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Entry version 157 (13 Feb 2019)
Sequence version 2 (10 Oct 2002)
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Protein

Protein BUD31 homolog

Gene

BUD31

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the pre-mRNA splicing process (PubMed:28502770, PubMed:28076346). May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity (PubMed:25091737).1 Publication2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing, mRNA splicing, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-72163 mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein BUD31 homolog1 Publication
Alternative name(s):
Protein EDG-21 Publication
Protein G10 homolog1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BUD31
Synonyms:EDG2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000106245.9

Human Gene Nomenclature Database

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HGNCi
HGNC:29629 BUD31

Online Mendelian Inheritance in Man (OMIM)

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MIMi
603477 gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_P41223

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
8896

Open Targets

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OpenTargetsi
ENSG00000106245

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA144596513

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
BUD31

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001938971 – 144Protein BUD31 homologAdd BLAST144

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei125N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P41223

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P41223

MaxQB - The MaxQuant DataBase

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MaxQBi
P41223

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P41223

PeptideAtlas

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PeptideAtlasi
P41223

PRoteomics IDEntifications database

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PRIDEi
P41223

ProteomicsDB human proteome resource

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ProteomicsDBi
55432

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P41223

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P41223

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in epithelial and stromal cells in benign prostate hyperplasia tissue (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000106245 Expressed in 235 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P41223 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P41223 HS

Organism-specific databases

Human Protein Atlas

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HPAi
HPA028943

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Identified in the spliceosome C complex (PubMed:28502770, PubMed:28076346). May interact with AR (PubMed:25091737).1 Publication2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
114413, 48 interactors

CORUM comprehensive resource of mammalian protein complexes

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CORUMi
P41223

Protein interaction database and analysis system

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IntActi
P41223, 26 interactors

Molecular INTeraction database

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MINTi
P41223

STRING: functional protein association networks

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STRINGi
9606.ENSP00000222969

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1144
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4OEDX-ray2.79B56-70[»]
4OH6X-ray3.56B56-70[»]
4OKBX-ray2.95B56-70[»]
5MQFelectron microscopy5.90Q1-144[»]
5XJCelectron microscopy3.60N1-144[»]
5YZGelectron microscopy4.10N1-144[»]
5Z56electron microscopy5.10N1-144[»]
5Z57electron microscopy6.50N1-144[»]
6FF4electron microscopy16.00Q1-144[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P41223

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P41223

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni59 – 67Interaction with AR1 Publication9

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi2 – 10Nuclear localization signalSequence analysis9

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains a short sequence motif (Phe-Xaa-Xaa-Phe-Tyr) that can bind to AR and may modulate AR activity.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BUD31 (G10) family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3404 Eukaryota
COG5132 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000014300

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000235066

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG080938

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P41223

KEGG Orthology (KO)

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KOi
K12873

Identification of Orthologs from Complete Genome Data

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OMAi
CRGCSSD

Database of Orthologous Groups

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OrthoDBi
1236198at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P41223

TreeFam database of animal gene trees

More...
TreeFami
TF105609

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR018230 BUD31/G10-rel_CS
IPR001748 G10

The PANTHER Classification System

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PANTHERi
PTHR19411 PTHR19411, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF01125 G10, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00322 G10

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00997 G10_1, 1 hit
PS00998 G10_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P41223-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPKVKRSRKA PPDGWELIEP TLDELDQKMR EAETEPHEGK RKVESLWPIF
60 70 80 90 100
RIHHQKTRYI FDLFYKRKAI SRELYEYCIK EGYADKNLIA KWKKQGYENL
110 120 130 140
CCLRCIQTRD TNFGTNCICR VPKSKLEVGR IIECTHCGCR GCSG
Length:144
Mass (Da):17,000
Last modified:October 10, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i520B8E74C97D0926
GO
Isoform 2 (identifier: P41223-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     129-144: GRIIECTHCGCRGCSG → VMSDTQAWCCFQLKILP

Note: No experimental confirmation available.
Show »
Length:145
Mass (Da):17,331
Checksum:i00598D743480CF95
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JCD9C9JCD9_HUMAN
Protein BUD31 homolog
BUD31
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCN7F8WCN7_HUMAN
Protein BUD31 homolog
BUD31
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12P → Q in AAA20008 (PubMed:7841202).Curated1
Sequence conflicti12P → Q in AAB33291 (PubMed:7841202).Curated1
Sequence conflicti24E → Q in AAA20008 (PubMed:7841202).Curated1
Sequence conflicti24E → Q in AAB33291 (PubMed:7841202).Curated1
Sequence conflicti70I → Y in AAA20008 (PubMed:7841202).Curated1
Sequence conflicti70I → Y in AAB33291 (PubMed:7841202).Curated1
Sequence conflicti75 – 79YEYCI → LDICY in AAA20008 (PubMed:7841202).Curated5
Sequence conflicti83Y → L in AAA20008 (PubMed:7841202).Curated1
Sequence conflicti83Y → L in AAB33291 (PubMed:7841202).Curated1
Sequence conflicti89I → L in AAA20008 (PubMed:7841202).Curated1
Sequence conflicti89I → L in AAB33291 (PubMed:7841202).Curated1
Sequence conflicti97 – 98YE → IG in AAA20008 (PubMed:7841202).Curated2
Sequence conflicti97 – 98YE → IG in AAB33291 (PubMed:7841202).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055558129 – 144GRIIE…RGCSG → VMSDTQAWCCFQLKILP in isoform 2. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U11861 mRNA Translation: AAA20008.1
S77329 mRNA Translation: AAB33291.1
AK297784 mRNA Translation: BAH12665.1
AK316477 mRNA Translation: BAH14848.1
CR456951 mRNA Translation: CAG33232.1
AC004922 Genomic DNA No translation available.
CH236956 Genomic DNA Translation: EAL23881.1
CH471091 Genomic DNA Translation: EAW76670.1
CH471091 Genomic DNA Translation: EAW76671.1
CH471091 Genomic DNA Translation: EAW76672.1
CH471091 Genomic DNA Translation: EAW76673.1
BC022821 mRNA Translation: AAH22821.1
BC104670 mRNA Translation: AAI04671.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS5663.1 [P41223-1]

