UniProtKB - P43213 (MPAP1_PHLPR)
Protein
Pollen allergen Phl p 1
Gene
PHLPI
Organism
Phleum pratense (Common timothy)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Pollen allergen Phl p 1Alternative name(s): Allergen Phl p I Allergen: Phl p 1 |
Gene namesi | Name:PHLPI |
Organismi | Phleum pratense (Common timothy) |
Taxonomic identifieri | 15957 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Pooideae › Poodae › Poeae › Poeae Chloroplast Group 2 (Poeae type) › Poinae › Phleum |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPathology & Biotechi
Allergenic propertiesi
Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.1 Publication
Keywords - Diseasei
AllergenProtein family/group databases
Allergomei | 549, Phl p 1 551, Phl p 1.0102 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_0000008722 | 24 – 263 | Pollen allergen Phl p 1Add BLAST | 240 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 32 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Disulfide bondi | 64 ↔ 92 | |||
Disulfide bondi | 95 ↔ 162 | |||
Disulfide bondi | 100 ↔ 106 |
Keywords - PTMi
Disulfide bond, GlycoproteinPTM databases
iPTMneti | P43213 |
Interactioni
Subunit structurei
Homodimer.
1 PublicationStructurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P43213 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P43213 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 61 – 167 | Expansin-like EG45PROSITE-ProRule annotationAdd BLAST | 107 | |
Domaini | 181 – 262 | Expansin-like CBDPROSITE-ProRule annotationAdd BLAST | 82 |
Sequence similaritiesi
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 2.40.40.10, 1 hit 2.60.40.760, 1 hit |
InterProi | View protein in InterPro IPR007118, Expan_Lol_pI IPR007112, Expansin/allergen_DPBB_dom IPR007117, Expansin_CBD IPR036749, Expansin_CBD_sf IPR005795, LolPI IPR009009, RlpA-like_DPBB IPR036908, RlpA-like_sf |
Pfami | View protein in Pfam PF03330, DPBB_1, 1 hit PF01357, Expansin_C, 1 hit |
PRINTSi | PR01225, EXPANSNFAMLY PR00829, LOLP1ALLERGN |
SMARTi | View protein in SMART SM00837, DPBB_1, 1 hit |
SUPFAMi | SSF49590, SSF49590, 1 hit SSF50685, SSF50685, 1 hit |
PROSITEi | View protein in PROSITE PS50843, EXPANSIN_CBD, 1 hit PS50842, EXPANSIN_EG45, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P43213-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSSSVLLV VVLFAVFLGS AYGIPKVPPG PNITATYGDK WLDAKSTWYG
60 70 80 90 100
KPTGAGPKDN GGACGYKDVD KPPFSGMTGC GNTPIFKSGR GCGSCFEIKC
110 120 130 140 150
TKPEACSGEP VVVHITDDNE EPIAPYHFDL SGHAFGAMAK KGDEQKLRSA
160 170 180 190 200
GELELQFRRV KCKYPEGTKV TFHVEKGSNP NYLALLVKYV NGDGDVVAVD
210 220 230 240 250
IKEKGKDKWI ELKESWGAIW RIDTPDKLTG PFTVRYTTEG GTKTEAEDVI
260
PEGWKADTSY ESK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X78813 mRNA Translation: CAA55390.1 |
PIRi | S44182 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X78813 mRNA Translation: CAA55390.1 |
PIRi | S44182 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1N10 | X-ray | 2.90 | A/B | 23-263 | [»] | |
SMRi | P43213 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein family/group databases
Allergomei | 549, Phl p 1 551, Phl p 1.0102 |
PTM databases
iPTMneti | P43213 |
Protocols and materials databases
ABCDi | P43213, 11 sequenced antibodies |
Miscellaneous databases
EvolutionaryTracei | P43213 |
Family and domain databases
Gene3Di | 2.40.40.10, 1 hit 2.60.40.760, 1 hit |
InterProi | View protein in InterPro IPR007118, Expan_Lol_pI IPR007112, Expansin/allergen_DPBB_dom IPR007117, Expansin_CBD IPR036749, Expansin_CBD_sf IPR005795, LolPI IPR009009, RlpA-like_DPBB IPR036908, RlpA-like_sf |
Pfami | View protein in Pfam PF03330, DPBB_1, 1 hit PF01357, Expansin_C, 1 hit |
PRINTSi | PR01225, EXPANSNFAMLY PR00829, LOLP1ALLERGN |
SMARTi | View protein in SMART SM00837, DPBB_1, 1 hit |
SUPFAMi | SSF49590, SSF49590, 1 hit SSF50685, SSF50685, 1 hit |
PROSITEi | View protein in PROSITE PS50843, EXPANSIN_CBD, 1 hit PS50842, EXPANSIN_EG45, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MPAP1_PHLPR | |
Accessioni | P43213Primary (citable) accession number: P43213 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 113 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Allergens
Nomenclature of allergens and list of entries