Protein GZF3

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• DNA-binding transcription factor activity, RNA polymerase II-specific Source: SGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • "The yeast GATA factor Gat1 occupies a central position in nitrogen catabolite repression-sensitive gene activation."
    Georis I., Feller A., Vierendeels F., Dubois E.
    Mol Cell Biol 29:3803-3815(2009) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• sequence-specific DNA binding Source: SGDInferred from direct assayⁱ
  • "Cross regulation of four GATA factors that control nitrogen catabolic gene expression in Saccharomyces cerevisiae."
    Coffman J.A., Rai R., Loprete D.M., Cunningham T., Svetlov V., Cooper T.G.
    J Bacteriol 179:3416-3429(1997) [PubMed] [Europe PMC] [Abstract]
• zinc ion binding Source: InterPro

GO - Biological processⁱ

• maintenance of protein location in nucleus Source: SGD <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ipi">GO evidence code guide</a></p> Inferred from physical interactionⁱ
  • "The yeast GATA factor Gat1 occupies a central position in nitrogen catabolite repression-sensitive gene activation."
    Georis I., Feller A., Vierendeels F., Dubois E.
    Mol Cell Biol 29:3803-3815(2009) [PubMed] [Europe PMC] [Abstract]
• negative regulation of transcription by RNA polymerase II Source: SGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • "Cross regulation of four GATA factors that control nitrogen catabolic gene expression in Saccharomyces cerevisiae."
    Coffman J.A., Rai R., Loprete D.M., Cunningham T., Svetlov V., Cooper T.G.
    J Bacteriol 179:3416-3429(1997) [PubMed] [Europe PMC] [Abstract]
• nitrogen catabolite repression of transcription Source: SGDInferred from mutant phenotypeⁱ
  • "Cross regulation of four GATA factors that control nitrogen catabolic gene expression in Saccharomyces cerevisiae."
    Coffman J.A., Rai R., Loprete D.M., Cunningham T., Svetlov V., Cooper T.G.
    J Bacteriol 179:3416-3429(1997) [PubMed] [Europe PMC] [Abstract]
  • "Role of GATA factor Nil2p in nitrogen regulation of gene expression in Saccharomyces cerevisiae."
    Rowen D.W., Esiobu N., Magasanik B.
    J Bacteriol 179:3761-3766(1997) [PubMed] [Europe PMC] [Abstract]
• regulation of transcription by RNA polymerase II Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

• UniProt annotation
• GO - Cellular component

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

Miscellaneous databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Zinc finger

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MASQATTLRG YNIRKRDNVF EPKSSENLNS LNQSEEEGHI GRWPPLGYEA 
        60         70         80         90        100
VSAEQKSAVQ LRESQAGASI SNNMNFKAND KSFSTSTAGR MSPDTNSLHH 
       110        120        130        140        150
ILPKNQVKNN GQTMDANCNN NVSNDANVPV CKNCLTSTTP LWRRDEHGAM 
       160        170        180        190        200
LCNACGLFLK LHGKPRPISL KTDVIKSRNR KSNTNHAHNL DNFRNQTLIA 
       210        220        230        240        250
ELKGDCNIES SGRKANRVTS EDKKKKSSQL LMGTSSTAKI SKKPKTESKE 
       260        270        280        290        300
RSDSHLSATK LEVLMSGDCS RPNLKPKLPK QDTAIYQEKL LTFPSYTDVK 
       310        320        330        340        350
EYSNSAHQSA FIKERSQFNA ASFPLNASHS VTSKTGADSP QLPHLSMLLG 
       360        370        380        390        400
SLSSTSISNN GSEIVSNCNN GIASTAATLA PTSSRTTDSN PSEVPNQIRS 
       410        420        430        440        450
TMSSPDIISA KRNDPAPLSF HMASINDMLE TRDRAISNVK TETTPPHFIP 
       460        470        480        490        500
FLQSSKAPCI SKANSQSISN SVSSSDVSGR KFENHPAKDL GDQLSTKLHK 
       510        520        530        540        550
EEEIIKLKTR INELELVTDL YRRHINELDG KCRALEERLQ RTVKQEGNKG 

G                                                      

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Yeast
   Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
2. Yeast chromosome X
   Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names