Protein sequence database of the Protein Information Resource

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PIRi
S52131

NCBI Reference Sequences

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RefSeqi
NP_003901.2, NM_003910.3 [P41223-1]
XP_005250727.1, XM_005250670.4 [P41223-2]
XP_005250728.1, XM_005250671.4 [P41223-2]
XP_005250731.1, XM_005250674.3 [P41223-1]
XP_016868249.1, XM_017012760.1 [P41223-2]
XP_016868250.1, XM_017012761.1 [P41223-2]
XP_016868251.1, XM_017012762.1 [P41223-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.380233

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000222969; ENSP00000222969; ENSG00000106245 [P41223-1]
ENST00000403633; ENSP00000386023; ENSG00000106245 [P41223-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
8896

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:8896

UCSC genome browser

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UCSCi
uc003uqf.4 human [P41223-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11861 mRNA Translation: AAA20008.1
S77329 mRNA Translation: AAB33291.1
AK297784 mRNA Translation: BAH12665.1
AK316477 mRNA Translation: BAH14848.1
CR456951 mRNA Translation: CAG33232.1
AC004922 Genomic DNA No translation available.
CH236956 Genomic DNA Translation: EAL23881.1
CH471091 Genomic DNA Translation: EAW76670.1
CH471091 Genomic DNA Translation: EAW76671.1
CH471091 Genomic DNA Translation: EAW76672.1
CH471091 Genomic DNA Translation: EAW76673.1
BC022821 mRNA Translation: AAH22821.1
BC104670 mRNA Translation: AAI04671.1
CCDSiCCDS5663.1 [P41223-1]
PIRiS52131
RefSeqiNP_003901.2, NM_003910.3 [P41223-1]
XP_005250727.1, XM_005250670.4 [P41223-2]
XP_005250728.1, XM_005250671.4 [P41223-2]
XP_005250731.1, XM_005250674.3 [P41223-1]
XP_016868249.1, XM_017012760.1 [P41223-2]
XP_016868250.1, XM_017012761.1 [P41223-2]
XP_016868251.1, XM_017012762.1 [P41223-1]
UniGeneiHs.380233

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4OEDX-ray2.79B56-70[»]
4OH6X-ray3.56B56-70[»]
4OKBX-ray2.95B56-70[»]
5MQFelectron microscopy5.90Q1-144[»]
5XJCelectron microscopy3.60N1-144[»]
5YZGelectron microscopy4.10N1-144[»]
5Z56electron microscopy5.10N1-144[»]
5Z57electron microscopy6.50N1-144[»]
6FF4electron microscopy16.00Q1-144[»]
ProteinModelPortaliP41223
SMRiP41223
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114413, 48 interactors
CORUMiP41223
IntActiP41223, 26 interactors
MINTiP41223
STRINGi9606.ENSP00000222969

PTM databases

iPTMnetiP41223
PhosphoSitePlusiP41223

Polymorphism and mutation databases

BioMutaiBUD31

Proteomic databases

EPDiP41223
jPOSTiP41223
MaxQBiP41223
PaxDbiP41223
PeptideAtlasiP41223
PRIDEiP41223
ProteomicsDBi55432

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
8896
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000222969; ENSP00000222969; ENSG00000106245 [P41223-1]
ENST00000403633; ENSP00000386023; ENSG00000106245 [P41223-1]
GeneIDi8896
KEGGihsa:8896
UCSCiuc003uqf.4 human [P41223-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
8896
DisGeNETi8896
EuPathDBiHostDB:ENSG00000106245.9

GeneCards: human genes, protein and diseases

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GeneCardsi
BUD31
HGNCiHGNC:29629 BUD31
HPAiHPA028943
MIMi603477 gene
neXtProtiNX_P41223
OpenTargetsiENSG00000106245
PharmGKBiPA144596513

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3404 Eukaryota
COG5132 LUCA
GeneTreeiENSGT00390000014300
HOGENOMiHOG000235066
HOVERGENiHBG080938
InParanoidiP41223
KOiK12873
OMAiCRGCSSD
OrthoDBi1236198at2759
PhylomeDBiP41223
TreeFamiTF105609

Enzyme and pathway databases

ReactomeiR-HSA-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
BUD31 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
8896

Protein Ontology

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PROi
PR:P41223

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000106245 Expressed in 235 organ(s), highest expression level in testis
ExpressionAtlasiP41223 baseline and differential
GenevisibleiP41223 HS

Family and domain databases

InterProiView protein in InterPro
IPR018230 BUD31/G10-rel_CS
IPR001748 G10
PANTHERiPTHR19411 PTHR19411, 1 hit
PfamiView protein in Pfam
PF01125 G10, 1 hit
PRINTSiPR00322 G10
PROSITEiView protein in PROSITE
PS00997 G10_1, 1 hit
PS00998 G10_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBUD31_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P41223
Secondary accession number(s): A4D274
, B7Z4S9, D6W5S6, Q6IB53, Q9UDV1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: October 10, 2002
Last modified: February 13, 2019
This is version 157 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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