Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sensory rhodopsin-2

Gene

sop2

Organism
Natronomonas pharaonis (Natronobacterium pharaonis)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Photophobic photoreceptor responsible for the negative phototaxis. Activates the sensory rhodopsin II transducer (HTR-II) in response to blue light.3 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionPhotoreceptor protein, Receptor, Retinal protein
Biological process
LigandChromophore

Protein family/group databases

TCDBi3.E.1.3.3 the ion-translocating microbial rhodopsin (mr) family

Names & Taxonomyi

Protein namesi
Recommended name:
Sensory rhodopsin-2
Alternative name(s):
Sensory rhodopsin II
Short name:
SR-II
Gene namesi
Name:sop2
Synonyms:sopII
OrganismiNatronomonas pharaonis (Natronobacterium pharaonis)
Taxonomic identifieri2257 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHaloarculaceaeNatronomonas

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3Extracellular3
Transmembranei4 – 25Helical; Name=Helix AAdd BLAST22
Topological domaini26 – 33Cytoplasmic8
Transmembranei34 – 55Helical; Name=Helix BAdd BLAST22
Topological domaini56 – 69ExtracellularAdd BLAST14
Transmembranei70 – 91Helical; Name=Helix CAdd BLAST22
Topological domaini92 – 94Cytoplasmic3
Transmembranei95 – 117Helical; Name=Helix DAdd BLAST23
Topological domaini118 – 121Extracellular4
Transmembranei122 – 149Helical; Name=Helix EAdd BLAST28
Topological domaini150 – 153Cytoplasmic4
Transmembranei154 – 181Helical; Name=Helix FAdd BLAST28
Topological domaini182 – 189Extracellular8
Transmembranei190 – 222Helical; Name=Helix GAdd BLAST33
Topological domaini223 – 239CytoplasmicAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001962821 – 239Sensory rhodopsin-2Add BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei205N6-(retinylidene)lysine1

Proteomic databases

PRIDEiP42196

Interactioni

Subunit structurei

Homodimer. Interacts with HTR-II.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
htr2P422595EBI-1034509,EBI-1034515

Protein-protein interaction databases

DIPiDIP-35282N
IntActiP42196, 1 interactor

Structurei

Secondary structure

1239
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP42196
SMRiP42196
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP42196

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG02810 Archaea
COG5524 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR001425 Arc/bac/fun_rhodopsins
IPR018229 Rhodopsin_retinal_BS
PANTHERiPTHR28286 PTHR28286, 1 hit
PfamiView protein in Pfam
PF01036 Bac_rhodopsin, 1 hit
PRINTSiPR00251 BACTRLOPSIN
SMARTiView protein in SMART
SM01021 Bac_rhodopsin, 1 hit
PROSITEiView protein in PROSITE
PS00950 BACTERIAL_OPSIN_1, 1 hit
PS00327 BACTERIAL_OPSIN_RET, 1 hit

Sequencei

Sequence statusi: Complete.

P42196-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGLTTLFWL GAIGMLVGTL AFAWAGRDAG SGERRYYVTL VGISGIAAVA
60 70 80 90 100
YVVMALGVGW VPVAERTVFA PRYIDWILTT PLIVYFLGLL AGLDSREFGI
110 120 130 140 150
VITLNTVVML AGFAGAMVPG IERYALFGMG AVAFLGLVYY LVGPMTESAS
160 170 180 190 200
QRSSGIKSLY VRLRNLTVIL WAIYPFIWLL GPPGVALLTP TVDVALIVYL
210 220 230
DLVTKVGFGF IALDAAATLR AEHGESLAGV DTDAPAVAD
Length:239
Mass (Da):25,355
Last modified:November 1, 1995 - v1
Checksum:iC0E93EAF341B6B19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z35086 Genomic DNA Translation: CAA84469.1
PIRiS55300

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z35086 Genomic DNA Translation: CAA84469.1
PIRiS55300

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GU8X-ray2.27A1-239[»]
1GUEX-ray2.27A1-239[»]
1H2SX-ray1.93A1-225[»]
1H68X-ray2.10A1-239[»]
1JGJX-ray2.40A1-217[»]
2F93X-ray2.00A2-239[»]
2F95X-ray2.20A2-239[»]
3QAPX-ray1.90A1-239[»]
3QDCX-ray2.50A1-239[»]
4GYCX-ray2.05A1-239[»]
5JJEX-ray1.90A2-239[»]
5JJFX-ray1.90A2-239[»]
5JJJX-ray2.50A2-239[»]
5JJNX-ray2.25A/C2-239[»]
ProteinModelPortaliP42196
SMRiP42196
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-35282N
IntActiP42196, 1 interactor

Protein family/group databases

TCDBi3.E.1.3.3 the ion-translocating microbial rhodopsin (mr) family

Proteomic databases

PRIDEiP42196

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiarCOG02810 Archaea
COG5524 LUCA

Miscellaneous databases

EvolutionaryTraceiP42196

Family and domain databases

InterProiView protein in InterPro
IPR001425 Arc/bac/fun_rhodopsins
IPR018229 Rhodopsin_retinal_BS
PANTHERiPTHR28286 PTHR28286, 1 hit
PfamiView protein in Pfam
PF01036 Bac_rhodopsin, 1 hit
PRINTSiPR00251 BACTRLOPSIN
SMARTiView protein in SMART
SM01021 Bac_rhodopsin, 1 hit
PROSITEiView protein in PROSITE
PS00950 BACTERIAL_OPSIN_1, 1 hit
PS00327 BACTERIAL_OPSIN_RET, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBACS2_NATPH
AccessioniPrimary (citable) accession number: P42196
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 10, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again