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UniProtKB - P42954 (TAGH_BACSU)
Protein
Teichoic acids export ATP-binding protein TagH
Gene
tagH
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system.
UniRule annotation1 PublicationCatalytic activityi
- ATP + H(2)O + teichoic acid(Side 1) = ADP + phosphate + teichoic acid(Side 2).UniRule annotation EC:7.5.2.4
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 56 – 63 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ABC-type teichoic acid transporter activity Source: UniProtKB-EC
- ATP binding Source: UniProtKB-KW
Keywordsi
Molecular function | Translocase |
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU35700-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.104.1, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Teichoic acids export ATP-binding protein TagHUniRule annotation (EC:7.5.2.4UniRule annotation)Alternative name(s): Teichoic acid-transporting ATPase |
Gene namesi | Name:tagHUniRule annotation Ordered Locus Names:BSU35700 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000092988 | 1 – 527 | Teichoic acids export ATP-binding protein TagHAdd BLAST | 527 |
Proteomic databases
jPOSTi | P42954 |
PaxDbi | P42954 |
PRIDEi | P42954 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (TagH) and two transmembrane proteins (TagG).
UniRule annotationBinary interactionsi
Protein-protein interaction databases
IntActi | P42954, 7 interactors |
STRINGi | 224308.BSU35700 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P42954 |
SMRi | P42954 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 242 | ABC transporterUniRule annotationAdd BLAST | 238 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 243 – 527 | UnknownAdd BLAST | 285 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family. [View classification]UniRule annotation
Phylogenomic databases
eggNOGi | COG1134, Bacteria |
InParanoidi | P42954 |
OMAi | CVDRINE |
Family and domain databases
CDDi | cd03220, ABC_KpsT_Wzt, 1 hit |
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR015860, ABC_transpr_TagH-like IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51251, TAGH, 1 hit |
i Sequence
Sequence statusi: Complete.
P42954-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLKVSFRNV SKQYHLYKKQ SDKIKGLFFP AKDNGFFAVR NVSFDVYEGE
60 70 80 90 100
TIGFVGINGS GKSTMSNLLA KIIPPTSGEI EMNGQPSLIA IAAGLNNQLT
110 120 130 140 150
GRDNVRLKCL MMGLTNKEID DMYDSIVEFA EIGDFINQPV KNYSSGMKSR
160 170 180 190 200
LGFAISVHID PDILIIDEAL SVGDQTFYQK CVDRINEFKK QGKTIFFVSH
210 220 230 240 250
SIGQIEKMCD RVAWMHYGEL RMFDETKTVV KEYKAFIDWF NKLSKKEKET
260 270 280 290 300
YKKEQTEERK KEDPEAFARF RKKKKKPKSL ANAIQIAILS ILTVFMAGTM
310 320 330 340 350
FFNAPLRTIA SFGAIPQNEV KNHHGDAKGK SEERLTAINK QGFIANEKAA
360 370 380 390 400
AYKDQGLKQK ADVTLPFGTK VTVAAKGKQA AKIKFDGHSY YVKQSAVATN
410 420 430 440 450
MKHAELHATA FTSYVSQNAA SSYEYFLKFL GDSSTSIQSK LNGYTEGNKA
460 470 480 490 500
DGRKTLNFDY EKISYVLEND KATELIFHNI SPINPASLSL SDSDVLYDSS
510 520
KKRFLVNTDD QVFAVDNEEH TLTLMLK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U13832 Genomic DNA Translation: AAB03363.1 AL009126 Genomic DNA Translation: CAB15587.1 |
PIRi | S69203 |
RefSeqi | NP_391451.1, NC_000964.3 WP_003227930.1, NZ_JNCM01000034.1 |
Genome annotation databases
EnsemblBacteriai | CAB15587; CAB15587; BSU_35700 |
GeneIDi | 936513 |
KEGGi | bsu:BSU35700 |
PATRICi | fig|224308.179.peg.3865 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U13832 Genomic DNA Translation: AAB03363.1 AL009126 Genomic DNA Translation: CAB15587.1 |
PIRi | S69203 |
RefSeqi | NP_391451.1, NC_000964.3 WP_003227930.1, NZ_JNCM01000034.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
7DD0 | X-ray | 2.70 | A/B/C/D | 1-280 | [»] | |
AlphaFoldDBi | P42954 | |||||
SMRi | P42954 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | P42954, 7 interactors |
STRINGi | 224308.BSU35700 |
Protein family/group databases
TCDBi | 3.A.1.104.1, the atp-binding cassette (abc) superfamily |
Proteomic databases
jPOSTi | P42954 |
PaxDbi | P42954 |
PRIDEi | P42954 |
Genome annotation databases
EnsemblBacteriai | CAB15587; CAB15587; BSU_35700 |
GeneIDi | 936513 |
KEGGi | bsu:BSU35700 |
PATRICi | fig|224308.179.peg.3865 |
Phylogenomic databases
eggNOGi | COG1134, Bacteria |
InParanoidi | P42954 |
OMAi | CVDRINE |
Enzyme and pathway databases
BioCyci | BSUB:BSU35700-MONOMER |
Family and domain databases
CDDi | cd03220, ABC_KpsT_Wzt, 1 hit |
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR015860, ABC_transpr_TagH-like IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51251, TAGH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TAGH_BACSU | |
Accessioni | P42954Primary (citable) accession number: P42954 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | May 25, 2022 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families