UniProtKB - P41815 (BAP3_YEAST)
Protein
Valine amino-acid permease
Gene
BAP3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Involved in transport of isoleucine, leucine, valine, cysteine, methionine, phenylalanine, tyrosine and tryptophan.2 Publications
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: SGD
GO - Biological processi
- amino acid transmembrane transport Source: GO_Central
- amino acid transport Source: SGD
- transmembrane transport Source: SGD
Keywordsi
Biological process | Amino-acid transport, Transport |
Enzyme and pathway databases
BioCyci | YEAST:G3O-29659-MONOMER |
Protein family/group databases
TCDBi | 2.A.3.10.27, the amino acid-polyamine-organocation (apc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Valine amino-acid permeaseAlternative name(s): Branched-chain amino-acid permease 3 |
Gene namesi | Name:BAP3 Synonyms:PAP1 Ordered Locus Names:YDR046C ORF Names:YD9609.02C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000002453, BAP3 |
VEuPathDBi | FungiDB:YDR046C |
Subcellular locationi
Other locations
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
Mitochondrion
- mitochondrion Source: SGD
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 95 | CytoplasmicSequence analysisAdd BLAST | 95 | |
Transmembranei | 96 – 116 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 117 – 119 | ExtracellularSequence analysis | 3 | |
Transmembranei | 120 – 140 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 141 – 169 | CytoplasmicSequence analysisAdd BLAST | 29 | |
Transmembranei | 170 – 190 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 191 – 206 | ExtracellularSequence analysisAdd BLAST | 16 | |
Transmembranei | 207 – 227 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 228 – 238 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 239 – 259 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 260 – 284 | ExtracellularSequence analysisAdd BLAST | 25 | |
Transmembranei | 285 – 305 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 306 – 323 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 324 – 344 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 345 – 377 | ExtracellularSequence analysisAdd BLAST | 33 | |
Transmembranei | 378 – 398 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 399 – 423 | CytoplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 424 – 444 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 445 – 449 | ExtracellularSequence analysis | 5 | |
Transmembranei | 450 – 470 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 471 – 502 | CytoplasmicSequence analysisAdd BLAST | 32 | |
Transmembranei | 503 – 523 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 524 – 531 | ExtracellularSequence analysis | 8 | |
Transmembranei | 532 – 552 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 553 – 604 | CytoplasmicSequence analysisAdd BLAST | 52 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054147 | 1 – 604 | Valine amino-acid permeaseAdd BLAST | 604 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 14 | PhosphoserineBy similarity | 1 | |
Modified residuei | 79 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | P41815 |
PRIDEi | P41815 |
PTM databases
iPTMneti | P41815 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 32101, 165 interactors |
DIPi | DIP-7900N |
IntActi | P41815, 11 interactors |
MINTi | P41815 |
STRINGi | 4932.YDR046C |
Miscellaneous databases
RNActi | P41815, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1286, Eukaryota |
GeneTreei | ENSGT00940000176401 |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | P41815 |
OMAi | FTWSGIM |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004762, Amino_acid_permease_fungi IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
TIGRFAMsi | TIGR00913, 2A0310, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P41815-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDPIVTSSK MEKSAEFEVT DSALYNNFNT STTASLTPEI KEHSEESRNG
60 70 80 90 100
LVHRFVDSFR RAESQRLEED NDLEDGTKSM KSNNHLKKSM KSRHVVMMSL
110 120 130 140 150
GTGIGTGLLV ANAKGLSLAG PGSLVIGYVM VSFVTYFMVQ AAGEMGVTYP
160 170 180 190 200
TLPGNFNAYN SIFISKSFGF ATTWLFCIQW LTVLPLELIT SSMTVKYWND
210 220 230 240 250
TINADVFIVI FYVFLLFIHF FGVKAYGETE FIFNSCKILM VAGFIILSVV
260 270 280 290 300
INCGGAGVDG YIGGKYWRDP GSFAEGSGAT RFKGICYILV SAYFSFGGIE
310 320 330 340 350
LFVLSINEQS NPRKSTPVAA KRSVYRILII YLLTMILIGF NVPHNNDQLM
360 370 380 390 400
GSGGSATHAS PYVLAASIHK VRVIPHIINA VILISVISVA NSALYAAPRL
410 420 430 440 450
MCSLAQQGYA PKFLNYIDRE GRPLRALVVC SLVGVVGFVA CSPQEEQAFT
460 470 480 490 500
WLAAIAGLSE LFTWSGIMLS HIRFRKAMKV QGRSLDEVGY KANTGIWGSY
510 520 530 540 550
YGVFFNMLVF MAQFWVALSP IGNGGKCDAQ AFFESYLAAP LWIFMYVGYM
560 570 580 590 600
VYKRDFTFLN PLDKIDLDFH RRVYDPEIMR QEDEENKERL KNSSIFVRVY
KFWC
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 573 – 575 | VYD → GLR in CAA52970 (PubMed:8200527).Curated | 3 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75076 Genomic DNA Translation: CAA52970.1 Z49209 Genomic DNA Translation: CAA89077.1 BK006938 Genomic DNA Translation: DAA11894.1 |
PIRi | S54032 |
RefSeqi | NP_010331.3, NM_001180354.3 |
Genome annotation databases
EnsemblFungii | YDR046C_mRNA; YDR046C; YDR046C |
GeneIDi | 851616 |
KEGGi | sce:YDR046C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75076 Genomic DNA Translation: CAA52970.1 Z49209 Genomic DNA Translation: CAA89077.1 BK006938 Genomic DNA Translation: DAA11894.1 |
PIRi | S54032 |
RefSeqi | NP_010331.3, NM_001180354.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 32101, 165 interactors |
DIPi | DIP-7900N |
IntActi | P41815, 11 interactors |
MINTi | P41815 |
STRINGi | 4932.YDR046C |
Protein family/group databases
TCDBi | 2.A.3.10.27, the amino acid-polyamine-organocation (apc) family |
PTM databases
iPTMneti | P41815 |
Proteomic databases
PaxDbi | P41815 |
PRIDEi | P41815 |
Genome annotation databases
EnsemblFungii | YDR046C_mRNA; YDR046C; YDR046C |
GeneIDi | 851616 |
KEGGi | sce:YDR046C |
Organism-specific databases
SGDi | S000002453, BAP3 |
VEuPathDBi | FungiDB:YDR046C |
Phylogenomic databases
eggNOGi | KOG1286, Eukaryota |
GeneTreei | ENSGT00940000176401 |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | P41815 |
OMAi | FTWSGIM |
Enzyme and pathway databases
BioCyci | YEAST:G3O-29659-MONOMER |
Miscellaneous databases
PROi | PR:P41815 |
RNActi | P41815, protein |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004762, Amino_acid_permease_fungi IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
TIGRFAMsi | TIGR00913, 2A0310, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BAP3_YEAST | |
Accessioni | P41815Primary (citable) accession number: P41815 Secondary accession number(s): D6VS34 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1995 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 163 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names - SIMILARITY comments
Index of protein domains and families