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UniProtKB - P42087 (HUTM_BACSU)
Protein
Putative histidine permease
Gene
hutM
Organism
Bacillus subtilis (strain 168)
Status
Functioni
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: GO_Central
GO - Biological processi
- amino acid transmembrane transport Source: GO_Central
Keywordsi
Biological process | Amino-acid transport, Transport |
Enzyme and pathway databases
BioCyci | BSUB:BSU39390-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative histidine permease |
Gene namesi | Name:hutM Ordered Locus Names:BSU39390 ORF Names:EE57D |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 40 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 44 – 64 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 87 – 107 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 127 – 147 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 162 – 182 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 199 – 219 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 246 – 266 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 277 – 297 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 341 – 361 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 363 – 383 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 410 – 430 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 434 – 454 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054203 | 1 – 475 | Putative histidine permeaseAdd BLAST | 475 |
Proteomic databases
PaxDbi | P42087 |
Family & Domainsi
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0833, Bacteria |
InParanoidi | P42087 |
OMAi | RTVIFFI |
PhylomeDBi | P42087 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P42087-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNLQENSSQQ LKRTMKSRHL FMISLGGVIG TGLFLSTGYT LHQAGPGGTI
60 70 80 90 100
LAYVIGGLMM YLVMQCLGEL SVAMPVTGSF QKYATTFIGP STGFMVGIMY
110 120 130 140 150
WINWVVTVGS EFTASGILMQ RWFPDSSVWM WSAIFAALLF ICNAFSVKLF
160 170 180 190 200
AETEFWFSSV KIVTIILFII LGGAAMFGLI SLNGTADAPM LSNFTDHGGL
210 220 230 240 250
FPNGFLAVFI AMISVSFAFS GTELIGVTAG ESANPQKDIP RSIRNVAWRT
260 270 280 290 300
VIFFIGAVFI LSGLISWKDA GVIESPFVAV FAEIGIPYAA DIMNFVILTA
310 320 330 340 350
LLSVANSGLY ASTRMMWSLA NENMISSRFK KVTSKGIPLN ALMISMAVSC
360 370 380 390 400
LSLVSSIVAP GTVYVVMVAI AGFAGVVVWM SIALSQLLFR KRFLKKGGDV
410 420 430 440 450
KDLTFRTPLY PLMPIAALLL CSASCIGLAF DPNQRIALFC GVPCIILCYL
460 470
IYHFKRNVTK AKKISQEEYP ADHIL
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 74 – 75 | MP → NA in BAA06640 (PubMed:7704263).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D31856 Genomic DNA Translation: BAA06640.1 AL009126 Genomic DNA Translation: CAB15975.2 X82174 Genomic DNA No translation available. D45912 Genomic DNA Translation: BAA08340.1 |
PIRi | E69643 |
RefSeqi | NP_391818.2, NC_000964.3 WP_003227134.1, NZ_JNCM01000034.1 |
Genome annotation databases
EnsemblBacteriai | CAB15975; CAB15975; BSU_39390 |
GeneIDi | 938565 |
KEGGi | bsu:BSU39390 |
PATRICi | fig|224308.179.peg.4264 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D31856 Genomic DNA Translation: BAA06640.1 AL009126 Genomic DNA Translation: CAB15975.2 X82174 Genomic DNA No translation available. D45912 Genomic DNA Translation: BAA08340.1 |
PIRi | E69643 |
RefSeqi | NP_391818.2, NC_000964.3 WP_003227134.1, NZ_JNCM01000034.1 |
3D structure databases
SMRi | P42087 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU39390 |
Proteomic databases
PaxDbi | P42087 |
Genome annotation databases
EnsemblBacteriai | CAB15975; CAB15975; BSU_39390 |
GeneIDi | 938565 |
KEGGi | bsu:BSU39390 |
PATRICi | fig|224308.179.peg.4264 |
Phylogenomic databases
eggNOGi | COG0833, Bacteria |
InParanoidi | P42087 |
OMAi | RTVIFFI |
PhylomeDBi | P42087 |
Enzyme and pathway databases
BioCyci | BSUB:BSU39390-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HUTM_BACSU | |
Accessioni | P42087Primary (citable) accession number: P42087 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | July 28, 2009 | |
Last modified: | February 23, 2022 | |
This is version 125 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families