UniProtKB - P42597 (UTPP_ECOLI)
Protein
UTP pyrophosphatase
Gene
ygjP
Organism
Escherichia coli (strain K12)
Status
Functioni
Specifically catalyzes the hydrolysis of UTP to UMP and diphosphate in vitro, albeit at apparently slow rate. Shows no activity towards ATP, GTP, CTP, dTTP and ITP as substrates.1 Publication
Catalytic activityi
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-KW
- nucleotide binding Source: UniProtKB-KW
GO - Biological processi
- nucleotide metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase |
Biological process | Nucleotide metabolism |
Ligand | Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G7604-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ygjPImported Synonyms:upp1 Publication Ordered Locus Names:b3085, JW5514 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000169424 | 1 – 167 | UTP pyrophosphataseAdd BLAST | 167 |
Proteomic databases
PaxDbi | P42597 |
PRIDEi | P42597 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260874, 23 interactors |
STRINGi | 511145.b3085 |
Family & Domainsi
Phylogenomic databases
eggNOGi | COG1451, Bacteria |
HOGENOMi | CLU_101303_0_0_6 |
InParanoidi | P42597 |
PhylomeDBi | P42597 |
Family and domain databases
InterProi | View protein in InterPro IPR002725, DUF45 |
Pfami | View protein in Pfam PF01863, DUF45, 1 hit |
i Sequence
Sequence statusi: Complete.
P42597-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNLTYLQGY PEQLLSQVRT LINEQRLGDV LAKRYPGTHD YATDKALWQY
60 70 80 90 100
TQDLKNQFLR NAPPINKVMY DNKIHVLKNA LGLHTAVSRV QGGKLKAKVE
110 120 130 140 150
IRVATVFRNA PEPFLRMIVV HELAHLKEKE HNKAFYQLCC HMEPQYHQLE
160
FDTRLWLTQL SLGQNKI
Sequence cautioni
The sequence AAA57886 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA57886.1 Different initiation. U00096 Genomic DNA Translation: AAC76120.2 AP009048 Genomic DNA Translation: BAE77135.1 |
PIRi | B65097 |
RefSeqi | NP_417556.2, NC_000913.3 WP_001333820.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76120; AAC76120; b3085 BAE77135; BAE77135; BAE77135 |
GeneIDi | 947650 |
KEGGi | ecj:JW5514 eco:b3085 |
PATRICi | fig|511145.12.peg.3180 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA57886.1 Different initiation. U00096 Genomic DNA Translation: AAC76120.2 AP009048 Genomic DNA Translation: BAE77135.1 |
PIRi | B65097 |
RefSeqi | NP_417556.2, NC_000913.3 WP_001333820.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260874, 23 interactors |
STRINGi | 511145.b3085 |
Proteomic databases
PaxDbi | P42597 |
PRIDEi | P42597 |
Genome annotation databases
EnsemblBacteriai | AAC76120; AAC76120; b3085 BAE77135; BAE77135; BAE77135 |
GeneIDi | 947650 |
KEGGi | ecj:JW5514 eco:b3085 |
PATRICi | fig|511145.12.peg.3180 |
Organism-specific databases
EchoBASEi | EB2586 |
Phylogenomic databases
eggNOGi | COG1451, Bacteria |
HOGENOMi | CLU_101303_0_0_6 |
InParanoidi | P42597 |
PhylomeDBi | P42597 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7604-MONOMER |
Miscellaneous databases
PROi | PR:P42597 |
Family and domain databases
InterProi | View protein in InterPro IPR002725, DUF45 |
Pfami | View protein in Pfam PF01863, DUF45, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | UTPP_ECOLI | |
Accessioni | P42597Primary (citable) accession number: P42597 Secondary accession number(s): Q2M9C1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | December 4, 2007 | |
Last modified: | December 2, 2020 | |
This is version 122 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |