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UniProtKB - P42268 (NDD_BPR70)
Protein
Nucleoid disruption protein
Gene
ndd
Organism
Enterobacteria phage RB70 (Bacteriophage RB70)
Status
Functioni
Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation. Only the architecture of the nucleoid is affected. May act on the host chromosomal sequences that determine the structure of the nucleoid. Binds to dsDNA but not to ssDNA.
By similarityGO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- inhibition of host DNA replication by virus Source: UniProtKB-KW
- modulation by virus of host cell cycle Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | Host-virus interaction, Inhibition of host DNA replication by virus, Modulation of host cell cycle by virus |
Names & Taxonomyi
Protein namesi | Recommended name: Nucleoid disruption proteinAlternative name(s): Nuclear disruption protein |
Gene namesi | Name:ndd |
Organismi | Enterobacteria phage RB70 (Bacteriophage RB70) |
Taxonomic identifieri | 36338 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Myoviridae › Tevenvirinae › Tequatrovirus › unclassified Tequatrovirus |
Virus hosti | Escherichia coli [TaxID: 562] |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000164965 | 1 – 147 | Nucleoid disruption proteinAdd BLAST | 147 |
Structurei
Family & Domainsi
Family and domain databases
InterProi | View protein in InterPro IPR009514, Phage_Ndd |
Pfami | View protein in Pfam PF06591, Phage_T4_Ndd, 1 hit |
i Sequence
Sequence statusi: Complete.
P42268-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKYMTVTDLN NAGATVIGTI KGGEWFLGTP HKDILSKPGF YFLVSEFDGS
60 70 80 90 100
CVSARFYVGN QRSKQGFSAV LSHIRQRRSQ LARTIANNNM AYTVFYLPAS
110 120 130 140
KMKPLTTGFG KGQLALAFTR NHHSEYQTLE EMNRMLADNF KFVLQAY
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
InterProi | View protein in InterPro IPR009514, Phage_Ndd |
Pfami | View protein in Pfam PF06591, Phage_T4_Ndd, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NDD_BPR70 | |
Accessioni | P42268Primary (citable) accession number: P42268 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | November 1, 1995 | |
Last modified: | February 23, 2022 | |
This is version 37 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |