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Protein

D-arabinitol 2-dehydrogenase [ribulose-forming]

Gene

ARD1

Organism
Candida albicans (strain WO-1) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-arabinitol + NAD+ = D-ribulose + NADH.

Pathwayi: D-arabinitol metabolism

This protein is involved in the pathway D-arabinitol metabolism, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway D-arabinitol metabolism and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei169SubstrateBy similarity1
Active sitei184Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 47NADBy similarityAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

UniPathwayiUPA00380

Names & Taxonomyi

Protein namesi
Recommended name:
D-arabinitol 2-dehydrogenase [ribulose-forming] (EC:1.1.1.250)
Short name:
ARDH
Gene namesi
Name:ARD1
Synonyms:ARDH
OrganismiCandida albicans (strain WO-1) (Yeast)
Taxonomic identifieri294748 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000001429 Componenti: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000545171 – 281D-arabinitol 2-dehydrogenase [ribulose-forming]Add BLAST281

Proteomic databases

PRIDEiP43066

Structurei

3D structure databases

ProteinModelPortaliP43066
SMRiP43066
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OrthoDBiEOG092C3TSH

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

P43066-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSAYWSYDN IVPSFRLDGK LVILTGGSGG LAAVVSRALL AKGADVALVD
60 70 80 90 100
MNLERTQQAA RDVLQWGEEQ MKGKYESPIG QVSAWSCNIG DAEAVDLTFK
110 120 130 140 150
AINEHHGKIS SVLVNTAGYA ENFPAEEYPA KNAENLMKVN GLGSFYVSQA
160 170 180 190 200
FARPLIQNNM TGSIILIGSM SGTIVNDPQP QCMYNMSKAG VIHLARSLAC
210 220 230 240 250
EWAKYNIRVN TLSPGYILTP LTRNVISGHT EMKTEWESKI PMKRMAEPKE
260 270 280
FVGSILYLAS ESASSYTTGH NLVVDGGYEC W
Length:281
Mass (Da):30,643
Last modified:November 1, 1995 - v1
Checksum:iB302A6411691F892
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L16227 Genomic DNA Translation: AAC37430.1
CM000312 Genomic DNA No translation available.

Similar proteinsi

Entry informationi

Entry nameiARDH_CANAW
AccessioniPrimary (citable) accession number: P43066
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 25, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome