271
OMAiYGSSHCK
OrthoDBiEOG091G0M3O
PhylomeDBiP43267
TreeFamiTF351735

Miscellaneous databases

PROiPR:P43267
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041287 Expressed in 133 organ(s), highest expression level in testis
CleanExiMM_SOX15
ExpressionAtlasiP43267 baseline and differential
GenevisibleiP43267 MM

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR031269 SOX15
PANTHERiPTHR10270:SF45 PTHR10270:SF45, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSOX15_MOUSE
AccessioniPrimary (citable) accession number: P43267
Secondary accession number(s): O70204
, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 8, 2000
Last modified: November 7, 2018
This is version 141 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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