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Entry version 138 (07 Oct 2020)
Sequence version 3 (12 Aug 2020)
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Protein

Dendrite extension defective protein 1

Gene

dex-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Along with dyf-7, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development (PubMed:19344940). Promotes seam cell remodeling during the dauer phase (PubMed:30409788). Plays a role in positively regulating locomotion during the dauer phase (PubMed:30409788).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • amphid sensory organ dendrite retrograde extension Source: WormBase
  • cell-matrix adhesion Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNeurogenesis
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dendrite extension defective protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dex-1Imported
ORF Names:D1044.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
D1044.2a ; CE44889 ; WBGene00017028 ; dex-1
D1044.2b ; CE44959 ; WBGene00017028 ; dex-1
D1044.2c ; CE45008 ; WBGene00017028 ; dex-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini43 – 1005ExtracellularSequence analysisAdd BLAST963
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1006 – 1026HelicalSequence analysisAdd BLAST21
Topological domaini1027 – 1037CytoplasmicSequence analysisAdd BLAST11

Keywords - Cellular componenti

Cell projection, Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 41Sequence analysisAdd BLAST41
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000778242 – 1137Dendrite extension defective protein 1CuratedAdd BLAST1096

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi240N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi413 ↔ 426PROSITE-ProRule annotation
Glycosylationi416N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi420 ↔ 435PROSITE-ProRule annotation
Disulfide bondi437 ↔ 449PROSITE-ProRule annotation
Glycosylationi571N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi756N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

May be proteolytically cleaved and secreted.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P41950

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P41950

PeptideAtlas

More...
PeptideAtlasi
P41950

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression is first apparent in bean-stage embryos, peaks in late embryogenesis, reduces in L1 larvae and is negligible in later larval stages and adults (PubMed:19344940). In the embryo, expressed in the excretory cell and, during dendrite formation, in the non-neuronal cells surrounding the sensory neurons, including hypodermal cells (PubMed:19344940). Expressed in pharyngeal cells throughout the larval stages (PubMed:30409788). Expression in the seam cells and glia socket cells of the anterior and posterior deirid neurons begins at the L2 pre-dauer stage and persists throughout the dauer phase (PubMed:30409788). During the dauer phase expressed along the length of the animal above seam cells, alternating between alae under the outer ridges and below the lateral ridge (PubMed:30409788).2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.D1044.2c

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P41950

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini163 – 302NIDO 1PROSITE-ProRule annotationAdd BLAST140
Domaini409 – 450EGF-like; calcium-bindingPROSITE-ProRule annotationAdd BLAST42
Domaini519 – 659NIDO 2PROSITE-ProRule annotationAdd BLAST141

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4291, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P41950

Database of Orthologous Groups

More...
OrthoDBi
138133at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR024731, EGF_dom
IPR003886, NIDO_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12947, EGF_3, 1 hit
PF06119, NIDO, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 1 hit
SM00179, EGF_CA, 1 hit
SM00539, NIDO, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS01186, EGF_2, 2 hits
PS50026, EGF_3, 1 hit
PS01187, EGF_CA, 1 hit
PS51220, NIDO, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform cImported (identifier: P41950-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLAHTHRINK CLYGQNQMRN RHALLGALPP IFLLLLPLIS CMKFDPERIA
60 70 80 90 100
ARLRIDEKWD QLDAFQSIKS RRGRQIQPKE ISIQVTAPLF SSRLFDYGTT
110 120 130 140 150
AGDEELPQAL DVGKKLDLVH PISFFGSDYK TIYILSNGAV GFEASSRSYK
160 170 180 190 200
SGILPSSTRF LAPFWNRNDL RNGGKVYYRE VTKGRVLERG QSEIRYQYDK
210 220 230 240 250
NVKVKSALII TWDKMQPLNT AALPEENTNT FQAAIFITAN GTFANFIYSN
260 270 280 290 300
IGWTQGAEAG FNAGDATNHF KLPTSGTPNI MYLEEYGNTG IPGEWMFELS
310 320 330 340 350
ELRVISCKSG IKGDTCDQEC SNGEWGPDCA YCCHCSEGTC HPISGDCQRG
360 370 380 390 400
CATCWDGVAC QTRQEKCATK TQCASNALSF NDYDRCGEPI QRCQCLNGYK
410 420 430 440 450
GDGYNNCEDV DECKTNSTIC HKNAICTNTP GRYFCMCKEG FSGDGQNDCS
460 470 480 490 500
QSFLFQYDTH HQLPRKKNSK MEWNLKKPLK IFGETTEKLT VTSTGLIAIN
510 520 530 540 550
EVNRDNGRLE DMQLVGIAPF FGPIDLSRNG AVSVEEVDDV EVLRRVTRTI
560 570 580 590 600
GENYNDPTFV AKSALVVTFS NVTDGRQTKG NTFQALLIDG SNSKNEKMTF
610 620 630 640 650
VELMYRDLPW ASGAEAGILS SDASSSILLP ASGTEAISQL SKNSNIKQPG
660 670 680 690 700
TWLYRIDKAQ LMPCAQPIQV PPYCDRLLST APRLPSKLLE EKKEGLTLPS
710 720 730 740 750
PGAFLVDQPS ETIVPTLVRG GGTVTRGRNV LTVTTSPIGN QQRQQTTKAV
760 770 780 790 800
TRPRPNFSST PHRPIVSLSD EDFELGPDAF EVTFPPFVTV QPELFRPNQR
810 820 830 840 850
NGVQKSTQRP LPDFSIRTPL KEEATTSVPR EKTSSAAPAH SPIEEMSENE
860 870 880 890 900
ESPFEAGSFD GEAVKFNEEL EAIDKALQTT KKQRPELSVT PQPEDLSGDA
910 920 930 940 950
RVIETTEEDE EEAEISTETT TEMSSTTTTT KAHTTTTTMM IPTEAPPSIF
960 970 980 990 1000
VFTTTQKPRA QSTTQKRIIV QQPSIVVNSQ PPKQRNDNQP TVNVGHAEEQ
1010 1020 1030 1040 1050
SPRLAILLPV MIILAWLVIL VCIGAVVCCK RRNSRESSQL RAMYGAAYGV
1060 1070 1080 1090 1100
RPTAYESKRK ESTYEDHLER AARLSGQPAL SGQQAGKVSL YGSYWNLEPL
1110 1120 1130
SNHSPARLST QERQSPPSFV NNGYTNQTTR YTYAGHY
Length:1,137
Mass (Da):126,144
Last modified:August 12, 2020 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5554994531B9183A
GO
Isoform aImported (identifier: P41950-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: Missing.
     1084-1098: QAGKVSLYGSYWNLE → QKTTSESTLIECVRL
     1099-1137: Missing.

