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Protein

Chaperone protein HtpG

Gene

htpG

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone. Has ATPase activity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HtpGUniRule annotation
Alternative name(s):
Heat shock protein HtpGUniRule annotation
High temperature protein GUniRule annotation
Gene namesi
Name:htpGUniRule annotation
Ordered Locus Names:BB_0560
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: CAFA
  • membrane Source: CAFA

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000629711 – 616Chaperone protein HtpGAdd BLAST616

Proteomic databases

PRIDEiP42555

Interactioni

Subunit structurei

Homodimer.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi224326.BB_0560

Structurei

3D structure databases

ProteinModelPortaliP42555
SMRiP42555
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 333A; substrate-bindingUniRule annotationAdd BLAST333
Regioni334 – 542BUniRule annotationAdd BLAST209
Regioni543 – 616CUniRule annotationAdd BLAST74

Sequence similaritiesi

Belongs to the heat shock protein 90 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJX Bacteria
COG0326 LUCA
KOiK04079
OMAiSDHEIFL

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di1.20.120.790, 1 hit
3.30.565.10, 1 hit
HAMAPiMF_00505 HSP90, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR019805 Heat_shock_protein_90_CS
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020575 Hsp90_N
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
PIRSFiPIRSF002583 Hsp90, 1 hit
PRINTSiPR00775 HEATSHOCK90
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS00298 HSP90, 1 hit

Sequencei

Sequence statusi: Complete.

P42555-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKQFDTEVN DLLYLIIHSL YSHKEIFLRE LISNASDAID KLKFLSLTNE
60 70 80 90 100
KFKNIALEPK IEISFDDKSI LIKDNGIGMD EQDLTNHLGV IAKSGTKEFI
110 120 130 140 150
NNLKQDEKKS ASLIGQFGVG FYSAFIVSEK VEVTSKKALE SDAYIWSSDG
160 170 180 190 200
KTGYEIEKAK KEESGTEIKL YLNKEGLEYA NKWKIQEIIK KYSNHINYPI
210 220 230 240 250
YIKYSEPIMK DGKQEGIEEK EEKLNETTAL WTKNKSEIKA EEYNEFYKNT
260 270 280 290 300
TFDYENPLMH IHTKAEGNLE YTNLFYVPSK APYDLYYPNT KPGVKLFINR
310 320 330 340 350
IFITDSEGSL LPNYLRFIKG IIDCQDLPLN VSREILQQNK ILSKIKSSSV
360 370 380 390 400
KKILSELEKL SKKNPEKFSE FSKEFGRCIK EGVYSDFENR EKLISLIRFK
410 420 430 440 450
SSSVDGFVSF KEYKERMNES QKSIYYITGG KENILKENPI VAAYKEKGFE
460 470 480 490 500
ILIMDDELDE AILNLIPEYE GLKLKAINKN ETSNELKDEN FKKIEEEFKD
510 520 530 540 550
TLTKVKEILK DHIKEVNLSA TLIKEPSAII IDSNDPTYQM QKIMLSMGQE
560 570 580 590 600
VKEIKPILEL NPNNKIVQNL KNLEPEKLEK ISILLFEEAM LTSGMPSKNP
610
GKFINIINEF IEKDFL
Length:616
Mass (Da):71,219
Last modified:October 1, 1996 - v2
Checksum:iD676552F48DBEE84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51878 Genomic DNA Translation: AAA97469.1
AE000783 Genomic DNA Translation: AAC66919.2
L32145 Genomic DNA Translation: AAC41403.1
PIRiG70169
RefSeqiNP_212694.2, NC_001318.1
WP_002557148.1, NC_001318.1

Genome annotation databases

EnsemblBacteriaiAAC66919; AAC66919; BB_0560
GeneIDi1195407
KEGGibbu:BB_0560
PATRICifig|224326.49.peg.951

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51878 Genomic DNA Translation: AAA97469.1
AE000783 Genomic DNA Translation: AAC66919.2
L32145 Genomic DNA Translation: AAC41403.1
PIRiG70169
RefSeqiNP_212694.2, NC_001318.1
WP_002557148.1, NC_001318.1

3D structure databases

ProteinModelPortaliP42555
SMRiP42555
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224326.BB_0560

Proteomic databases

PRIDEiP42555

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC66919; AAC66919; BB_0560
GeneIDi1195407
KEGGibbu:BB_0560
PATRICifig|224326.49.peg.951

Phylogenomic databases

eggNOGiENOG4105CJX Bacteria
COG0326 LUCA
KOiK04079
OMAiSDHEIFL

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di1.20.120.790, 1 hit
3.30.565.10, 1 hit
HAMAPiMF_00505 HSP90, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR019805 Heat_shock_protein_90_CS
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020575 Hsp90_N
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
PIRSFiPIRSF002583 Hsp90, 1 hit
PRINTSiPR00775 HEATSHOCK90
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS00298 HSP90, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiHTPG_BORBU
AccessioniPrimary (citable) accession number: P42555
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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