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UniProtKB - P42833 (HXT14_YEAST)
Protein
Hexose transporter HXT14
Gene
HXT14
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Probable glucose transporter.
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
- galactose transmembrane transporter activity Source: SGD
GO - Biological processi
- carbohydrate transport Source: GO_Central
- hexose transmembrane transport Source: SGD
Keywordsi
Biological process | Sugar transport, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.109, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Hexose transporter HXT14 |
Gene namesi | Name:HXT14 Synonyms:HXT9 Ordered Locus Names:YNL318C ORF Names:N0345 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000005262, HXT14 |
VEuPathDBi | FungiDB:YNL318C |
Subcellular locationi
Other locations
Mitochondrion
- mitochondrion Source: SGD
Plasma Membrane
- plasma membrane Source: GO_Central
Vacuole
- fungal-type vacuole Source: SGD
Other locations
- cell periphery Source: SGD
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 56 | CytoplasmicSequence analysisAdd BLAST | 56 | |
Transmembranei | 57 – 76 | Helical; Name=1Sequence analysisAdd BLAST | 20 | |
Topological domaini | 77 – 119 | ExtracellularSequence analysisAdd BLAST | 43 | |
Transmembranei | 120 – 140 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 141 – 146 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 147 – 167 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 168 – 177 | ExtracellularSequence analysis | 10 | |
Transmembranei | 178 – 198 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 199 – 204 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 205 – 225 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 226 – 243 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 244 – 264 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 265 – 357 | CytoplasmicSequence analysisAdd BLAST | 93 | |
Transmembranei | 358 – 374 | Helical; Name=7Sequence analysisAdd BLAST | 17 | |
Topological domaini | 375 – 380 | ExtracellularSequence analysis | 6 | |
Transmembranei | 381 – 398 | Helical; Name=8Sequence analysisAdd BLAST | 18 | |
Topological domaini | 399 – 405 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 406 – 426 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 427 – 440 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 441 – 461 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 462 – 478 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 479 – 499 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 500 | ExtracellularSequence analysis | 1 | |
Transmembranei | 501 – 521 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 522 – 540 | CytoplasmicSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050403 | 1 – 540 | Hexose transporter HXT14Add BLAST | 540 |
Proteomic databases
PaxDbi | P42833 |
TopDownProteomicsi | P42833 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 35521, 20 interactors |
DIPi | DIP-8115N |
IntActi | P42833, 2 interactors |
MINTi | P42833 |
STRINGi | 4932.YNL318C |
Miscellaneous databases
RNActi | P42833, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | P42833 |
OMAi | FIFGWDV |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P42833-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTAQIPYQHS SGYISHFHNN ELDAGRGRDY NVTIKYLDDK EENIEGQAAK
60 70 80 90 100
ISHNASLHIP VLLCLVISLG GFIFGWDIGT IGGMTNMVSF QEKFGTTNII
110 120 130 140 150
HDDETIFVST KKLTDLQIGL IISIFNISCG VGALTLSKIG DWIGRKGGIW
160 170 180 190 200
FALVVYCIGI TIQILSYGRW YFLTLGRAVT GIGVGVTTVL VPMFLSENSP
210 220 230 240 250
LKIRGSMVST YQLIVTFGIL MGNILNFICE RCYKDPTQNI AWQLPLFLGY
260 270 280 290 300
IWAIIIGMSL VYVPESPQYL AKIKNDVPSA KYSFARMNGI PATDSMVIEF
310 320 330 340 350
IDDLLENNYN NEETNNESKK QSLVKRNTFE FIMGKPKLWL RLIIGMMIMA
360 370 380 390 400
FQQLSGINYF FYYGTSVFKG VGIKDPYITS IILSSVNFLS TILGIYYVEK
410 420 430 440 450
WGHKTCLLYG STNLLFYMMT YATVGTFGRE TDFSNIVLII VTCCFIFWFA
460 470 480 490 500
ITLGPVTFVL VSELFPLRTR AISMAICTFI NWMFNFLISL LTPMIVSKID
510 520 530 540
FKLGYIFAAC LLALIIFSWI LVPETRKKNE QEINKIFEPE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46259 Genomic DNA No translation available. Z71595 Genomic DNA Translation: CAA96250.1 BK006947 Genomic DNA Translation: DAA10243.1 |
PIRi | S63299 |
RefSeqi | NP_014081.1, NM_001183156.1 |
Genome annotation databases
EnsemblFungii | YNL318C_mRNA; YNL318C; YNL318C |
GeneIDi | 855398 |
KEGGi | sce:YNL318C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46259 Genomic DNA No translation available. Z71595 Genomic DNA Translation: CAA96250.1 BK006947 Genomic DNA Translation: DAA10243.1 |
PIRi | S63299 |
RefSeqi | NP_014081.1, NM_001183156.1 |
3D structure databases
SMRi | P42833 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35521, 20 interactors |
DIPi | DIP-8115N |
IntActi | P42833, 2 interactors |
MINTi | P42833 |
STRINGi | 4932.YNL318C |
Protein family/group databases
TCDBi | 2.A.1.1.109, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P42833 |
TopDownProteomicsi | P42833 |
Genome annotation databases
EnsemblFungii | YNL318C_mRNA; YNL318C; YNL318C |
GeneIDi | 855398 |
KEGGi | sce:YNL318C |
Organism-specific databases
SGDi | S000005262, HXT14 |
VEuPathDBi | FungiDB:YNL318C |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | P42833 |
OMAi | FIFGWDV |
Miscellaneous databases
PROi | PR:P42833 |
RNActi | P42833, protein |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HXT14_YEAST | |
Accessioni | P42833Primary (citable) accession number: P42833 Secondary accession number(s): D6W0M7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 158 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XIV
Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names - SIMILARITY comments
Index of protein domains and families