Show »
Length:1,081
Mass (Da):119,704
Checksum:i1C9EC453140E0A4F
GO
Isoform bImported (identifier: P41950-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: Missing.
     1085-1129: Missing.

Show »
Length:1,075
Mass (Da):119,154
Checksum:iCB2F04340D99FE63
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0606161 – 17Missing in isoform a and isoform b. CuratedAdd BLAST17
Alternative sequenceiVSP_0606171084 – 1098QAGKV…YWNLE → QKTTSESTLIECVRL in isoform a. CuratedAdd BLAST15
Alternative sequenceiVSP_0606181085 – 1129Missing in isoform b. CuratedAdd BLAST45
Alternative sequenceiVSP_0606191099 – 1137Missing in isoform a. CuratedAdd BLAST39

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CCD68377.1
BX284603 Genomic DNA Translation: CCD68378.1
BX284603 Genomic DNA Translation: CCD68379.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T15884

NCBI Reference Sequences

More...
RefSeqi
NP_498181.3, NM_065780.4 [P41950-2]
NP_498182.2, NM_065781.4 [P41950-1]
NP_498183.2, NM_065782.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
D1044.2a.1; D1044.2a.1; WBGene00017028 [P41950-2]
D1044.2b.1; D1044.2b.1; WBGene00017028 [P41950-3]
D1044.2c.1; D1044.2c.1; WBGene00017028 [P41950-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
175761

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_D1044.2

UCSC genome browser

More...
UCSCi
D1044.2c, c. elegans [P41950-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CCD68377.1
BX284603 Genomic DNA Translation: CCD68378.1
BX284603 Genomic DNA Translation: CCD68379.1
PIRiT15884
RefSeqiNP_498181.3, NM_065780.4 [P41950-2]
NP_498182.2, NM_065781.4 [P41950-1]
NP_498183.2, NM_065782.3

3D structure databases

SMRiP41950
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.D1044.2c

Proteomic databases

EPDiP41950
PaxDbiP41950
PeptideAtlasiP41950

Genome annotation databases

EnsemblMetazoaiD1044.2a.1; D1044.2a.1; WBGene00017028 [P41950-2]
D1044.2b.1; D1044.2b.1; WBGene00017028 [P41950-3]
D1044.2c.1; D1044.2c.1; WBGene00017028 [P41950-1]
GeneIDi175761
KEGGicel:CELE_D1044.2
UCSCiD1044.2c, c. elegans [P41950-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
175761
WormBaseiD1044.2a ; CE44889 ; WBGene00017028 ; dex-1
D1044.2b ; CE44959 ; WBGene00017028 ; dex-1
D1044.2c ; CE45008 ; WBGene00017028 ; dex-1

Phylogenomic databases

eggNOGiKOG4291, Eukaryota
InParanoidiP41950
OrthoDBi138133at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P41950

Family and domain databases

InterProiView protein in InterPro
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR024731, EGF_dom
IPR003886, NIDO_dom
PfamiView protein in Pfam
PF12947, EGF_3, 1 hit
PF06119, NIDO, 2 hits
SMARTiView protein in SMART
SM00181, EGF, 1 hit
SM00179, EGF_CA, 1 hit
SM00539, NIDO, 2 hits
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS01186, EGF_2, 2 hits
PS50026, EGF_3, 1 hit
PS01187, EGF_CA, 1 hit
PS51220, NIDO, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDEX1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P41950
Secondary accession number(s): D7SFI8
, Q8TA75, Q95QP5, Q95QP6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: August 12, 2020
Last modified: October 7, 2020
This is version 138 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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